Search Results: 1-20 of 47

1

Goshuyuto, a Traditional Japanese Medicine, and Aqueous Extracts of Evodiae Fructus Constrict Isolated Rat Aorta via Adrenergic and/or Serotonergic Receptors(Pharmacology)

HIBINO Tomoko , YUZURIHARA Mitsutoshi , KANNO Hitomi , KASE Yoshio , TAKEDA Atsushi

… In addition, aqueous extracts of Evodiae Fructus, one of the constituent medicinal herbs of goshuyuto, caused constriction of aorta strips strongly, but aqueous extracts of Zizyphi Fructus, Ginseng Radix, and Zingiberis Rhizoma, the other constituents of goshuyuto, did not have much effect on the vascular response of rat aorta strips. …

Biological & pharmaceutical bulletin 32(2), 237-241, 20090201

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2

Goshuyuto, a Traditional Japanese Medicine for Migraine, Inhibits Platelet Aggregation in Guinea-Pig Whole Blood

HIBINO Tomoko , YUZURIHARA Mitsutoshi , TERAWAKI Kiyoshi , KANNO Hitomi , KASE Yoshio , TAKEDA Atsushi

… Of them, aqueous extracts of Evodiae Fructus and Zingiberis Rhizoma inhibited platelet aggregation, but aqueous extracts of Zizyphi Fructus and Ginseng Radix did not. … Two components of Zingiberis Rhizoma, 6-shogaol and 6-gingerol, also inhibited platelet aggregation. …

Journal of Pharmacological Sciences 108(1), 89-94, 20080920

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3

Blockade of the Dioxin Pathway by Herbal Medicine Formula Bupleuri Minor : Identification of Active Entities for Suppression of AhR Activation(Molecular and Cell Biology)

KASAI Ayumi , HIRAMATSU Nobuhiko , HAYAKAWA Kunihiro , YAO Jian , KITAMURA Masanori

… Some constituents including Bupleuri Radix and Zingiberis Rhizoma rather activated AhR. …

Biological & pharmaceutical bulletin 31(5), 838-846, 20080501

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4

The Role of Roasted Glycyrrhiza Root in the Main Prescriptions for Shoinbyo(shao yin bing) [in Japanese]

FUKUTA Yoshihiro

Japanese Journal of Oriental Medicine 57(6), 769-779, 20061120

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5

Pharmacokinetics of (-)Epicatechin 3-O-Gallate, Glycyrrhetic Acid and Rhein in Healthy Male Volunteers after Multiple Dose Administration of TJ-8117 (Unpito), a Japanese Traditional Medicine for Renal Failure

TAKIZAWA Yukiho , MIZUHARA Yasuharu , MORITA Toshimi , KASE Yoshio , TAKEDA Shuichi , ABURADA Masaki , MIYAMOTO Ken'ichi

… Aims: Unpito, an herbal medicine extracted from a mixture of five crude medicines (Rhei Rhizoma, Glycyrrhizae Radix, Ginseng Radix, Zingiberis Rhizoma and Aconiti Tuber), has been developed as a drug for chronic renal failure. …

臨床薬理 = JAPANESE JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 37(1), 33-40, 20060131

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6

Pharmacokinetics of (-)Epicatechin 3-O-Gallate, Glycyrrhetic Acid and Rhein in Healthy Male Volunteers after a Single Dose Administration of TJ-8117 (Unpito), a Japanese Traditional Medicine for Renal Failure

TAKIZAWA Yukiho , MIZUHARA Yasuharu , MORITA Toshimi , KASE Yoshio , TAKEDA Shuichi , ABURADA Masaki , MIYAMOTO Ken'ichi

… Aims: Unpito, an herbal medicine extracted from a mixture of five crude medicines (Rhei Rhizoma, Glycyrrhizae Radix, Ginseng Radix, Zingiberis Rhizoma and Aconiti Tuber), has been developed as a drug for chronic renal failure. …

J Clin Pharmacol Ther 37(1), 21-32, 20060131

Ichushi IR References (23) Cited by (1)
7

The Effect of Nichin-to on the Plasma Gut-Regulatory Peptide Level in Healthy Human Subjects

Katagiri Fumihiko , Inoue Shin , Sato Yuhki , Itoh Hiroki , Takeyama Masaharu

… For example, Nichin-to is a combination of five herbs : Pinelliae Tuber, Zingiberis Rhizoma, Poria, Glycyrrhizae Radix and Aurantii Nobilis Pericarpium. …

Journal of health science 51(2), 172-177, 20050401

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8

Effects of 19 Herbal Extracts on the Sensitivity to Paclitaxel or 5-Fluorouracil in HeLa Cells(Biopharmacy)

