CiNii Articles - Therapeutic angiogenesis

1

GEP100-Arf6-AMAP1-Cortactin Pathway Frequently Used in Cancer Invasion Is Activated by VEGFR2 to Promote Angiogenesis

Hashimoto Ari , Hashimoto Shigeru , Ando Ryo , Noda Kosuke , Ogawa Eiji , Kotani Hirokazu , Hirose Mayumi , Menju Toshi , Morishige Masaki , Manabe Toshiaki , Toda Yoshinobu , Ishida Susumu , Sabe Hisataka

… Angiogenesis and cancer invasiveness greatly contribute to cancer malignancy. … Arf6 is highly expressed also in human umbilical vein endothelial cells (HUVECs) and is implicated in angiogenesis. … We demonstrate that the same GEP100-Arf6-AMAP1-cortactin pathway is essential for angiogenesis activities, including cell migration and tubular formation, as well as for the enhancement of cell permeability and VE-cadherin endocytosis of VEGF-stimulated HUVECs. …

PLoS One 6(8), e23359, 2011-08-15

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2

Therapeutic angiogenesis for the treatment of ischemic heart disease [in Japanese]

小山博之

日本臨床 69 (1010増刊9), 316-319, 2011-11
3

Clinical features of cases with critical limb ischemia who responded to treatment with autologous mononuclear cell transplantation for therapeutic angiogenesis [in Japanese]

西成真琴 , 青山直善 , 大谷慎一 [他]

The journal of Japanese Society of Limb Salvage and Podiatric Medicine 3(3), 121-128, 2011
4

Therapeutic angiogenesis by cell transplantation [in Japanese]

室原豊明

綜合臨床 60(10), 2103-2110, 2011-10

Ichushi Web
5

Therapeutic angiogenesis for coronary artery [in Japanese]

谷山義明 , 東純哉 , 岩林正明 [他]

Japanese journal of clinical medicine 69(-) (1006), 74-79, 2011-09

Ichushi Web
6

幹細胞筋肉内投与による足救済 (特集形成外科領域の臨床再生医学 update) [in Japanese]

宮本正章 , 水野博司

Pepars (50), 39-45, 2011-02

Ichushi Web
7

Novel therapeutic angiogenesis for ischemic limb using biodegradable gelatin hydrogel [in Japanese]

丸井晃 , 田畑泰彦 , 柳茂樹 [他]

Regenerative medicine 10(1), 37-44,87, 2011-02
8

Pathological Role of Apelin in Angiogenic Eye Disease

KASAI Atsushi

… Progression of ischemic retinal diseases, such as diabetic retinopathy, is closely associated with pathological retinal angiogenesis mainly induced by vascular endothelial growth factor (VEGF). … Since many factors are involved in angiogenesis, it is reasonable to seek new therapeutic target molecules in pathological retinal angiogenesis. …

YAKUGAKU ZASSHI 131(8), 1201-1206, 2011

J-STAGE CrossRef
9

Pathophysiological Response to Hypoxia — From the Molecular Mechanisms of Malady to Drug Discovery:Epigenetic Regulation of the Hypoxic Response via Hypoxia-Inducible Factor and Histone Modifying Enzymes

Mimura Imari , Tanaka Tetsuhiro , Wada Youichiro , Kodama Tatsuhiko , Nangaku Masaomi

… The hypoxia response regulated primarily by hypoxia-inducible factor (HIF) influences metabolism, cell survival, and angiogenesis to maintain biological homeostasis. … Recent studies have demonstrated that histone modifiers play important roles in the hypoxic environment such as that in cancer cells and that they may become new therapeutic targets for cancer patients. …

Journal of Pharmacological Sciences 115(4), 453-458, 2011

J-STAGE CrossRef
10

Pathophysiological Response to Hypoxia — From the Molecular Mechanisms of Malady to Drug Discovery:Drug Discovery for Targeting the Tumor Microenvironment

Nagasawa Hideko

… However, exploiting such a cumbersome tumor microenvironment for cancer treatment could provide tumor-specific therapeutic approaches. … In particular, hypoxia is now considered a fundamentally important characteristic of the tumor microenvironment in which hypoxia inducible factor (HIF)-1–mediated gene regulation is considered essential for angiogenesis and tumor development. …

Journal of Pharmacological Sciences 115(4), 446-452, 2011

J-STAGE CrossRef
11

Protein Kinase B (Akt) Promotes Pathological Angiogenesis in Murine Model of Oxygen-Induced Retinopathy

Wang Peng , Tian Xiao-Feng , Rong Jun-Bo , Liu Dan , Yi Guo-Guo , Tan Qian

… However, the vivo roles and effectors of Akt in retinal angiogenesis are not explicitly clear. … These results indicate that Akt play a critical role in the pathological process (vessels loss and neovascularization) of mouse model of oxygen-induced retinopathy, which may provide a valubale therapeutic tool for ischemic-induced retinal diseases. …

