Wada Akihiro
,
Hasegawa Makoto
,
Wong Pooi-Fong
,
Shirai Emi
,
Shirai Nobuaki
,
Tan Li-Jing
,
Llanes Rafael
,
Hojo Hironobu
,
Yamasaki Eiki
,
Ichinose Akitoyo
,
Ichinose Yoshio
,
Senba Masachika
… Here, we show that treatment with ganglioside mixture at a concentration of 100 microg/mL resulted in significant inhibition of the vacuole formation activity of Helicobacter pylori vacuolating cytotoxin (VacA) in gastric epithelial cancer AZ-521 cells. … All gangliosides (GM1, GM2, GM3, GD1a, GD1b, GD3 and GT1b) examined showed good neutralizing capacity against VacA. … A pull-down assay was performed using lyso-GM1 coupled to Sepharose as the tagged polysaccharide polymer to capture VacA from H. …
Glycobiology 20(6), 668-678, 2010-06-00
IR