TAKARA Kohji , HORIBE Sayo , OBATA Yukihisa , YOSHIKAWA Eri , OHNISHI Noriaki , YOKOYAMA Teruyoshi

… Glycyrrhizae Radix, Rhei Rhizoma, Scutellariae Radix, Poria, Zizyphi Fructus, Zingiberis Rhizoma (dry), Coptidis Rhizoma, Ephedrae Herba and Asiasari Radix significantly enhanced the sensitivity to a MDR1 substrate paclitaxel, whereas none of the herbal extracts used had any effect on the sensitivity to 5-fluorouracil, which is not a substrate for MDR1. …

Biological & pharmaceutical bulletin 28(1), 138-142, 20050101

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9

Comparison of the Effects of Sho-hange-ka-bukuryo-to and Nichin-to on Human Plasma Adrenocorticotropic Hormone and Cortisol Levels with Continual Stress Exposure(Pharmacology)

KATAGIRI Fumihiko , INOUE Shin , SATO Yuhki , ITOH Hiroki , TAKEYAMA Masaharu

… To determine the pharmacological effects of Sho-hange-ka-bukuryo-to, Nichin-to, and the two herbs (Pinelliae Tuber and Zingiberis Rhizoma, both of which are included in Sho-hange-ka-bukuryo-to and Nichin-to), we examined the effects of these medicines on the plasma levels of adrencorticotropic hormone (ACTH) and cortisol under stress conditions by repetitive blood sampling. …

Biological & pharmaceutical bulletin 27(10), 1679-1682, 20041001

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10

Effect of Sho-hange-ka-bukuryo-to on Gastrointestinal Peptide Concentrations in the Plasma of Healthy Human Subjects(Pharmacology)

KATAGIRI Fumihiko , ITOH Hiroki , TAKEYAMA Masaharu

… For example, Sho-hange-ka-bukuryo-to is prepared from three herbs : Pinelliae Tuber, Zingiberis Rhizoma and Hoelen. …

Biological & pharmaceutical bulletin 27(10), 1674-1678, 20041001

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11

Comparison of the Effects of Hange-shashin-to and Rikkunshi-to on Human Plasma Calcitonin Gene-Related Peptide and Substance P Levels(Pharmacology)

NAITO Takafumi , ITOH Hiroki , TAKEYAMA Masaharu

… Extract of a 2.5 g Zingiberis rhizoma significantly caused increases in CGRP-IS at 40 min and in substance P-IS at 60 min. These results, in comparison with Kampo medicines, might indicate that the pharmacological actions of Hange-shashin-to closely are related to changes in CGRP-IS and substance P-IS levels, while Zingiberis rhizoma partially might participate in those effects of Hange-shashin-to. …

Biological & pharmaceutical bulletin 26(8), 1104-1107, 20030801

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12

Pharmacokinetics of Rhein from Onpi-to, an Oriental Herbal Medicine, in Rats

TAKIZAWA Yukiho , MOROTA Takashi , TAKEDA Shuichi , ABURADA Masaki

… Onpi-to, an herbal medicine composed of five crude drugs (Rhei Rhizoma, Glycyrrhizae Radix, Ginseng Radix, Zingiberis Rhizoma and Aconiti Tuber), was administered orally to rats. …

Biological & pharmaceutical bulletin 26(5), 613-617, 20030501

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13

Pharmacokinetics of (-)-Epicatechin-3-0-gallate, an Active Component of Onpi-to, in Rats

TAKIZAWA Yukiho , MOROTA Takashi , TAKEDA Shuichi , ABURADA Masaki

… (-)-Epicatechin-3-0-gallate (ECG), a component of Rhei Rhizoma, is one of the active components of Onpito, a herbal medicine composed of five crude drugs (Rhei Rhizome, Glycyrrhizae Radix, Ginseng Radix, Zingiberis Rhizoma and Aconiti Tuber), which has been used in patients with chronic renal failure. …

Biological & pharmaceutical bulletin 26(5), 608-612, 20030501

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14

Effects of olfactory and gustatory stimulation of Zingiberis rhizoma on the efferent nerve activity of the gastric branch of the vagus nerve and adrenal branch of the sympathetic nerve [in Japanese]

Niijma Akira , Hashimoto Kazunori , Sakakibara Iwao , Amagaya Sakae , Aburada Masaki

… The effects of olfactory stimulation and gustatory stimulation of singer (Zincebris rhizoma) solution on the efferent activity of the gastric branch of the vagus nerve and the adrenal branch of the sympathetic nerve were observed in the anesthetized rat. …

