Search Results:　 1-20 of 53562

  • 1

    Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer.

    Kurosaki Tomoaki , Higuchi Norihide , Kawakami Shigeru , Higuchi Yuriko , Nakamura Tadahiro , Kitahara Takashi , Hashida Mitsuru , Sasaki Hitoshi

    … The addition of a non-specific aptamer to the pDNA/PEI complex decreased gene expression in the human lung cancer cell line, A549 cells expressing MUC1 regularly. …

    Gene 491(2), 205-209, 2012-01-10

    IR CrossRef

  • 2

    A Case of Small Bowel Metastases from Lung Cancer with Intestial Obstruction  [in Japanese]

    Arai Junichi.et.al.

    (症例)75歳男性(病歴)腹痛、嘔吐を主訴に当院受診。腹部CTにて小腸に径5cm大の腫瘤を認めた。また胸部レントゲン・胸部CTにて右S6に肺癌が疑われた。画像上腸閉塞所見を認め、まず小腸部分切除術を行った。小腸の病理組織診断では低分化腺癌であったが、転移性か原発かは確定できなかった。肺腫瘍は、気管支鏡の擦過細胞診でclassV、低分化腺癌と診断され、その後の胸腹部CTにて腎転移、背部皮膚、大腿の皮 …

    Nagasaki Igakkai zasshi = Nagasaki medical journal 86(3), 140-145, 2011-12-25

  • 3

    Two cases of primary lung cancer complicate by functioning adrenal tuuor  [in Japanese]

    Morino Shigeyuki.et.al.

    術前に副腎腫瘍を指摘された肺癌の2例を経験した。症例1は58歳女性。胸部CTで左肺S6に24mmの結節と右副腎に30mmの腫瘤を認めた。肺腫瘍は気管支鏡生検で非小細胞肺癌と診断した。副腎腫瘍はPET-CTで副腎転移が疑われ、血中カテコーラミン値から褐色細胞腫の可能性も考えた。右副腎切除を先行し、病理学的に褐色細胞腫と診断した。二期的に左下葉切除術を行い、低分化腺癌、病期はpT1bN0M0 stag …

    Nagasaki Igakkai zasshi = Nagasaki medical journal 86(3), 140-145, 2011-12-25

  • 4

    Phase II Trial of Biweekly Paclitaxel and Gemcitabine as Second-Line Chemotherapy for Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy

    KOBAYASHI Takashi , KOIZUMI Tomonobu , YASUO Masanori , TSUSHIMA Kenji , YAMAMOTO Hiroshi , KUBO Keishi

    … A phase II study was conducted to evaluate the feasibility and efficacy of biweekly administration of paclitaxel and gemcitabine in patients with non-small cell lung cancer (NSCLC) who had been treated previously with platinum-based chemotherapy. …

    信州医学雑誌 59(6), 411-418, 2011-12-10

    IR

  • 5

    Investigation of irradiation conditions for recurrent breast cancer in JRR-4

    Horiguchi H. , Nakamura T. , Kumada H. , Yanagie H. , Suzuki M. , Sagawa H. , 熊田 博明

    … In this study, the irradiation technique for a total mastectomy patient with recurrent cancer was optimized by dosimetric calculations using JAEA computational dosimetry system (JCDS). … The results revealed that equivalent doses of lung, heart, liver and skin were similar in each irradiation technique due to the isotropic scattering of thermal neutrons in the body. …

    Applied radiation and isotopes 69(12), 1882-1884, 2011-12

    IR CrossRef

  • 6

    Clinical Outcome of Amrubicin Therapy According to the Prior Chemotherapy Sensitivities of Extensive Small Cell Lung Cancer

    Mitsuoka Shigeki , Kudoh Shinzoh , Kimura Tatsuo , Yoshimura Naruo , Tanaka Hidenori , Suzumura Tomohiro , Umekawa Kanako , Nagata Misato , Ueda Takako , Hirata Kazuto

    Osaka City Medical journal 57(2), 59-66, 2011-12

  • 7

    Toxicoproteomic evaluation of carbon nanomaterials in vitro

    Haniu Hisao , Matsuda Yoshikazu , Usui Yuki , Aoki Kaoru , Shimizu Masayuki , Ogihara Nobuhide , Hara Kazuo , Okamoto Masanori , Takanashi Seiji , Ishigaki Norio , Nakamura Koichi , Kato Hiroyuki , Saito Naoto

    … These properties are thought to cause malignant mesothelioma and lung cancer. …

    Journal of Proteomics 18(12), 2703-2712, 2011-11-18

    IR CrossRef

  • 8

    Phase I study of concurrent real-time tumor-tracking thoracic radiation therapy with paclitaxel and carboplatin in locally advanced non-small cell lung cancer

    Sakakibara-Konishi Jun , Oizumi Satoshi , Kinoshita Ichiro , Shinagawa Naofumi , Kikuchi Junko , Kato Mototsugu , Inoue Tetsuya , Katoh Norio , Onimaru Rikiya , Shirato Hiroki , Dosaka-Akita Hirotoshi , Nishimura Masaharu

    … Introduction: Although paclitaxel with carboplatin and thoracic radiotherapy has improved survival for patients with locally advanced unresectable non-small cell lung cancer (NSCLC), the optimal dose of paclitaxel has not been well defined in Japan. … Before treatment, gold markers were inserted into the lung and the mediastinum of all patients. …

    Lung Cancer 74(2), 248-252, 2011-11

    IR CrossRef

  • 9

    Maintenance chemotherapy for non-small-cell lung cancer.

