Search Results:　 1-20 of 2476

1

The KEGG databases and tools facilitating omics analysis: latest developments involving human diseases and pharmaceuticals.

Kotera Masaaki , Hirakawa Mika , Tokimatsu Toshiaki , Goto Susumu , Kanehisa Minoru

… The desktop application KegArray and many Web-based tools are tightly integrated with the KEGG knowledgebase, which helps visualize and interpret large amount of data derived from high-throughput measurement techniques including microarray, metagenome, and metabolome analyses. …

Methods in molecular biology 802, 19-39, 2012

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2

Two-way AIC: A Novel Method for Detection of Differentially Expressed Genes from Microarray Data Sets [in Japanese]

Koki Tsuyuzaki , Daisuke Tominaga , Yeondae Kwon , Satoru Miyazaki

DNA マイクロアレイの遺伝子発現データから、真に生物学的に繋がりがある遺伝子群を選択的に検出するのは未だ難しい問題であり、今後も更なる発展が求められている。近年では大量の遺伝子発現データが個人レベルで取得可能となってきた。そこで本研究では、複数の比較実験データを統合したメタデータセットから得られる実験側で見た変動と遺伝子側で見た変動を利用し、両方向で発現変動を判定する、two-way AIC と …

IPSJ SIG technical reports 2011-BIO-27(4), 1-6, 2011-11-24

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3

Two-way AIC: A Novel Method for Detection of Differentially Expressed Genes from Microarray Data Sets [in Japanese]

Koki Tsuyuzaki , Daisuke Tominaga , Yeondae Kwon , Satoru Miyazaki

DNA マイクロアレイの遺伝子発現データから、真に生物学的に繋がりがある遺伝子群を選択的に検出するのは未だ難しい問題であり、今後も更なる発展が求められている。近年では大量の遺伝子発現データが個人レベルで取得可能となってきた。そこで本研究では、複数の比較実験データを統合したメタデータセットから得られる実験側で見た変動と遺伝子側で見た変動を利用し、両方向で発現変動を判定する、two-way AIC と …

IPSJ SIG Notes 2011-MPS-86(4), 1-6, 2011-11-24

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4

Expressions of the cytochrome P450 monooxygenase gene Cyp4g1 and its homolog in the prothoracic glands of the fruit fly Drosophila melanogaster (Diptera: Drosophilidae) and the silkworm Bombyx mori (Lepidoptera: Bombycidae)

Niwa Ryusuke , Sakudoh Takashi , Matsuya Takeshi , Namiki Toshiki , Kasai Shinji , Tomita Takashi , Kataoka Hiroshi , 丹羽隆介

… We identified Cyp4g1 by a microarray analysis to examine the expression levels of 86 predicted D. …

Applied entomology and zoology 46(4), 533-543, 2011-11

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5

Spatially selective hormonal control of RAP2.6L and ANAC071 transcription factors involved in tissue reunion in Arabidopsis

Asahina Masashi , Azuma Katsuya , Pitaksaringkarn Weerasak , Yamazaki Takashi , Mitsuda Nobutaka , Ohme-Takagi Masaru , Yamaguchi Shinjiro , Kamiya Yuji , Okada Kiyotaka , Nishimura Takeshi , Koshiba Tomokazu , Yokota Takao , Kamada Hiroshi , Satoh Shinobu , 朝比奈雅志 , 鎌田博 , 佐藤忍

… Microarray and quantitative RT-PCR analyses revealed that genes related to cell division, phytohormones, and transcription factors were expressed because of incision. …

Proceedings of the National Academy of Sciences of the United States of America 108(38), 16128-16132, 2011-09

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6

The improvement of riboflavin production in Ashbya gossypii via disparity mutagenesis and DNA microarray analysis

Park Enoch Y , Ito Yoko , Nariyama Masashi , Sugimoto Takashi , Lies Dwiarti , Kato Tatsuya

… DNA microarray analysis showed that purine and riboflavin biosynthetic pathways were upregulated, while pathways related to carbon source assimilation, energy generation, and glycolysis were downregulated. …

