Studies on the Constituents of the Seeds of Hernandia ovigera L. VI. Isolation and Structural Determination of Three Lignans(Pharmacognosy,Chemical)

Three kinds of lignans, including a new lignan, named hernolactone, were isolated from the seeds of Hernandia ovigera L. besides six previously reported lignans, desoxypodophyllotoxin (DPT), desoxypicropodophyllin, bursehernin, podorhizol, hernandin and dehydro-DPT. The structure of hernolactone was determined as (2R,3R)-3-(4'-hydroxy-3',5'-dimethoxybenzyl)-2-(3",4",5"-trimethoxybenzyl)-γ-butyrolactone (IV) and the other two lignans were identified as (-)-yatein ((-)-deoxypodorhizon) (V) and dehydropodophyllotoxin (IX).