Search Results:　 1-20 of 1382

DOHI Tomotaka , MIYAUCHI Katsumi , IESAKI Takafumi , TSURUTA Ryo , TSUBOI Shuta , OGITA Manabu , KUBOTA Naozumi , KASAI Takatoshi , YOKOYAMA Takayuki , DAIDA Hiroyuki

… Bradykinin-induced endothelium-dependent relaxation at an adjacent segment distal to the SES evaluated using organ chambers was reduced compared with intact segments in control coronaries at 28 days. …

Circulation Journal 75(5), 1098-1106, 2011-04-25

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池澤 善郎

Clinical immunology & allergology 55(3), 312-321, 2011-03

Muramoto Kazuyo , Quan Rong-Dan , Namba Toshiharu [他]

Journal of natural medicines 65(2), 254-261, 2011

Maruyama Tomoharu , Ayabe Shinya , Murata Takahisa , Hori Masatoshi , Ozaki Hiroshi

… Pretreatment with BW245C (10 μM, 30 min) attenuated bradykinin (100 nM)-induced liver MF contraction. … Elevation of [Ca2+]i induced by bradykinin (100 nM) was partially suppressed by BW245C pretreatment (10 μM, 3 min). … 30 μM, 30 min) significantly reduced bradykinin-induced contraction. … These results suggest that prostanoid DP receptor agonism inhibits bradykinin-induced [Ca2+]i elevation and contraction through cAMP–PKA signal activation in rat liver MFs. …

Journal of Pharmacological Sciences 116(2), 197-203, 2011

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Takeshita Nobuaki , Yoshimi Eiji , Hatori Chie , Kumakura Fumiyo , Seki Nobuo , Shimizu Yasuaki

… In addition, the compound also inhibited bradykinin induced pain responses in normal rats. … or bradykinin-induced prostaglandin E2 production in a synovial cell line. …

Journal of Pharmacological Sciences 115(4), 481-489, 2011

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NAKAMURA Yasunori , OHKI Kohji

乳酸菌Lactobacillus helveticusは，発酵中に乳蛋白質を分解し，潜在するペプチドvalyl-prolyl-proline，isoleucyl-prolyl-prolineを産生する．両ペプチドは，アンジオテンシン変換酵素阻害活性を有する．この酵素は，アンジオテンシンIに作用し，強力な血圧上昇物質アンジオテンシンIIを産生することで知られる．動物実験および in vitro試験の …

Journal of Intestinal Microbiology 24(4), 259-264, 2010-10-01

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MANOLIS Athanasios J , MARKETOU Maria E , GAVRAS Irene , GAVRAS Haralambos

Hypertension research : clinical and experimental : official journal of the Japanese Society of Hypertension 33(8), 772-777, 2010-08-01

References (81)

IWANAGA Koichi , MURATA Takahisa , HORI Masatoshi , OZAKI Hiroshi

… 10 nM bradykinin) dose-dependently induced an increase in intracellular Ca2+ concentration in bovine ISMFs (passage 3 and 7). …

Journal of Pharmacological Sciences 112(1), 98-104, 2010-01-20

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ASHIDA H , Ozawa Hayato , Fujita Kiyotaka , Suzuki Shun'ichi , Yamamoto Kenji

… The enzyme directly transferred Galbeta1-3GalNAc to serine or threonine residues of bioactive peptides such as PAMP-12, bradykinin, peptide-T and MUC1a when Galbeta1-3GalNAcalpha1-pNP was used as a donor substrate. …

Glycoconj. J. 27(1), 125-132, 2010-01

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Asai Suzuka , Kimbara Noriaki , Tada Toyohiro , Imai Masaki , Campbell William , Okada Hidechika , Okada Noriko

… CPR removes the C-terminal arginine from inflammatory peptides such as C3a and C5a, bradykinin, enkephalin, and the thrombin-cleaved N-terminal fragment osteopontin (cleaved N-OPN). …

Biological & Pharmaceutical Bulletin 33(7), 1256-1259, 2010

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