検索結果:　 71件中 1-20 を表示

1

Molecular Cloning of LIM Homeodomain Transcription Factor Lhx2 as a Transcription Factor of Porcine Follicle-Stimulating Hormone Beta Subunit (FSHβ) Gene

KATO Takako , ISHIKAWA Akio , YOSHIDA Saishu , SANO Yoshiya , KITAHARA Kousuke , NAKAYAMA Michie , SUSA Takao , KATO Yukio

… We cloned the LIM-homeodomain protein LHX2 as a transcription factor for the porcine follicle-stimulating hormone β subunit gene (Fshβ) by the Yeast One-Hybrid Cloning System using the upstream region of -852/-746 bases (b) from the transcription start site, called Fd2, as a bait sequence. …

Journal of Reproduction and Development advpub(0), 1111240419, 2011

J-STAGE CrossRef
2

Promoter and Terminator Analysis of 40-kDa Outer Membrane Gene (hbp35) in Porphyromonas gingivalis 381

Tanaka Hideki , Hiratsuka Koichi , Abiko Yoshimitsu

… A possible promoter sequence (TTGCAG in the -35 region and TATTTT in the -10 region), which were nearly identical to the predicted promoter sequences, were found upstream of the start codon (ATG). … The transcription start site (+1) was predicted to be located 53 nt upstream from the translation start codon. …

International Journal of Oral-Medical Sciences 10(2), 96-102, 2011

J-STAGE CrossRef
3

Divergence of CpG island promoters : A consequence or cause of evolution?

SHARIF Jafar , ENDO Takaho A. , TOYODA Tetsuro , KOSEKI Haruhiko

Development, growth & differentiation 52(6), 545-554, 2010-08-01

医中誌参考文献41件
4

Comprehensive gene expression analysis of 5'-end of mRNA identified novel intronic transcripts associated with hepatocellular carcinoma

Hodo Yuji , Hashimoto Shin-ichi , Honda Masao , Yamashita Taro , Suzuki Yutaka , Sugano Sumio , Kaneko Shuichi , Matsushima Kouji

… To elucidate the molecular feature of human hepatocellular carcinoma (HCC), we performed 5'-end serial analysis of gene expression (5'SAGE), which allows genome-wide identification of transcription start sites in addition to quantification of mRNA transcripts. … The present results indicate that the transcription initiation of a subset of genes may be distinctively altered in HCC, which may suggest the utility of intronic RNAs as surrogate tumor markers. …

Genomics 95(4), 217-223, 2010-04

機関リポジトリ CrossRef
5

Identification of a high incidence region for retroviral vector integration near exon 1 of the LMO2 locus

Yamada Koichiro , Tsukahara Tomonori , Yoshino Kazuhisa , Kojima Katsuhiko , Agawa Hideyuki , Yamashita Yuki , Amano Yuji , Hatta Mariko , Matsuzaki Yasunori , Kurotori Naoki , Wakui Keiko , Fukushima Yoshimitsu , Osada Ryosuke , Shiozawa Tanri , Sakashita Kazuo , Koike Kenichi , Kumaki Satoru , Tanaka Nobuyuki , Takeshita Toshikazu

… We identified a high incidence region (HIR) of vector integration using PCR techniques in the upstream region close to the LMO2 transcription start site in the TPA-Mat T cell line. … One of the X-linked severe combined immunodeficiency (X-SCID) patients that developed leukemia after gene therapy had a vector integration site in this HIR. …

Retrovirology 6, 2009-09-02

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6

In Silico Identification of Short Nucleotide Sequences Associated with Gene Expression of Pollen Development in Rice

MIHARA Motohiro , ITOH Takeshi , IZAWA Takeshi

Plant and cell physiology 49(10), 1451-1464, 2008-10-01

参考文献30件被引用文献2件
7

Identification and Characterization of Mouse Type II Platelet-Derived Growth Factor Receptor α Transcript

MINATO Yusuke , NIHEI Yoshiaki , KODAMA Yuki , TASHIRO Etsu , KANAI Mai , IMOTO Masaya