ACTA HISTOCHEMICA ET CYTOCHEMICA advpub(0), 1104190108, 2011

J-STAGE CrossRef
12

Thalidomide Prevents the Progression of Peritoneal Fibrosis in Mice

Arai Hideyuki , Furusu Akira , Nishino Tomoya , Obata Yoko , Nakazawa Yuka , Nakazawa Masayuki , Hirose Misaki , Abe Katsushige , Koji Takehiko , Kohno Shigeru

… Thalidomide is clinically recognized as a therapeutic agent for multiple myeloma and has been known to exert anti-angiogenic actions. … Recent studies have suggested the involvement of angiogenesis in the progression of peritoneal fibrosis. … Thalidomide treatment significantly ameliorated submesothelial thickening and angiogenesis, and decreased numbers of PCNA- and VEGF-expressing cells, myofibroblasts, and TGF-β-positive cells. …

ACTA HISTOCHEMICA ET CYTOCHEMICA advpub(0), 1104190104, 2011

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13

Cardiogenesis From Human Embryonic Stem Cells : Mechanisms and Applications

MIGNONE John L. , KREUTZIGER Kareen L. , PAIGE Sharon L. , MURRY Charles E.

… Over the past decade, the ability to culture and differentiate human embryonic stem cells (ESCs) has offered researchers a novel therapeutic that may, for the first time, repair regions of the damaged heart. …

Circulation Journal 74(12), 2517-2526, 2010-11-25

J-STAGE Ichushi Web CrossRef References (44) Cited by (2)
14

A Pathological Role of Semaphorin3E in Postnatal Angiogenesis and Its Implication for Therapeutic Angiogenesis [in Japanese]

MORIYA Junji , MINAMINO Tohru , KOMURO Issei

血管 33(2), 45-48, 2010-07-23

Ichushi Web References (8)
15

Establishment of a Novel Strategy for Therapeutic Angiogenesis [in Japanese]

MORIYA Junji , MINAMINO Tohru

脈管学 : 日本脈管学会機関誌 : the journal of Japanese College of Angiology 50(3), 351-355, 2010-06-25

References (11)
16

A Pathological Role of Semaphorin3E in Postnatal Angiogenesis and Its Implication for Therapeutic Angiogenesis [in Japanese]

MORIYA Junji , MINAMINO Tohru , TATENO Kaoru , KOMURO Issei

脈管学 : 日本脈管学会機関誌 : the journal of Japanese College of Angiology 50(3), 343-349, 2010-06-25

References (8)
17

Selective and Sustained Delivery of Basic Fibroblast Growth Factor (bFGF) for Treatment of Peripheral Arterial Disease : Results of a Phase I Trial [in Japanese]

HASHIMOTO Takuya , KOYAMA Hiroyuki , HOSAKA Akihiro , MIYATA Tetsuro , TAKATO Tsuyoshi , TABATA Yasuhiko

脈管学 : 日本脈管学会機関誌 : the journal of Japanese College of Angiology 50(3), 315-322, 2010-06-25

References (6)
18

Therapeutic angiogenesis in patients with systemic sclerosis by autologous transplantation of bone-marrow-derived cells

ISHIGATSUBO Yoshiaki , IHATA Atsushi , KOBAYASHI Hiroshi , HAMA Maasa , KIRINO Yohei , UEDA Atsuhisa , TAKENO Mitsuhiro , SHIRAI Akira , OHNO Shigeru

Modern rheumatology 20(3), 263-272, 2010-06-01

Ichushi Web References (20)
19

Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice

Qia Xun , Okamoto Yasuo , Murakawa Tomomi , Wang Fei , Oyama Osamu , Ohkawa Ryunosuke , Yoshioka Kazuaki , Du Wa , Sugimoto Naotoshi , Yatomi Yutaka , Takuwa Noriko , Takuwa Yoh

… Therapeutic angiogenesis is a promising strategy for treating ischemia. … The lysophospholipid mediator sphingosine-1-phosphate (S1P) acts on vascular endothelial cells to stimulate migration and tube formation, and plays the critical role in developmental angiogenesis. …

European Journal of Pharmacology 634(1-3), 121-131, 2010-05

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20

Development of hydroxyapatite-nanocrystal-coated microspheres for therapeutic angiogenesis using cell transplantation [in Japanese]

OKADA Masahiro , FUKUMOTO Shinya , MIMA Yohei , FUJII Syuji , FURUZONO Tsutomu

Journal of Japanese Society for Biomaterials 28(2), 88-95, 2010-04-28

Ichushi Web References (33)

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