Search Results:　 1-2 of 2

1

P-33 SYNTHETIC STUDIES OF (+)-LACTACYSTIN BASED ON THE ASYMMETRIC SYNTHESIS OF α-SUBSTITUTED SERINE DERIVATIVES [in Japanese]

SANO Shigeki , ISHII Takahiro , NAGAO Yoshimitsu , SHIRO Motoo

… Bislactim ether (11), obtained from prochiral σ-symmetric diethyl aminomalonate (1), was treated with base or Lewis acid in the presence of amine to form the enolate or enaminate (3). … Diastereoselective aldol-type reaction of the resultant enolate or enaminate (3) with chiral aldehyde (12) proceeded in a highly stereoselective manner to give the corresponding products (13), respectively. …

天然有機化合物討論会講演要旨集 (37), 463-468, 1995-09-01

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2

Synthesis of Acyclic 1,3-Polyols and Its Application to Structural Study of Natural Products [in Japanese]

MORI Yuji

… A 1,3-polyhydroxylated chain is often found on the backbone of biologically important natural products. … We have developed a new general synthetic method of 1,3-polyols based on the coupling of a chiral dithiane, a four-carbon unit, and an epoxide, followed by 1,3-diastereoselective reduction. …

Journal of the Pharmaceutical Society of Japan 113(6), 438-453, 1993-06-25

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