Search Results:　 1-20 of 2207

Ohmori Rei , Tsuruyama Tatsuaki

… Integration into the host genome is an essential step in the HIV-1 life cycle. … However, the host genome sequence that is favored by HIV-1 during integration has never been documented. … Here, we report that CD27, a T cell activation gene, includes a sequence that is a target for in vitro HIV-1 cDNA integration. …

PloS one 7(11), 2012-11-28

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Tran Vuong Thi , Ishizaki Azumi , Nguyen Cuong Hung , Hoan Huyen Thi , Pham Hung Viet , Bi Xiuqiong , Pham Thuc Van , Ichimura Hiroshi

… We reported previously that the prevalence of drug-resistant HIV-1 among antiretroviral therapy (ART)-naive individuals in Northern Vietnam was 2.9% in 2007 and 6.2% in 2008. … To investigate the continuing trend of prevalence, we collected plasma samples from 958 individuals in Hai Phong and Hanoi in 2009, extracted viral RNA from HIV-1 antibody-positive samples, and analyzed them genetically. …

AIDS Research and Human Retroviruses 28(10), 1349-1351, 2012-10-01

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隅田 泰生 , 西 順一郎 , 岡本 実佳 他

Bio industry 29(10), 31-36, 2012-10-00

Furukawa Ayako , Okamura Hideyasu , Morishita Ryo , Matsunaga Satoko , Kobayashi Naohiro , Ikegami Takahisa , Kodaki Tsutomu , Takaori-Kondo Akifumi , Ryo Akihide , Nagata Takashi , Katahira Masato

… Five different combinatorially (15)N-labeled samples were prepared and backbone resonance assignments were made by applying Otting's method, with which the amino acid types of the [(1)H, (15)N] HSQC resonances were automatically identified using the five samples (Wu et al., 2006) [14]. … For many residues, two distinct resonances were observed, which is thought to be due to the structural heterogeneity between the two protomers in the APV:XMRV PR=1:2 complex. …

Biochemical and biophysical research communications 425(2), 284-289, 2012-08-24

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？折 晃史

血液内科 65(2), 283-288, 2012-08-00

Ichushi Web

Shankar Esaki Muthu , Velu Vijayakumar , Vignesh Ramachandran 他

Microbiology and immunology 56(8), 497-505, 2012-08-00

Mori Masahiko , Matsuki Kei , Maekawa Tomoyuki , Tanaka Mari , Sriwanthana Busarawan , Yokoyama Masaru , Ariyoshi Koya

… Objectives are 1) to evaluate the novel in silico model in predicting previously reported epitopes in comparison with existing program, and 2) to apply the model to predict optimal epitopes with HLA using experimental results. … It was applied to predict 52 HIV best-defined CTL epitopes from 15-mer overlapping peptides, and its predictive ability was compared with the HLA binding motif-based program of HLArestrictor. …

PLoS ONE 7(7), e41703, 2012-07-27

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SUGIURA Aya , IWAHARA Kunihiro , SUGA Yasuyuki , UCHIYAMA Sachinori , MAEKAWA Masato

臨床病理 60(4), 300-305, 2012-04-25

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新谷 英滋 , 高橋 秀実

臨床免疫・アレルギー科 57(3), 269-274, 2012-03-00

Ichushi Web

Iwami Shingo , Holder Benjamin P , Beauchemin Catherine A A , Morita Satoru , Tada Tetsuko , Sato Kei , Igarashi Tatsuhiko , Miura Tomoyuki

… Our analysis allowed us to extract an infected cell half-life of 14.1 h, a half-life of SHIV-KS661 infectiousness of 17.9 h, a virus burst size of 22.1 thousand RNA copies or 0.19 TCID50, and a basic reproductive number of 62.8. … Furthermore, we calculated that SHIV-KS661 virus-infected cells produce at least 1 infectious virion for every 350 virions produced. …

Retrovirology 9, 2012-02-25

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