… In this study, we determined the nucleotide sequence of the mouse type II PDGF receptor α mRNA and found that the expression of this transcript was regulated by E2F-1 through an E2F-1-responsive sequence located +711/+718 downstream of the transcription start site of the type I transcript. …

Bioscience, biotechnology, and biochemistry 72(3), 759-766, 2008-03-23

J-STAGE 医中誌 CrossRef 参考文献21件
8

Prediction of p53 target genes based on integrative analysis of chromatin immunoprecipitated and sequenced tags，by using Galaxy，a web-based interactive platform for large-scale genome analysis

Hiroaki Mita , Yasushi Sasaki , Hiromu Suzuki , Masashi Idogawa , Lisa Kashima , Naoki Anbo , Hirofumi Akashi , Haruyuki Tatsumi , Minoru Toyota

… Chromatin immunoprecipitation (ChIP) followed by sequencing of immunoprecipitated DNA fragments is the high throughput method for identifying transcription factor binding sites. … Another search for p53 target genes, which focused on PET clusters located within 50-kb flanking regions of transcription start sites of genes, identified 278 of Refseq genes, 79 of non-coding RNAs and 5 of microRNAs as p53 targets which included lots of known validated targets. …

2008

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9

30.イネのジャスモン酸応答性転写因子RERJ1に発現制御されるchitinase遺伝子のプロモーター解析(口頭発表)

宮本皓司 , 岡田憲典 , 鈴村孝史 , 大谷敬 , 桐渕協子 , 長村吉晃 , 澁谷直人 , 野尻秀昭 , 山根久和

… RERJ1 that encodes a bHLH transcription factor was isolated as a JA-responsive gene from rice suspension cells. … We conducted the deletion analysis of the chitinase promoter regions located from -2415 to -265 bp upstream of the translation start site. … Indeed, the region contains three E-box elements, which are putative binding sites for bHLH transcription factors. …

植物化学調節学会研究発表記録集 (42), 43, 2007-10-05

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10

ケモカインレセプターCXCR4を標的とした口腔癌に対するリンパ節転移抑制療法の開発

富塚佳史

… By using several deletion constructs against CXCR4 promoters, the minimal vesnarinone-responsive element in the CXCR4 promoter region at -300 to -167 relative to the transcription start site was identified. … Moreover, using a cDNA microarray method, I identified a transcription factor, krtippel-like factor 2 (KLF2), as a novel vesnarinone-responsive molecule which was able to bind to this region. …

四国歯学会雑誌 20(1), 155-175, 2007-06

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11

Characterization of the Promoter of the Mouse Preproorexin Gene

KATO Haruno , HOSODA Hiroshi , FUKUDA Toru , MASUSHIGE Shoichi , KIDA Satoshi

… We determined that the transcription start site (+1) is located 96 nucleotides upstream of the initiation codon. … The start site region contained consensus sequences corresponding to the transcription initiator and TATA box. …

Bioscience, biotechnology, and biochemistry 71(3), 840-843, 2007-03-23

J-STAGE 医中誌 CrossRef 参考文献15件
12

S2d2-4 New complexities of transcription start site usage in mammals(S2-d2: "Bioinformatics of Transcriptional Regulation",Symposia,Abstract,Meeting Program of EABS & BSJ 2006)

Frith Martin C. , Kawaji Hideya , Sandelin Albin , Ponjavic Jasmina , Carninci Piero , Hayashizaki Yoshihide

生物物理 46(SUPPLEMENT_2), S129, 2006-10-01

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13

Identification of cis-Acting Regions That Contribute to Neuron-Specific Expression of the GAP-43 Gene

TAKAHASHI Mikio , SATO Yoshitaka , NAKAGAMI Yuki , MIYAKE Katsuhide , IIJIMA Shinji

… There are two transcription start sites in the growth-associated protein 43 (GAP-43) promoter, and several repressive elements have been reported in the control region. … But the repressive effects have been analyzed only for the distal transcription start site. …

