WANG F.
,
Okamoto Yasuo
,
Inoki Isao
,
Yoshioka Kazuaki
,
Du Wa
,
Qi Xun
,
Takuwa Noriko
,
Gonda Koichi
,
Yamamoto Yasuhiko
,
Ohkawa Ryunosuke
,
Nishiuchi Takumi
,
Sugimoto Naotoshi
,
Yatomi Yutaka
,
Mitsumori Kunitoshi
,
Asano Masahide
,
Kinoshita Makoto
,
Takuwa Yoh
… Sphingosine-1-phosphate (S1P) is a biologically active sphingolipid that has pleiotropic effects in a variety of cell types including ECs, SMCs, and macrophages, all of which are central to the development of atherosclerosis. … S1PR2 was expressed in macrophages, ECs, and SMCs in atherosclerotic aortas. … ECs also showed reduced ROCK and NF-κB activities, with decreased MCP-1 expression and elevated eNOS phosphorylation. …
J. Clin. Invest. 120(11), 3979-3995, 2010-11-01
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