Applied microbiology and biotechnology 91(5), 1315-1326, 2011-09

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7

Rheological Properties of Growth-Arrested Fibroblast Cells under Serum Starvation Measured by Atomic Force Microscopy

Miyaoka Atsushi , Mizutani Yusuke , Tsuchiya Masahiro , Kawahara Koichi , Okajima Takaharu

… The rheological properties of growth-arrested and quiescent (G0 phase) mouse fibroblast cells under serum starvation were investigated by atomic force microscopy (AFM) with a microarray technique. …

Jpn J Appl Phys 50(8), 08LB16-08LB16-5, 2011-08-25

The Japan Society of Applied Physics
8

8.ビタミンB_6摂取に応答する大腸遺伝子発現のDNA microarray解析(第424回研究協議会研究発表要旨,ビタミンB研究委員会) [in Japanese]

加藤範久

Vitamins 85(8), 452, 2011-08-25

CiNii Fulltext PDF - Limited Ichushi Web
9

Gene and Protein Expression Analysis of Mesenchymal Stem Cells Derived From Rat Adipose Tissue and Bone Marrow

NAKANISHI Chiaki , NAGAYA Noritoshi , OHNISHI Shunsuke , YAMAHARA Kenichi , TAKABATAKE Shu , KONNO Tetsuo , HAYASHI Kenshi , KAWASHIRI Masa-aki , TSUBOKAWA Toshinari , YAMAGISHI Masakazu

Circulation journal : official journal of the Japanese Circulation Society 75(9), 2260-2268, 2011-08-25

References (33)
10

Rheological Properties of Growth-Arrested Fibroblast Cells under Serum Starvation Measured by Atomic Force Microscopy

Miyaoka Atsushi , Mizutani Yusuke , Tsuchiya Masahiro , Kawahara Koichi , Okajima Takaharu

… The rheological properties of growth-arrested and quiescent (G0 phase) mousefibroblast cells under serum starvation were investigated by atomic force microscopy(AFM) with a microarray technique. …

Japanese Journal of Applied Physics 50(8), 08-08, 2011-08

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11

Gene Network Analysis and Application [in Japanese]

ARAKI Hiromitsu , HURLEY Daniel , CRAMPIN Edmund , PRINT Cristin , KUHARA Satoru

… Gene network, which is inferred from microarray data by using reverse engineering algorithms, gives valuable information about the regulation of genes in the living cells under the certain conditions. …

Seibutsu Butsuri 51(4), 182-185, 2011-07-25

J-STAGE Ichushi Web CrossRef References (18)
12

Genome-wide integration on transcription factors, histone acetylation and gene expression reveals genes co-regulated by histone modification patterns.

Natsume-Kitatani Yayoi , Shiga Motoki , Mamitsuka Hiroshi

… We present the first genome-wide approach that captures GHUs by combining ChIP-chip with microarray datasets from Saccharomyces cerevisiae. … Furthermore, our method further suggested the recognition of acetylated H4 Lys16 being crucial to histone acetyltransferase ESA1, whose essential role is still under controversy, from a microarray dataset on ESA1 and its bypass suppressor mutants. …

PloS one 6(7), 2011-07

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13

Visualization of wounding-induced root-to-shoot communication in Arabidopsis

Sogabe Yusuke , Nakamura Haruna , Nakagawa Tomoyuki , Hasegawa Satoko , Asano Tomoya , Ohta Hiroyuki , Yamaguchi Kazuo , Mueller Martin J. , Kodama Hiroaki , Nishiuchi Takumi

It is known that wounding systemically activates the expression of various defense-related genes in plants. However, most studies of wound-induced systemic response are concerned with a leaf-toleaf re …

Plant Signaling and Behavior 6(7), 119-121, 2011-07

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14

Development of DNA point mutation detection methods using probe DNA-immobilized microbeads [in Japanese]

Hashimoto Masahiko , Tamai Yusuke , Tsukagoshi Kazuhiko

… The LDR products as a target obtained by the sequential PCR/LDR reactions can be analyzed in a variety of fashions such as microarray and slab gel electrophoresis. …

