検索結果 15300件中 1-20 を表示

  • Effect of temperature on queen oviposition and seasonal colony development in Lasius japonicus (Hymenoptera: Formicidae)

    Nakamura Keiji , Fujiyama Midori , Ohta Kouhei

    Applied entomology and zoology 52(1), 107-112, 2017-02

  • Biological dose representation for carbon-ion radiotherapy of unconventional fractionation

    Kanematsu Nobuyuki , Inaniwa Taku

    … In carbon-ion radiotherapy, single-beam delivery each day in alternate directions has been common practice for effcient operation, taking advantage of the Bragg peak and the relative biological effectiveness (RBE) for uniform dose conformation to a tumor. … however, this is of limited relevance to the biological effect. …

    Physics in Medicine and Biology 62(3), 1062-1075, 2017-01

    機関リポジトリ DOI

  • Heartworm extract induces relaxation of isolated rat thoracic aorta

    KITOH Katsuya , NAKAMURA Hiroaki , KITAGAWA Hitoshi , UNNO Toshihiro , KOMORI Seiichi , CHIOU Shin-Pin , TAKASHIMA Yasuhiro

    … This effect was inhibited by treatment with <i>N<sup>G</sup></i>-nitro-L-arginine methyl ester hydrochloride (L-NAME) and could be reversed by additional treatment with L-arginine. …

    The Journal of Veterinary Medical Science, 2017


  • Impact of Phenyl Groups on Oxygen-bridged V-shaped Organic Semiconductors

    Mitsui Chikahiko , Kubo Wataru , Tanaka Yuji , Yamagishi Masakazu , Annaka Tatsuro , Dosei Hiroaki , Yano Masafumi , Nakamura Ken-ichi , Iwasawa Daichi , Hasegawa Miki , Takehara Tsunayoshi , Suzuki Takeyuki , Sato Hiroyasu , Yamano Akihito , Takeya Jun , Okamoto Toshihiro

    <p>We have developed two novel, isomeric compounds of phenyl-substituted dinaphtho[2,3-<i>b</i>:2′,3′-<i>d</i>]furan (<b>Ph-DNF-VW</b> and <b>Ph-DNF-VV& …

    Chemistry Letters 46(3), 338-341, 2017


  • 循環扇がパッドアンドファン冷房温室内の気流分布に与える影響

    東海林 孝幸 , 住 暁浩 , 下村 徳仁 , 熊崎 忠 , 鈴木 邦典 , 三枝 正彦

    パッドアンドファン冷房温室において栽培室に設置されている循環扇と群落内気流性状の関係を数値流体力学モデル(CFD)により調べた.シミュレーション結果より循環扇の稼働は群落内の平均気流速を増加させる一方で気流ムラも発生させること,循環扇の吹き出しをパッドから換気扇の方向にすると群落内がほぼ無風になること,循環扇を配置する際,吹き出し流の到達範囲に他の循環扇の吸い込み口が含まれるように配置することで気 …

    植物環境工学 29(1), 17-25, 2017


  • 3D Printing Factors Important for the Fabrication of Polyvinylalcohol Filament-Based Tablets

    Tagami Tatsuaki , Fukushige Kaori , Ogawa Emi , Hayashi Naomi , Ozeki Tetsuya

    … In current study, polyvinylalcohol (PVA)-based tablets were prepared using a fused-deposition-modeling-type 3D printer and the effect of 3D printing conditions on tablet production was investigated. …

    Biological & Pharmaceutical Bulletin 40(3), 357-364, 2017


  • Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including <i>O</i>-GlcNAcylation

    Takeuchi Tomoharu , Sugimoto Aya , Imazato Nao , Tamura Mayumi , Nakatani Sachie , Kobata Kenji , Arata Yoichiro

    … In this study, we investigated the effect of glucosamine (GlcN), a nutrient used to prevent joint pain and bone loss, on the osteoclastogenesis of murine macrophage-like RAW264 cells. … To clarify the mechanism by which GlcN suppresses osteoclastogenesis, we further investigated the effect of GlcN on <i>O</i>-GlcNAcylation by Western blotting and on other types of glycosylation by lectin blotting. …