The Japanese journal of taste and smell research 10(1), 97-102, 20030400

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15

Pharmacological Evaluation of Shokyo and Kankyo (1)

HASHIMOTO Kazunori , KASE Yoshio , MURATA Pin , KIDO Toshitaka , NAKAI Yoichiro , SAKAKIBARA Iwao , HIGUCHI Masami , SASAKI Hiroshi , OKADA Minoru

… Zingiberis Rhizoma (Shokyo, 生姜) showed significant ameliorative effect on the BaCl2-induced delay of gastric emptying in rat. …

Biological & pharmaceutical bulletin 25(9), 1183-1187, 20020901

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16

Herbal Medicine and False-Positive Results on Lymphocyte Transformation Test

MANTANI Naoki , SAKAI Shinya , KOGURE Toshiaki , GOTO Hirozo , SHIBAHARA Naotoshi , KITA Toshiaki , SHIMADA Yutaka , TERASAWA Katsutoshi

… in the suspect Kampo medicines, resulting in positive LTT for 17 herbs: Evodiae Fructus (Goshuyu), Zizyphi Fructus (Taiso), Ginseng Radix (Ninjin), Zingiberis Rhizoma (Shokyo), Hoelen (Bukuryo), Aconiti Tuber (Bushi), Angelicae Radix (Toki), Cnidii Rhizoma (Senkyu), Rehmanniae Radix (Jio), Ephedrae Herba (Mao), Anemarrhenae Rhizoma (Chimo), Cinnamomi Cortex (Keihi), Bupleuri Radix (Saiko), Artemisiae Capillari Spica (Inchinko), Persicae Semen (Tonin), Moutan Cortex (Botanpi) …

Journal of the Pharmaceutical Society of Japan 122(6), 399-402, 20020601

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17

Trends in the prescriptions of Kampo medicines over a six-year period

AKASE Tomohide , HAMADA Yukihiro , HIGASHIYAMA Daisuke , AKASE Tomoko , TASHIRO Shin-ichi , SAGAWA Ken-ichi , SHIMADA Shigehiko

医療用漢方エキス製剤(以下,漢方エキス製剤)の処方動向および問題点の抽出を目的に,首都圏の特定機能病院において使用実態調葦を行った。1994年から1999年までの6年間に発行された漢方エキス製剤を含む79,132枚の処方箋を解析した。調査対象施設では63品目の漢方エキス製剤が採用されていた。年齢別処方動向は,30代から60代の年齢層の患者に多く処方される傾向があり,診療科別では婦人科,内科,皮膚科 …

Journal of traditional medicines 19(2), 58-75, 20020420

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18

Cell Differentiation Inducers and Antiandrogenic Active Compounds from Zingiberis Rhizoma

KUROYANAGI Masanori , UMEHARA Kaoru , HAYASHI Tatsuo , HIRAYAMA Yutaka

Natural Medicines 56(2), 47-50, 20020420

Ichushi References (17)
19

The Effects of a Traditional Medicine, Fang-ji-huang-qi-tang (Boi-ogi-to), on Urinary Sugar and Sugar Alcohols in Streptozotocin-induced Diabetic Mice

Liu Yuan Ying , Tsutsumi Taiki , Zhang Chunhua , Matsumoto Isamu

… Boi-ogi-to (Fang-ji-huang-qi-tang, FJHQ) is a Kampo Medicine which has been clinically used in the treatment of arthritis and edema, and includes Astragali Radix, Atractylodes Lanceae Rhizoma, Glycyrrhizae Radix, Zingiberis Rhizoma and Zizyphi Fructus combined with Sinomeni Caulis et Rhizoma (SCR) in Japan, hut with Stephania Radix (SR) in China as a substitute for SCR. …

Journal of health science 48(2), 168-172, 20020401

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20

Combined effects of Stephania Radix and Astragali Radix in antihyperglycemic action of Boi-ogi-to (Fang-ji-huang-qi-tang) in streptozotocin-induced diabetic mice

LIU Yuan Ying , KOBAYASHI Shinjiro , TSUTSUMI Taiki , KONTANI Hitoshi

粉防已を用いた防已黄耆湯(48-160mg/kg/day)は,防已を用いた防已黄耆湯と比較して,ストレプトゾトシン(STZ)-誘発糖尿病ddY マウスの高血糖値を有意に下降させた。防已黄者湯の血糖下降作用は,腹腔内投与と経口投与のいずれにも見られ,血中へのインスリン遊離促進作用と平行した。各構成生薬の単味およぴ混合物,方剤からの一味抜き方剤の血糖下降作用を防已黄耆湯の作用と比較した。防己黄耆湯から …

Journal of traditional medicines 17(6), 253-260, 20001215

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