Search Results:　 1-20 of 165

1

Genotoxicity detection of five medicinal plants in Nigeria

HONG Chang-Eui , LYU Su-Yun

… To evaluate the bacterial reverse mutation of these five medicinal plants, the in vitro Ames test using Salmonella typhimurium TA98, TA100, TA1535, and TA1537, and Escherichia coli WP2uvrA, with or without the addition of S9 mixture was performed. …

The Journal of Toxicological Sciences 36(1), 87-93, 2011-02-01

J-STAGE Ichushi Web CrossRef References (24)
2

Determination of 3,6-Dinitrobenzo[e]pyrene in Tea Leaves as a Possible Exposure Source and in Human Hair as a Biomarker Using a Two-dimensional HPLC System

Hasei Tomohiro , Ohno Atsumi , Tsukuda Rie , Inoue Tatsuro , Watanabe Tetsushi

… 3,6-Dinitrobenzo[e]pyrene (DNBeP) is an extremely strong mutagen in Salmonella Typhimurium TA98 without a mammalian metabolic system (S9 mix). …

JOURNAL OF HEALTH SCIENCE 57(1), 53-59, 2011

J-STAGE CrossRef
3

Mutagenic potentials of Amberlite XAD-2-resin extracts obtained from river and drinking waters in the Northwest district of Chiba, Japan

KANNO Ayako , NISHI Iwaki , KISHI Tomohiro , KAWAKAMI Tsuyoshi , TAKAHASHI Yasuo , ONODERA Sukeo

… The extracts from the river water were shown to be mutagenic in Salmonella typhimurium TA98 (a flameshift mutagen) without S9 mix, with higher mutagenic responses in summer and early fall seasons. … While the drinking water extracts exhibited weak mutagenicity in both the TA98 and TA100 strains (a base-pair substitution mutagen) without S9 mix, with high mutagenic responses in fall and early winter seasons. …

The Journal of Toxicological Sciences 35(6), 817-826, 2010-12-01

J-STAGE Ichushi Web CrossRef References (38)
4

Mutagenicity of octane and tetrasodium pyrophosphate in bacterial reverse mutation (Ames) test

KIM Soo-Jin , RIM Kyung-Taek , KIM Hyeon-Yeong , YANG Jeong-Sun

… In this test, treatment of 2 chemicals at each five dose did not induce mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA1537, and in Escherichia coli WP2uvrA with and without metabolic activation. …

The Journal of Toxicological Sciences 35(4), 555-562, 2010-08-01

J-STAGE Ichushi Web CrossRef References (31)
5

Mutagenic activation and detoxification of benzo[a]pyrene in vitro by hepatic cytochrome P450 1A1 and phase II enzymes in three meat-producing animals

Darwish W. , Ikenaka Y. , Eldaly E. , Ishizuka M.

… In the Ames Salmonella typhimurium TA98 assay, the liver microsomes of all examined animals mutagenically activated benzo[a]pyrene, an ideal promutagens, in terms of production of histidine-independent revertant colonies. …

Food and Chemical Toxicology 48(8-9), 2526-2531, 2010-08-00

IR CrossRef
6

In vitro and in vivo evaluation of mutagenicity of fucoxanthin (FX) and its metabolite fucoxanthinol (FXOH)

Beppu Fumiaki , Niwano Yoshimi , Sato Emiko , Kohno Masahiro , Tsukui Takayuki , Hosokawa Masashi , Miyashita Kazuo

… In in vitro Ames test, bacterial reverse mutation was examined by using Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, and Escherichia coli WP2uvrA/pKM101, with or without metabolic activation by S9 mix in the preincubation method, and mutagenicity of FXOH was found to be negative in all cases. …

Journal of toxicological sciences 34(6), 693-698, 2009-12-01

CiNii Fulltext PDF - Open Access J-STAGE Ichushi Web CrossRef References (21) Cited by (1)
7

Improvement and Evaluation of High Throughput Fluctuation Ames Test Using 384-well Plate with Salmonella typhimurium TA100 and TA98

SUI Hajime , KAWAKAMI Kumiko , SAKURAI Noriko , HARA Takumi , NOHMI Takehiko

Genes and environment 31(2), 47-55, 2009-05-20

Ichushi Web References (13)
8

Mutagenicity of water-soluble ZnO nanoparticles in Ames test

Yoshida Rie , Kitamura Daisuke , Maenosono Shinya

… A mutagenicity test was conducted on water-soluble ZnO nanoparticles capped with tetramethylammonium hydroxide in a bacterial reverse mutation assay using Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, and Escherichia coli strain WP2uvrA－, with and without metabolic activation by S9 mix in the preincubation method. …

Journal of toxicological sciences 34(1), 119-122, 2009-02-01

CiNii Fulltext PDF - Open Access IR J-STAGE Ichushi Web CrossRef References (13)
9

Determination of 3,6-dinitrobenzo[e]pyrene in Surface Soil and Airborne Particles, and Its Possible Sources, Diesel Particles and Incinerator Dusts