    Biological & Pharmaceutical Bulletin 40(3), 352-356, 2017


  • Anti-hyperglycemic Effect of Long-Term Bis(hinokitiolato)zinc Complex ([Zn(hkt)₂]) Ingestion on Insulin Resistance and Pancreatic Islet Cells Protection in Type 2 Diabetic KK-A[y] Mice

    Naito Yuki , Yoshikawa Yutaka , Shintani Michiko , Kamoshida Shingo , Kajiwara Naemi , Yasui Hiroyuki

    … This accumulation of Zn in pancreas suggested that [Zn(hkt)<sub>2</sub>] mainly effects on the peripheral tissue, and [Zn(hkt)<sub>2</sub>] has the less effect on the pancreas directly. … Thus, we concluded that [Zn(hkt)<sub>2</sub>] exerted the main effect on peripheral organs by ameliorating insulin resistance.</p> …

    Biological & Pharmaceutical Bulletin 40(3), 318-326, 2017


  • Protection of Cultured Cortical Neurons by Luteolin against Oxidative Damage through Inhibition of Apoptosis and Induction of Heme Oxygenase-1

    Kim Sunyoung , Chin Young-Won , Cho Jungsook

    … <p>Luteolin, one of the most common flavonoids present in many types of natural products, possesses diverse biological properties including anti-oxidant activity. … In this study, we investigated neuroprotective effect of luteolin and its underlying signaling pathways using primary cultured rat cortical cells. … These results indicate that luteolin exhibits neuroprotective effect through the inhibition of ROS and apoptotic cell death. …

    Biological & Pharmaceutical Bulletin 40(3), 256-265, 2017


  • Cinepazide Maleate Improves Cognitive Function and Protects Hippocampal Neurons in Diabetic Rats with Chronic Cerebral Hypoperfusion

    Li Yumei , Zhang Ting , Zhang Xiaojie , Zou Wenying , Gong Xian , Fu Jianliang

    … <p>To determine the combined effect of type 2 diabetes (T2D) and chronic cerebral hypoperfusion (CCH) on learning and spatial memory, we developed a rat model of CCH by permanent occlusion of bilateral common carotid arteries (2-vessel occlusion (2VO)) in high-fat diet (HFD)-fed rats injected with low-dose streptozotocin (STZ). … Furthermore, we examined the effect of cinepazide maleate (CM) on cognitive deficits and brain damage in this rat model. …

    Biological & Pharmaceutical Bulletin 40(3), 249-255, 2017


  • 過酸化水素の植物プランクトン,ワカメ配偶体,シオダマリミジンコ,タテジマフジツボ幼生に対する影響

    小平 雅之 , 松本 智彦 , 山田 雄一郎 , 難波 信由 , 加戸 隆介

    … Therefore, we studied the biological effect of hydrogen peroxide on five phytoplanktons (<i>Heterocapsa triquetra</i>, <i>Rhodomonas salina</i>, <i>Tetraselmis</i> … Test results indicated that the lowest no observed effect concentrations (NOEC) of hydrogen peroxide and residual chlorine were estimated to be 1.05 mg/L and less than 0.1 mg/L for all the organisms used in this study, respectively. …

    Sessile Organisms 34(1), 1-12, 2017


  • SAR analysis in the eye of human whole-body model for plane-microwave exposure

    Kuwano Shuzo , Kobayashi Makoto , Michiyama Tetsuyuki

    <p>We numerically analyze the specific absorption rate (SAR) in the eye of anatomically based human whole-body model exposed to E-polarized plane wave in the frequency range from 0.6 to 4 GHz. A …

    IEICE Communications Express, 2017


  • Protective effects of tyrosol against LPS-induced acute lung injury via inhibiting NF-κB and AP-1 activation and activating the HO-1/Nrf2 Pathways

    Wang Wen-chen , Xia Yan-min , Yang Bo , Su Xiang-ni , Chen Jia-kuan , Li Wei , Jiang Tao

    … The present study aimed to investigate the effect and mechanism of Tyr on lipopolysaccharide (LPS)-induced acute lung injury (ALI). …