    Kim Young Hak , Mishima Michiaki

    … Currently, platinum-based combination chemotherapy is the standard first-line chemotherapy for non-small-cell lung cancer (NSCLC). …

    Cancer treatment reviews 37(7), 505-510, 2011-11

    IR CrossRef

  • 10

    Efficacy of increased-dose erlotinib for central nervous system metastases in non-small cell lung cancer patients with epidermal growth factor receptor mutation.

    Togashi Yosuke , Masago Katsuhiro , Fukudo Masahide , Tsuchido Yasuhiro , Okuda Chiyuki , Kim Young Hak , Ikemi Yasuaki , Sakamori Yuichi , Mio Tadashi , Katsura Toshiya , Mishima Michiaki

    … Recent reports indicate that refractory central nervous system (CNS) metastases of non-small cell lung cancer (NSCLC) are improved by high-dose gefitinib or erlotinib administration. …

    Cancer chemotherapy and pharmacology 68(4), 1089-1092, 2011-10

    IR CrossRef

  • 11

    Phase II Study of Irinotecan plus S-1 Combination for Previously Untreated Advanced Non-Small Cell Lung Cancer: Hokkaido Lung Cancer Clinical Study Group Trial (HOT) 0601

    Akie Kenji , Oizumi Satoshi , Ogura Shigeaki , Shinagawa Naofumi , Kikuchi Eiki , Fukumoto Shinichi , Harada Masao , Kinoshita Ichiro , Kojima Tetsuya , Harada Toshiyuki , Fujita Yuka , Ohsaki Yoshinobu , Dosaka-Akita Hirotoshi , Isobe Hiroshi , Nishimura Masaharu

    … Objective: Platinum-free regimens can represent an alternative for advanced non-small cell lung cancer (NSCLC) if similar efficacy is provided with better tolerability. …

    Oncology 81(2), 84-90, 2011-10

    IR CrossRef

  • 12

    A phase II study of amrubicin and topotecan combination therapy in patients with relapsed or extensive-disease small-cell lung cancer: Okayama Lung Cancer Study Group Trial 0401

    Nogami Naoyuki , Hotta Katsuyuki , Kuyama Shoichi , Kiura Katsuyuki , Takigawa Nagio , Chikamori Kenichi , Shibayama Takuo , Kishino Daizo , Hosokawa Shinobu , Tamaoki Akihiko , Harita Shingo , Tabata Masahiro , Ueoka Hiroshi , Shinkai Tetsu , Tanimoto Mitsune

    … Backgrounds: Chemotherapy is a mainstay in the treatment of extensive-disease small-cell lung cancer (ED-SCLC), although the survival benefit remains modest. …

    Lung Cancer 74(1), 80-84, 2011-10

    IR CrossRef

  • 13

    Radiofrequency Ablation of Lung Cancer at Okayama University Hospital: A Review of 10 Years of Experience

    Hiraki Takao , Gobara Hideo , Mimura Hidefumi , Toyooka Shinichi , Fujiwara Hiroyasu , Yasui Kotaro , Sano Yoshifumi , Iguchi Toshihiro , Sakurai Jun , Tajiri Nobuhisa , Mukai Takashi , Matsui Yusuke , Kanazawa Susumu

    … The application of radiofrequency ablation for the treatment of lung cancer by our group at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences began in June 2001, and in the present report, we review our 10-year experience with this treatment modality at Okayama University Hospital. … The local efficacy of radiofrequency ablation for the treatment of lung cancer depends on tumor size and the type of electrode used, but not on tumor type. …

    Acta Medica Okayama 65(5), 287-297, 2011-10

    IR

  • 14

    Establishment of Regional Alliance Clinical Pathways for Gastrointestinal Cancer in Tokushima

    Morimoto Shinya , Shimada Mitsuo , 森本 慎也 , 島田 光夫 , モリモト シンヤ , シマダ ミツオ

    … Purpose : The maintenance of regional alliance clinical pathways for five cancers (lung, stomach, liver, large intestine, and breast) has been requested along with a readjustment of specific requirements for a plan to promote cancer control measures based on the Cancer Control Act. … The aim of this study was to clarify the usefulness of regional alliance clinical pathways for cancer of the gastrointestinal tract in Tokushima Prefecture. …

    福岡医学雑誌 102, 267-272, 2011-09-25

    IR

  • 15

    A Case of Amoebic Lung Abscess with Entamoeba gingivalis  [in Japanese]