Hasei Tomohiro , Watanabe Tetsushi , Endo Osamu , Sugita Kazutoshi , Asanoma Masaharu , Goto Sumio , Hirayama Teruhisa

… 3,6-DNBeP was detected in all surface soil samples, and the mutagenic contribution ratio of 3,6-DNBeP to the mutagenicity of the soil extracts toward Salmonella (S.) typhimurium TA98 was 17.3% on average. …

JOURNAL OF HEALTH SCIENCE 55(4), 567-577, 2009

J-STAGE CrossRef
10

Nicotine, Tar, and Mutagenicity of Mainstream Smoke Generated by Machine Smoking with International Organization for Standardization and Health Canada Intense Regimens of Major Japanese Cigarette Brands

Endo Osamu , Matsumoto Mariko , Inaba Yohei , Sugita Kazutoshi , Nakajima Daisuke , Goto Sumio , Ogata Hiromitsu , Suzuki Gen

… One of the three lots of each MSS condensate was also resolved in dimethylsulfoxide and investigated by Ames preincubation assay using Salmonella typhimurium TA100, TA98, and YG1024 strains with and without metabolic activation (rat liver S9 mix). … Mutagenicity was mainly observed in TA98 and YG1024 with metabolic activation. …

JOURNAL OF HEALTH SCIENCE 55(3), 421-427, 2009

J-STAGE Ichushi Web CrossRef Cited by (1)
11

Urinary Mutagenicity in Chemical Laboratory Workers Exposed to Solvents

VARELLA Soraya D. , RAMPAZO Raquel A. , VARANDA Eliana A.

… Several strains of Salmonella typhimurium (TA100, TA98, TA97a, TA1535, YG1024) should be used to assess mutagenic susceptibilities among workers exposed to organic solvents. … typhimurium strains TA100 and YG1024, with and without metabolic activation. … The mutagenic activity, measured in Salmonella typhimurium YG1024 with S9 mix, was significantly greater in urine from workers than from controls (p≤0.05). …

Journal of occupational health 50(5), 415-422, 2008-09-00

CiNii Fulltext PDF - Open Access Ichushi Web References (43)
12

Safety Evaluation of Tsubaki (Camellia japonica) Leaves Extract [in Japanese]

KUBA Megumi , TSUHA Kazuyo , HIROSE YASUMOTO Mina , TSUHA Keiko , YASUMOTO Takeshi

… 出物投与群に死亡例はなく，一般状態，体重，摂餌量，尿検査，血液学的検査，血液生化学的検査，器官重量，解剖検査および病理組織学的検査で異常は認められなかった．以上のことから，本実験条件ではツバキ葉抽出物500mg/kgと2000mg/kgのいずれにおいても経口摂取による毒性は検出されなかった．<BR>さらに，ツバキ葉抽出物の遺伝子突然変異誘発性の有無を，<I>Salmonella typhimurium</I> …

Nippon Shokuhin Kagaku Kogaku Kaishi 55(8), 379-382, 2008-08-15

J-STAGE CrossRef References (10) Cited by (1)
13

MUTAGENICITY OF WATER-SOLUBLE FePt NANOPARTICLES IN AMES TEST

MAENOSONO Shinya , SUZUKI Toshimasa , SAITA Soichiro

… A mutagenicity test was conducted on water-soluble FePt nanoparticles capped with tetramethylammonium hydroxide in a bacterial reverse mutation assay using Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, and Escherichia coli strain WP2uvrA/pKM101, with and without metabolic activation by S9 mix in the preincubation method. …

Journal of toxicological sciences 32(5), 575-579, 2007-12-14

CiNii Fulltext PDF - Open Access IR J-STAGE Ichushi Web CrossRef References (17) Cited by (1)
14

Evaluation of mutagenicity of complex magnetic fields with static and extremely low frequency components [in Japanese]

IKEHATA Masateru , YOSHIE Saschiko , SUZUKI Yukihisa , TAKI Masao , HAYAKAWA Toshio

本研究では,定常磁界と極低周波磁界に着目し,これらの磁界を重畳させた曝露条件を実現する曝露装置の開発を行った.さらに,その変異原性について,エイムステストおよび出芽酵母での変異原検出系を用いて,定常磁界5T,50Hz変動磁界1mTをそれぞれの磁界の最大値として検討を行った.その結果,エイムステストにおける点突然変異の発生頻度,および出芽酵母における点突然変異の発生頻度には磁界曝露群と非曝露群の間に …

IEICE technical report. Electromagnetic compatibility 107(310), 57-61, 2007-11-08

CiNii Fulltext PDF - Subscription References (6)
15

Mutagenic Activity of a Mixture of Heterocyclic Amines at Doses below the Biological Threshold Level of Each