    Biological & Pharmaceutical Bulletin, 2017


  • Evaluation of the Clinical Benefit of a G-CSF Biosimilar

    KAMADA Izumi , SAITOU Yasumasa , SIMIZU Tadahiro , ASAKAWA Kyouko , MASUOKA Kazuhiro , KOBAYASHI Tetsu , ISHII-WATABE Akiko , TOYOSHIMA Satoshi

    <p>バイオ医薬品は, 一般的に有用性は高いが, 高薬価のため医療費高額の一因となっている. そのため医療費抑制となるバイオ後続品 (Biosimilar: BS) 使用への期待が高まっているが, 国内でのBS使用は低分子化学医薬品である後発医薬品に比較し進んでいない. その主たる原因は, 医師, 薬剤師のBSと先行バイオ医薬品との同等性に関する認識が必ずしも十分でないためと考えられた …

    レギュラトリーサイエンス学会誌 7(1), 3-15, 2017


  • Crown-cooling Treatment Induces Earlier Flower Bud Differentiation of Strawberry under High Air Temperatures

    HIDAKA Kota , DAN Kazuhiro , IMAMURA Hitoshi , TAKAYAMA Tomohiko

    … With the aim of ensuring future stable production of strawberry under high autumn air temperatures, we examined the effect of a crown-cooling treatment on flower bud differentiation, flowering characteristics and fruit yield in a June-bearing strawberry (<I>Fragaria×ananassa</I> …

    Environment Control in Biology 55(1), 21-27, 2017


  • Cell death affected by dental alloys: Modes and mechanisms

    PAN Yu , JIANG Lei , LIN Honglei , CHENG Hui

    … In order to make it clear, the cytotoxic effect of four dental alloys on L929 cells was evaluated by flow cytometry (FCM) and Real-time quantitative PCR assay (Real-time qPCR) to identify the cell death mode and its biological mechanism. …

    Dental Materials Journal 36(1), 82-87, 2017


  • Intrathecal Dexmedetomidine Alleviates Shivering during Cesarean Delivery under Spinal Anesthesia

    He Liang , Xu Jun-Mei , Liu Su-Mei , Chen Zhi-Jun , Li Xin , Zhu Rong

    … In this prospective, randomized, double-blind, placebo-controlled study, we sought to evaluate the effect of intrathecal dexmedetomidine, administered as an adjunct to hyperbaric bupivacaine for Cesarean delivery, on the incidence and severity of shivering associated with spinal anesthesia. …

    Biological & Pharmaceutical Bulletin 40(2), 169-173, 2017


  • Inhibition of Neutrophil Adhesion and Antimicrobial Activity by Diluted Hydrosol Prepared from <i>Rosa damascena</i>

    Maruyama Naho , Tansho-Nagakawa Shigeru , Miyazaki Chizuru , Shimomura Kazuyuki , Ono Yasuo , Abe Shigeru

    … These findings suggest that rose water has a potential effect to inhibit skin inflammation caused by microbes.</p> …

    Biological & Pharmaceutical Bulletin 40(2), 161-168, 2017


  • Preparation and Evaluation of PEGylated Poly-L-ornithine Complex as a Novel Absorption Enhancer

    Kamiya Yusuke , Yamaki Tsutomu , Uchida Masaki , Hatanaka Tomomi , Kimura Mitsutoshi , Ogihara Masahiko , Morimoto Yasunori , Natsume Hideshi

    … PLO showed cytotoxicity at high concentrations, whereas PEG-PLO did not decrease cell viability, even above the concentration giving a sufficient enhancement effect. …

    Biological & Pharmaceutical Bulletin 40(2), 205-211, 2017


  • Modifying Cationic Liposomes with Cholesteryl-PEG Prevents Their Aggregation in Human Urine and Enhances Cellular Uptake by Bladder Cancer Cells

    Nakamura Takashi , Noma Yosuke , Sakurai Yu , Harashima Hideyoshi

    … We report on an examination of the effect of modifying liposomes with polyethylene glycol (PEG) lipids to prevent Cat-LPs from aggregating in human urine. …

    Biological & Pharmaceutical Bulletin 40(2), 234-237, 2017