Search Results:　 1-20 of 32

1

Difference in fine specificity to polysaccharides of Candida albicans mannoprotein between mouse SIGNR1 and human DC-SIGN.

Takahara Kazuhiko , Arita Takuya , Tokieda Sumika , Shibata Nobuyuki , Okawa Yoshio , Tateno Hiroaki , Hirabayashi Jun , Inaba Kayo

… C-type lectin SIGNR1 directly recognizes Candida albicans and zymosan and has been considered to share properties of polysaccharide recognition with human DC-SIGN (hDC-SIGN). … Consistent with these results, RAW264.7 cells expressing hDC-SIGN in which the carbohydrate recognition domain (CRD) was replaced with that of SIGNR1 (RAW-chimera) produced comparable amounts of interleukin 10 (IL-10) in response to glycans from C. …

Infection and immunity 80(5), 1699-1706, 2012-05-00

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2

P-034 Micronucleus test and comet assay using human hepatocyte chimera mice(PXB Mouse(R))(Poster Presentation) [in Japanese]

Fukumuro Masahito , Tanaka Jin , Masumori Shoji , Nakajima Madoka , Hayashi Makoto , Ishida Yuji , Kakuni Masakazu , Tateno(Mukaidani) Chise

Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan (40), 109, 2011-10-20

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3

An Integrin alpha 4 beta 7.IgG Heterodimeric Chimera Binds to MAdCAM-1 on High Endothelial Venules in Gut-Associated Lymphoid Tissue

Hoshino Hitomi , Kobayashi Motohiro , Mitoma Junya , Sato Yoshiko , Fukuda Minoru , Nakayama Jun

… To probe functional MAdCAM-1 in tissue sections, we developed a soluble integrin alpha 4 beta 7 heterodimeric IgG chimera by joining the extracellular region of mouse integrin alpha 4 and beta 7 subunits to a human IgG Fc domain. …

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 59(6), 572-583, 2011-06-00

IR CrossRef
4

Engineering of a novel chimera of superoxide dismutase and Vitreoscilla hemoglobin for rapid detoxification of reactive oxygen species(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)

Isarankura-Na-Ayudhya Chartchalerm , Yainoy Sakda , Tantimongcolwat Tanawut , Bulow Leif , Prachayasittikul Virapong

… The genes encoding human manganese superoxide dismutase (MnSOD) and Vitreoscilla hemoglobin (VHb) were fused in-frame to generate a bifunctional enzyme that possessed MnSOD and peroxidase-like activities. …

Journal of bioscience and bioengineering 110(6), 633-637, 2010-12-00

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5

A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid supresses the growth of malignant methothelioma cells in vitro

Kawata Eri , Ashihara Eishi , Nakagawa Yoko , Kiuchi Takahiro , Ogura Mai , Yao Hisayuku , Sakai Kazuki , Tanaka Ruriko , Nagao Rina , Yokota Asumi , Takeuchi Miki , Kimura Shinya , Hirai Hideyo , Maekawa Taira

… We generated a DNA-chimeric siRNA against polo-like kinase-1 (PLK-1), which was more stable in human serum than the non-chimeric siRNA. …

Cancer Lett 294(2), 245-253, 2010-08-28

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6

Tarantula Toxin ProTx-I Differentiates Between Human T-type Voltage-Gated Ca2+ Channels Cav3.1 and Cav3.2

Ohkubo Tsuyako , Yamazaki Jun , Kitamura Kenji

… currents through recombinant human T-type voltage-gated Ca2+ … The ProTx-I sensitivity was markedly reduced in the hCav3.1/S3S4 chimera as compared to the original hCav3.1 channel, while the hCav3.2/S3S4 chimera exhibited greater ProTx-I sensitivity than the original hCav3.2 channel. …

Journal of Pharmacological Sciences 112(4), 452-458, 2010

J-STAGE CrossRef
7

Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera

SASAKI Ko , YAMAGATA Tetsuya , MITANI Kinuko

Cancer Sci 99(2), 414-422, 2008-02-10

Ichushi Web References (51) Cited by (1)
8

Putative Embryonic Stem Cell Lines from Pig Embryos

VACKOVA Irena , UNGROVA Andrea , LOPES Federica

… Logically, before application of stem cell therapies into a human medicine, it is necessary to verify the efficiency and safety of these methods with an acceptable animal model. …

Journal of Reproduction and Development 53(6), 1137-1149, 2007-12-01

J-STAGE Ichushi Web CrossRef References (84) Cited by (2)
9

Proteinase inhibitory activity of recombinant rabbit α-1-antiproteinases expressed in Escherichia coli

Saito Akio

… However, the fusion proteins of the F isoform of rabbit a-1-antiproteinase and human α-1-antitrypsin inhibited those proteinases. … The plasmids having a chimera sequence of the S-22 and F forms were expressed and the fusion proteins were examined for proteinase inhibitory activity. …

Acta medica Kinki University 32(2), 57-65, 2007-12-00

CiNii Fulltext PDF - Open Access Ichushi Web
10

Lateralization for the Production of Facial Expressions in Infant Chimpanzees and Humans(Infant & Nursery Education, Developmental Psychology) [in Japanese]

Nakamura(Inoue) Noriko

… Human and non-human primates have in common, facial emotional expressions as one of the means of communication. … Facial emotion plays a very important part for primates and human infants who have not yet acquired spoken language. … We constructed composite chimera faces of the right or left side of their frontal facial emotions, such as smiling and crying faces. …

學苑 800, 75-80, 2007-06-01

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11

Establishment of a Human Hepatoma Cell Line HepG2-A10 for a Reporter Gene Assay of Arylhydrocarbon Receptor Activators

Sekimoto Masashi , Kawamagari Hiroto , Nakatani Saki , Nemoto Kiyomitsu , Degawa Masakuni