Ohta Toshihiro

… The combined mutagenic effects of six heterocyclic amines (Trp-P-1, Trp-P-2, Glu-P-1, Glu-P-2, MelQ, and IQ) at doses below the biological threshold level of each were investigated in the reverse mutation assay with Salmonella typhimurium. … The lowest mutagenic doses of heterocyclic amines in TA1978P (hisD3052, rfa/pKM101) were 40 to 200 times the lowest mutagenic doses in TA98 (hisD3052, rfa, uvrB/pKM101), a strain deficient in nucleotide excision repair. …

Genes and environment : the official journal of the Japanese Environmental Mutagen Society 28(4), 181-184, 2006-11-30

CiNii Fulltext PDF - Open Access Ichushi Web References (17)
16

Identification of 1,3,6-Trinitropyrene as a Major Mutagen in Organic Extracts of Surface Soil from Nagoya City, Japan

Takahashi Kazuhiko , Asanoma Masaharu , Yoshida Satoshi , Gao Ning , Mori Haruyuki , Horibe Tomomi , Watanabe Tetsushi , Hirayama Teruhisa , Nukaya Haruo , Mizutani Takaharu

… An organic extract from surface soil collected at a park in Nagoya, Aichi prefecture, which showed extremely high mutagenicity in Salmonella typhimurium TA98 in the absence of a mammalian metabolic system (S9 mix), was investigated to identify the major mutagens. … typhimurium was extremely high, in that it induced 65,500 revertants/nmol in TA98, without S9 mix. …

Genes and environment : the official journal of the Japanese Environmental Mutagen Society 28(4), 160-166, 2006-11-30

CiNii Fulltext PDF - Open Access Ichushi Web References (31)
17

Mutagenic Activity of Atmospheric Ultrafine Particles at a Roadside Site and a Suburban Site

Kawanaka Youhei , Matsumoto Emiko , Wang Ning , Tsuchiya Yoshiteru , Yun Sun-Ja , Jiang Zhao Wu , Sakamoto Kazuhiko

… The mutagenic activity of the size-fractionated PM was determined by the Ames test using Salmonella typhimurium strain TA98 without metabolic activation (S9). …

Journal of health science 52(4), 352-357, 2006-08-01

CiNii Fulltext PDF - Open Access J-STAGE Ichushi Web CrossRef References (26)
18

Development of a Bacterial Hyper-sensitive Tester Strain for Specific Detection of the Genotoxicity of Polycyclic Aromatic Hydrocarbons

Yamada Masami , Matsui Keiko , Nohmi Takehiko

… To sensitively detect the genotoxicity of PAHs in complex mixtures extracted from environmental pollutants, Salmonella enterica serovar Typhimurium (S. … typhimurium) strain YG5161 is engineered by introduction of plasmid pYG768 carrying the dinB gene encoding Escherichia coli DNA polymerase IV into standard Ames tester strain S. … typhimurium TA1538 (Matsui et al., DNA Repair in press). …

Genes and environment : the official journal of the Japanese Environmental Mutagen Society 28(1), 23-30, 2006-02-28

CiNii Fulltext PDF - Open Access Ichushi Web References (34) Cited by (2)
19

Mutagenicity of Surface Soils in Urban Areas of Aichi Prefecture, Japan, and Bangkok, Thailand

Watanabe Tetsushi , Kusamran Wannee R. , Asanoma Masaharu , Tepsuwan Anong , Tantasri Nopsarun , Meesiripan Nuntana , Hasei Tomohiro , Murahashi Tsuyoshi , Hirayama Teruhisa , Wakabayashi Keiji

… To clarify the contamination levels of surface soil with mutagens in urban areas of Aichi prefecture, Japan, and Bangkok, Thailand, 60 and 67 surface soil samples were collected in Aichi and Bangkok, respectively, and mutagenicities of the organic extracts from these soil samples were examined in the Ames assay using Salmonella typhimurium (S. … typhimurium) TA98 and TA100 with and without a mammalian metabolic system (S9 mix). …

Journal of health science 51(6), 645-657, 2005-12-01

CiNii Fulltext PDF - Open Access J-STAGE Ichushi Web CrossRef References (33) Cited by (1)
20

Antimutagenicity and Cytotoxicity of the Constituents from the Aerial Parts of Rumex acetosa(Pharmacognosy)

LEE Nam Jae , CHOI Jung Hyun , KOO Byung Soo , RYU Shi Yong , HAN Yeong Hwan , LEE Seung Il , LEE Dong Ung

… for the first time from the aerial parts of Rumex acetosa (Polygonaceae), a Korean and a Japanese medicinal plant, and two synthetic derivatives were examined for their cytotoxicities against five cultured human tumor cell lines, i.e. A549 (non-small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system) and HCY15 (colon), using the Sulfrhodamine-B method in vitro and antimutagenic activities by Ames test with Salmonella typhimurium TA98 and TA100 and SOS chromotest with …

Biological & pharmaceutical bulletin 28(11), 2158-2161, 2005-11-01

CiNii Fulltext PDF - Open Access J-STAGE Ichushi Web CrossRef References (27)

Search Results:　 1-20 of 165

Related Authors

Related Journals

Search Results: 1-20 of 165

Related Authors

Related Journals

Search Results:　 1-20 of 165