Bioscience, biotechnology, and biochemistry 70(6), 1492-1495, 2006-06-23

J-STAGE CrossRef 参考文献14件
14

クローン牛胎児の組織、およびドナー細胞のDNAメチル化プロフィール

KREMENSKOY Maksym , KREMENSKA Yuliya , 鈴木雅子 , 今井敬 , 高橋清也 , 橋爪一善 , 八木慎太郎 , 塩田邦郎

… Methylation of DNA in CpG islands plays an important role during fetal development and differentiation because CpG islands are preferentially located in upstream regions of mammalian genomic DNA, including the transcription start site of housekeeping genes and are also associated with tissue-specific genes. …

The Journal of reproduction and development 52(2), 259-266, 2006-04-01

J-STAGE 医中誌 CrossRef 参考文献41件被引用文献3件
15

GATA-4 Gene Organization and Analysis of Its Promoter(Biochemistry)

OHARA Yasunori , ATARASHI Takeshi , ISHIBASHI Takuya , OHASHI-KOBAYASHI Ayako , MAEDA Masatomo

… The transcriptional start site of the GATA-4 gene is essentially the same in rat heart, stomach and testis, and in cultured cells expressing GATA-4 such as TM3, TM4, I-10 and P19.CL6 cells. … The GC-boxes and E-box located in the several tens of base pairs upstream of the transcriptional start sites of the GATA-4 gene were found to be critical for its promoter activity in these cells, consistent with the mode of transcription characteristics of the TATA-less promoter. …

Biological & pharmaceutical bulletin 29(3), 410-419, 2006-03-01

CiNii PDF - オープンアクセス J-STAGE 医中誌 CrossRef 参考文献76件被引用文献1件
16

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs-8118 and -7750 upstream from the transcription start site

RAUM JC

Mol Cell Biol 26, 5735-5743, 2006

CrossRef 被引用文献2件
17

Transcription Regulatory Complex Including YB-1 Controls Expression of Mouse Matrix Metalloproteinase-2 Gene in NIH3T3 Cells(Molecular and Cell Biology)

MATSUMOTO Kenichi , ABIKO Shun , ARIGA Hiroyoshi

… The deletion analysis indicated that the proximal 327-bp sequence from nucleotide positions -313 to +14 relative to the transcription start site is essential for minimal promoter activity and that a 10-bp sequence of the promoter at positions -939 to -930 is required for high expression level of the MMP-2 gene. …

Biological & pharmaceutical bulletin 28(8), 1500-1504, 2005-08-01

CiNii PDF - オープンアクセス J-STAGE 医中誌 CrossRef 参考文献20件
18

Molecular Cloning and Analysis of the 5'-Flanking Region of the Human Thiamin Pyrophosphokinase Gene

ONOZUKA Mari , KONNO Hiroyuki , AKAJI Kenichi , NISHINO Hoyoku , NOSAKA Kazuto

… Truncation analysis using transiently transfected HepG2 cells revealed the minimal region required for basal activity of the hTPK1 promoter, which was encoded in a sequence between -105 and +441 relative to the transcription start site. … In an electrophoretic mobility shift assay using the nuclear extracts from HepG2 cells and the synthetic oligonucleotide containing the Sp1 site, specific DNA-protein complexes were identified. …

Journal of Nutritional Science and Vitaminology 51(4), 274-277, 2005-08

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19

Analysis of Human UDP-Glucose Dehydrogenase Gene Promoter : Identification of an Sp1 Binding Site Crucial for the Expression of the Large Transcript

VATSYAYAN Jaya , PENG Hwei-Ling , CHANG Hwan-You

The journal of biochemistry 137(6), 703-709, 2005-06-01

医中誌参考文献18件被引用文献1件
20

Analysis of the Promoter Region of the Xenopus General Type TFIIS (TCEA1) Gene

Kugawa Fumihiko , Aoki Masatada

… TFIIS is a general transcription elongation factor that interacts with Elongin (SIII), a product of the tumor suppressor gene for the human hereditary disorder von Hippel-Lindau (VHL) disease. … Except for the proximal promoter region close to the transcription start sites, no positively or negatively regulating element was found for TFIIS gene expression within the 1600-bp upstream region of the XGTFIIS gene. …

Journal of health science 50(5), 551-555, 2004-10-01

CiNii PDF - オープンアクセス J-STAGE CrossRef 参考文献25件

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