検索結果:　 23件中 1-20 を表示

高橋 誠 , 緒方 憲太郎 , 二神 幸次郎 , 堤 一貴 , 松本 浩一 , 鶴田 美恵子

… The administration of Hange-shashin-to is effective in preventing diarrhea caused by irinotecan hydrochloride (CPT-11) when they are coadministered but a high incidence of constipation has been reported when CPT-11 is used in combination with anti-diarrhea drugs. …

医療薬学 35(3), 219-222, 2009-03-10

CiNii PDF - 定額アクセス可能  医中誌 参考文献11件

KAWASHIMA Keiko , NOMURA Asano , MAKINO Toshiaki , SAITO Ken-ichi , KANO Yoshihiro

… Hange-shashin-to (HST) has been used as an herbal formula to treat inflammatory ulcerative gut diseases complicated with psychoneurosis in Japanese traditional Kampo medicine. …

Biological & pharmaceutical bulletin 27(10), 1599-1603, 2004-10-01

CiNii PDF - オープンアクセス  J-STAGE 医中誌 CrossRef 参考文献16件 被引用文献8件

関谷 倫子 , 森元 康夫

人参湯,半夏瀉心湯,六君子湯および小半夏加茯苓湯について,ラット術後イレウスモデルに対する作用を調べた。ラットをエーテル麻酔下に開腹した後,小腸および盲腸を腹腔外に5分間露呈させることで術後イレウスモデルを作製した。このイレウスモデルでは,活性炭末マーカーの輸送率を計測することで評価した腸管運動が,麻酔処置のみの動物に比べて著しく低下した。消化管運動促進薬のシサプリド,モサプリド,メトクロプラミド …

日本東洋醫學雜誌 54(4), 785-790, 2003-07-20

CiNii PDF - オープンアクセス  Journal@rchive 医中誌 CrossRef 参考文献15件

NAITO Takafumi , ITOH Hiroki , YASUNAGA Fumitaka , TAKEYAMA Masaharu

… Hange-shashin-to has been used for chronic hypofunction of the gastrointestinal tract and to improve functional abnormalities of the upper and lower gastrointestinal system. …

Biological & pharmaceutical bulletin 25(3), 327-331, 2002-03-01

CiNii PDF - オープンアクセス  J-STAGE 医中誌 CrossRef 参考文献35件 被引用文献13件

瓜田 純久 , 三木 一正

… Helicobacter pylori (H.pylori) is known to be the most important cause of chronic gastritis and have a role in the pathogenesis of gastroduodenal ulcers. … pylori is sensitive to many kinds of antibiotics in vitro. … pylori infection has proven difficult to cure. … In order to reduce side effects and improve the eradication rate of H. … it is necessary to modify the dual therapy. …

和漢医薬学雑誌 17(1), 12-16, 2000-02-25

CiNii PDF - オープンアクセス  医中誌

KASE Yoshiko , SAITOH Kazuko , ISHIGE Atsushi , KOMATSU Yasuhiro

… To determine the mechanisms by which Hange-shashin-to (TJ-14) reduces prostaglandin E2 (PGE2) levels, the effects on blood corticosterone levels were examined in vivo and the effects on cyclooxygenase (COX) activity in virto assessed. … TJ-14,orally administered to rats at dose levels between 125 and 1000 mg/kg, caused a dose-dependent increase in blood corticosterone levels. …

Biological & pharmaceutical bulletin 21(12), 1277-1281, 1998-12-15

CiNii PDF - オープンアクセス  Journal@rchive 医中誌 CrossRef 参考文献36件 被引用文献3件

KASE Yoshio , SAITOH Kazuko , YUZURIHARA Mitsutoshi , ISHIGE Atsushi , KOMATSU Yasuhiro

… The effects of Hange-shashin-to (TJ-14) on cholera toxin-induced intestinal fluid secretion were studied to elucidate the mechanism by which this kampo medicine manifests antidiarrheal effects. …

Biological & pharmaceutical bulletin 21(2), 117-120, 1998-02-15

CiNii PDF - オープンアクセス  Journal@rchive 医中誌 CrossRef 参考文献30件 被引用文献3件

KASE Yoshio , HAYAKAWA Terumasa , ISHIGE Atsushi , ABURADA Masaki , KOMATSU Yasuhiro

… The effects of Hange-shashin-to (TJ-14) were examined regarding the amount of prostaglandin E_2 (PGE_2) and the water absorbind capacity in the large intestine of rats. … Repeated oral administration of TJ-14 at doses of 125 to 1000 mg/kg revealed a significant decrease in PGE_2 content in the colonic mucosa and also the promotion of colonic water absorption in a dose dependent manner. …

Biological & pharmaceutical bulletin 20(9), 954-957, 1997-09-15

CiNii PDF - オープンアクセス  Journal@rchive 医中誌 CrossRef 参考文献29件 被引用文献5件

KASE Yoshio , HAYAKAWA Terumasa , TAKEDA Sigefumi , ISHIGE Atsusi , ABURADA Masaki , OKADA Minoru

… We attempted to characterize the antidiarrheal action of Hange-shashin-to (TJ-14), a kampo medicine, by comparing its action with that of loperamide. … The oral administration of TJ-14 caused the dose-dependent suppression of castor oil-induced diarrhea at 250 to 1000 mg/kg. …

Biological & pharmaceutical bulletin 19(10), 1367-1370, 1996-10-15

CiNii PDF - オープンアクセス  Journal@rchive 医中誌 CrossRef 参考文献24件 被引用文献11件