The science and engineering review of Doshisha University 52(2), 93-98, 2011-07

IR
15

Introduction and the future prospects of TIIMS(5)Genomic copy number aberrations and functional analysis using disease specific induced pluripotent stem (iPS) cells [in Japanese]

Yamamoto Toshiyuki/Shimojima Keiko

ポストゲノムの時代となり、ヒトの全ゲノムの一次配列が明らかになったことにより、全染色体領域のゲノムコピー数をマイクロアレイを用いて網羅的に解析することが可能となった。それにより、ゲノムコピー数がヒトによって異なる領域が存在することが明らかとなってきている。その一方、非常に微細なゲノム断片の欠失や重複が疾患の原因となっている場合があることがこの数年の間に次々と明らかになってきている。実際にアレイCG …

Journal of Tokyo Women's Medical College 81(3), 215-219, 2011-06-25

Ichushi Web
16

Introduction and the future prospects of TIIMS(1)Functional genomic study for free fatty acid receptors and drug discovery [in Japanese]

Hirasawa Akira/Tsujimoto Gozoh

遊離脂肪酸(FFAs)は栄養素として不可欠なだけでなく、多くの細胞機能の調節に関与している。これまでに遊離脂肪酸の取り込み、分解、輸送などに関わる多数のタンパク質が知られているが、中でもPPARsを含む核内受容体は、生理学的・病態生理学的な状態において恒常性を維持する、脂肪酸"センサー" である。しかし、これらのタンパク質で全ての生物学的現象が説明できるわけではなく、細胞表面受容体の存在の可能性も …

Journal of Tokyo Women's Medical College 81(3), 190-197, 2011-06-25

Ichushi Web
17

Search of miRN As critical for medulloblastoma formation using MiRaGE method

TAGUCHI Y-H. , YASUDA JUN

… Expression profile of mRNA/miRNA is measured for tissues from neonatal and adult mice (6 days and 30 days after birth: P6 and P30, respectively), and medulloblastomas (2-3 months old: MB) with Agilent microarray is analyzed by MiRaGE method. … The obtained list is biologically reasonable, possibly due to accuracy of Agilent microarray measurement, thus we conclude that MiRaGE method is useful to investigate tissue formation processes, too. …

IEICE technical report. Neurocomputing 111(96), 21-26, 2011-06-16

CiNii Fulltext PDF - Limited
18

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1.

Maekawa Momoko , Yamaguchi Kei , Nakamura Tomonori , Shibukawa Ran , Kodanaka Ikumi , Ichisaka Tomoko , Kawamura Yoshifumi , Mochizuki Hiromi , Goshima Naoki , Yamanaka Shinya

… DNA microarray analyses show that Glis1 promotes multiple pro-reprogramming pathways, including Myc, Nanog, Lin28, Wnt, Essrb and the mesenchymal-epithelial transition. …

Nature 474(7350), 225-229, 2011-06-09

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19

Intracystic Papillary Carcinoma of Breast Harbors Significant Genomic Alteration Compared with Intracystic Papilloma: Genome-wide Copy Number and LOH Analysis Using High-Density Single-Nucleotide Polymorphism Microarrays.

Oikawa Masahiro , Nagayasu Takeshi , Yano Hiroshi , Hayashi Tomayoshi , Abe Kuniko , Kinoshita Akira , Yoshiura Koh-Ichiro

… Results: Quality control (QC) call rate, which is an index measuring the quality of a SNP microarray experiment, ranged from 70.75% to 91.93%, mean 80.72%. …

The Breast Journal 17(4), 427-430, 2011-06-09

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20

Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury

HWANG Gi-Wook , LEE Jin-Yong , RYOKE Katsunori , MATSUYAMA Fujio , KIM Jong-Mu , TAKAHASHI Tsutomu , NAGANUMA Akira

… To elucidate the molecular mechanism involved in methylmercury-induced cerebellar disorder, we performed DNA microarray analysis of the cerebellum of methylmercury-treated mice. …

The Journal of Toxicological Sciences 36(3), 389-391, 2011-06-01

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