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Protective Effect of Lignans against Sepsis from the Roots of Saururus chinensis(Pharmacognosy)
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SEO Chang-Seob
,
LEE Yeun-Kyung
,
KIM Young-Jin
,
JUNG Jun-Sub
,
JAHNG Yurngdong
,
CHANG Hyun-Wook
,
SONG Dong-Keun
,
SON Jong-Keun
… In the course of isolating preventive agents from sepsis based on the in vivo assay model from the EtOAc extract of the roots of Saumrus chinensis, twelve lignans, sarisan (1), eryrthro-austrobailignan-6 (2), meso-dihydroguaiaretic acid (3), saucerneol B (4), manassantin B (5), manassantin A (6), rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan (7), (+)-saururinone (8), sauchinone (9), sauchinone B (10), nectandrin B (11) and machilin D (12), were isolated. …
Biological & pharmaceutical bulletin 31(3), 523-526, 2008-03-01
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