… To establish a human hepatic cell line for a convenient reporter gene assay of arylhydrocarbon receptor (AhR) activators, the chimera plasmid containing xenobiotic responsible element (XRE), minimal SV40 promoter, and luciferase reporter gene and the expression vector pRC/CMV containing a neomycin-resistant gene were co-transfected into a human hepatoma cell line, HepG2. …

Genes and environment : the official journal of the Japanese Environmental Mutagen Society 29(1), 11-16, 2007-02-20

CiNii Fulltext PDF - Open Access Ichushi Web References (25) Cited by (1)
12

SBD. 4 stimulates regenerative processing in vitro, and wound healing in genetically diabetic mice and in human skin/severe-combined immunodeficiency mouse chimera

ZHAO Hui , MORTEZAEI Reza , WANG Yanrong , SHENG Xinsheng , ARIA Fariba , BOJANOWSKI Krzysztof

Wound repair and regeneration 14(5), 593-601, 2006-09-01

References (27)
13

Characterization of two mutations of the protein S gene observed in Japanese thrombophilic patients [in Japanese]

INOUE Sumiko , FUJII Tomomi , URATA Michiyo , WADA Yui , ONO Miyuki , KURIHARA Masako , CHUMPIA Worawan , IIDA Hiroko , KINOSHITA Sachiko , TSUDA Hiroko , KANG Dongchon , HAMASAKI Naotaka

… プロテインS活性低下を示した血栓症患者に見出された変異型分子2種類（Thr37MetおよびCys206Phe）をhuman embryo kidney 293（HEK293）細胞に安定発現させ，細胞培養上清中のプロテインS活性と蛋白質量を測定した．さらに，これら変異型分子とGreen fluorescence protein（GFP）とのキメラ体を用いて細胞内移行の検討を行った．Thr37Met変異型の培養上清中のプロテインS活性は低下していたが分泌される蛋白質量に異常はなく，Thr37Met変異 …

Japanese Journal of Thrombosis and Hemostasis 16(6), 641-649, 2005-12-01

J-STAGE Ichushi Web CrossRef References (26) Cited by (3)
14

Hypoglycemic Effects of Turmeric (Curcuma longa L. Rhizomes) on Genetically Diabetic KK-A^y Mice(Communications to the Editor)

KURODA Minpei , MIMAKI Yoshihiro , NISHIYAMA Tozo , MAE Tatsumasa , KISHIDA Hideyuki , TSUKAGAWA Misuzu , TAKAHASHI Kazuma , KAWADA Teruo , NAKAGAWA Kaku , KITAHARA Mikio

… In an in vitro evaluation, the extract stimulated human adipocyte differentiation in a dose-dependent manner and showed human peroxisome proliferator-activated receptor (PPAR)-γ ligand-binding activity in a GAL4-PPAR-γ chimera assay. …

Biological & pharmaceutical bulletin 28(5), 937-939, 2005-05-01

CiNii Fulltext PDF - Open Access J-STAGE Ichushi Web CrossRef References (10) Cited by (2)
15

Therapeutic Angiogenesis Using Novel VEGF-E/human PIGF Chimera Genes(Angiogenesis 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

Inoue Natsuo , Kondo Takahisa , Kobayashi Koichi , Numaguchi Yasushi , Murohara Toyoaki , Shibuya Masabumi

Circulation journal : official journal of the Japanese Circulation Society 69(Supplemnt_I), 150-151, 2005-03-01

CiNii Fulltext PDF - Open Access Ichushi Web
16

Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera

MEULEMAN P.

Hepatology 41, 847-856, 2005

CrossRef Cited by (3)
17

Effective Production of Microinjectable Blastocysts for Germ-Line Transmission of Embryonic Stem Cells

KIM Sun-Uk , HAN Ying-Hao , LEE Tae-Hoon , HYUN Byung-Hwa , LEE Sang-Ho , LEE Dong-Seok , YU Dae-Yeul

Blastocysts of C57BL/6 mice obtained either 2.5 or 3.5 days post-coitum (dpc) were examined for efficient microinjection after overnight in vitro culture. Incidences of zona-free em …

Experimental Animals 53(5), 475-477, 2004-10-00

J-STAGE Ichushi Web CrossRef References (13)
18

Expression and Visualization of a Human Interferon-β-Enhanced Green Fluorescent Protein Chimeric Molecule in Cultured Cells (Biochemistry/Molecular Biology)

NAKAMURA Masaru , MARUYAMA Masato , YAMASHITA Fumiyoshi , TAKAKURA Yoshinobu , HASHIDA Mitsuru , WATANABE Yoshihiko

… We have constructed a recombinant cDNA encoding the chimeric protein between human IFN-β (HuIFN-β) and enhanced green fluorescent protein (EGFP) to elucidate the intracellular localization of IFN-β. … These results indicate that the HuIFN-β-EGFP chimeric gene was expressed as a chimeric protein and the chimera was transported via the regular secretory pathway in the cells. …

Biological & pharmaceutical bulletin 27(3), 411-414, 2004-03-01

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19

Processing of O-linked Glycosylation in the Chimera Consisting of α-Subunit and Carboxyl-terminal Peptide of the Human Chorionic Gonadotropin β-Subunit is Affected by Dimer Formation with Follicle-stimulating Hormone β-Subunit

FURUHASHI MADOKA , SUGANUMA NOBUHIKO

Endocrine journal 51(1), 53-59, 2004-02-01

Ichushi Web References (38)
20

The chimeric CYP21P/CYP21 gene and 21-hydroxylase deficiency

LEE Hsien-Hsiung

Journal of Human Genetics 49(2), 65-72, 2004-02-01

Ichushi Web References (46)

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