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The Study to Reduce the Hemolysis Side Effect of Puerarin by a Submicron Emulsion Delivery System(Pharmacology)
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YUE Peng-Fei
,
YUAN Hai-Long
,
ZHU Wei-Feng
,
CONG Long-Bo
,
XIE Huan
,
LIU Zhi-Guo
,
WANG Lu-Jun
,
XIAO Xiao-He
… The mechanism to reduce the hemolysis side effect of puerarin was studied by blood cell counts in rabbits. … Such observations indicated that the intravascular hemolysis occurred at 42, 43 d in puerarin i.v group rabbits, the hemolysis did not occur for puerarin emulsion group rabbits. … It could be concluded that puerarin submicron emulsions prepared markedly reduced the hemolysis effect of puerarin. …
Biological & pharmaceutical bulletin 31(1), 45-50, 2008-01-01
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