    Hasumi Tohru , Saito Yasuki , Abe Jiro , Hoshi Fumihiko , Kawamura Masaki , Tanaka Ryota

    背景. 歯肉アメーバは口腔内に寄生するが病原性は有さないと考えられている.症例. 53歳,女性.喀血を主訴に来院.胸部CT上,右上葉に膿瘍性腫瘤を認めた.気管支鏡擦過にて口腔内常在菌のみ(抗酸菌・真菌陰性),細胞診class Iであった.肺膿瘍として抗菌薬投与を行うも陰影の改善は得られなかった.2回目の気管支鏡検査にて擦過物から放線菌を認めたためcotrimoxazoleが投与された.半年間の治療 …

    The journal of the Japan Society for Bronchology 33(5), 331-336, 2011-09-25

    CiNii Fulltext PDF - Open Access  Ichushi Web

  • 16

    A Case of Mucoepidermoid Carcinoma with Obstructive Pneumonia Removed by Bronchoscopy  [in Japanese]

    Watanabe Tatsuaki , Endo Chiaki , Sakurada Akira , Ishibashi Naoya , Eba Shunsuke , Notsuda Hirotsugu , Watanabe Yui , Suzuki Takaya , Oishi Hisashi , Maeda Sumiko , Noda Masafumi , Hoshikawa Yasushi , Okada Yoshinori , Kondo Takashi

    背景. 閉塞性肺炎を伴った粘表皮癌の1例を報告する.症例. 26歳女性,肺炎と右無気肺のため近医に入院した.抗生剤による治療後も右無気肺は改善しなかった.気管支鏡検査では右中間幹を閉塞する腫瘍性病変を認め,病理組織検査で粘表皮癌と診断された.治療のため当科に転院後,気管支鏡下に高周波ナイフなどを用いて腫瘍を摘除した.1週間後の気管支鏡検査ではフィブリン塊が右主気管支までせり出していたため摘除した. …

    The journal of the Japan Society for Bronchology 33(5), 321-325, 2011-09-25

    CiNii Fulltext PDF - Open Access  Ichushi Web

  • 17

    Engagement of Overexpressed Her2 with GEP100 Induces Autonomous Invasive Activities and Provides a Biomarker for Metastases of Lung Adenocarcinoma

    Menju Toshi , Hashimoto Shigeru , Hashimoto Ari , Otsuka Yutaro , Handa Haruka , Ogawa Eiji , Toda Yoshinobu , Wada Hiromi , Date Hiroshi , Sabe Hisataka

    … Overexpression of Her2/ErbB2/Neu in cancer is often correlated with recurrent distant metastasis, although the mechanism still remains largely elusive. … We have previously shown that EGFR, when tyrosine-phosphorylated, binds to GEP100/BRAG2 to activate Arf6, which induces cancer invasion and metastasis. … We now show that overexpressed Her2 in lung adenocarcinoma cells also employs GEP100. …

    PLoS One 6(9), e25301, 2011-09-22

    IR CrossRef

  • 18

    Changes in aromatase (CYP19) gene promoter usage in non-small cell lung cancer

    Demura Masashi , Demura Yoshiki , Ameshima Shingo , Ishizaki Takeshi , Sasaki Masato , Miyamori Isamu , Yamagishi Masakazu , Takeda Yoshiyu , Bulun Serdar E.

    … Inhibition of aromatase has been reported to downregulate lung tumor growth. … The genetic basis for CYP19 gene expression and aromatase activity in lung cancer remains poorly understood. … We analyzed tissues from 15 patients with non-small cell lung cancer (NSCLC) to evaluate CYP19 promoter usage and promoter-specific aromatase mRNA levels in NSCLC tumor tissues and adjacent non-malignant tissues. …

    Lung Cancer 73(3), 289-293, 2011-09

    IR CrossRef

  • 19

    Pleomorphic Carcinoma of the Lung Producing Granulocyte Colony-Stimulating Factor : Report of a Case

    WADA HIRONOBU , YOSHIDA SHIGETOSHI , ISHIBASHI FUMIHIRO , MIZOBUCHI TERUAKI , MORIYA YASUMITSU , HOSHINO HIDEHISA , OKAMOTO TATSURO , SUZUKI MAKOTO , SHIBUYA KIYOSHI , YOSHINO ICHIRO

    Surgery today : the Japanese journal of surgery 41(8), 1161-1165, 2011-08-01

    References (9)

  • 20

    How Many Pathological T1N0M0 Non-Small Cell Lung Cancers Can Be Completely Resected in One Segment? Special Reference to High-Resolution Computed Tomography Findings

    HORINOUCHI HIROHISA , NOMORI HIROAKI , NAKAYAMA TAKASHI , KOHNO MITSUTOMO , IZUMI YOTARO , WATANABE MASAZUMI , KAWAMURA MASAFUMI

    Surgery today : the Japanese journal of surgery 41(8), 1062-1066, 2011-08-01

    References (19)

Related Authors