検索結果:　 250件中 1-20 を表示

1

Differential roles of calcitonin family peptides in the dendrite formation and spinogenesis of the cerebral cortex in vitro

Harigai Yuichi , Natsume Masaki , Li Fei , Ohtani Akiko , Senzaki Kouji , Shiga Takashi , 先崎浩次 , 志賀隆

… We examined roles of calcitonin family peptides in the initial stages of dendrite formation and the maturation of dendritic spines in the rat cerebral cortex in vitro. … Embryonic day 18 cortical neurons were dissociated and cultured for 2–3 days in the presence of calcitonin gene-related peptide (CGRP), calcitonin, amylin or adrenomedullin. …

Neuropeptides 45(4), 263-272, 2011-08

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2

Effect of neuropeptides on human dental pulp cells; mRNA expression of proinflammatory cytokines

Shida Muneyasu , Baba Tadahiko , Taguchi Yoichiro , Okamura Tomoharu , Tanaka Akio , Ueda Masatoshi , Hayashi Hiroyuki

… Substance P (SP) and calcitonin gene-related peptide (CGRP) were used as neuropeptides. … At six hours after stimulation, the IL-8 mRNA expression of the SP 10^<-5>M, SP 10^<-4>M, and CGRP 10^<-6>M groups were significantly different from that of the negative control (p<0.05). …

Journal of Osaka Dental University 45(1), 129-133, 2011-04

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3

Neuropeptide Effects in the Trigeminal System: Pathophysiology and Clinical Relevance in Migraine

Messlinger Karl , Fischer Michael J. M. , Lennerz Jochen K.

… The neuropeptides substance P, calcitonin gene-related peptide (CGRP) and vasoactive intestinal polypeptide (VIP) have been considered as important mediators in migraine and other primary headaches. …

The Keio Journal of Medicine 60(3), 82-89, 2011

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4

Comparison of the Effects of Pantethine and Fursultiamine on Plasma Gastrointestinal Peptide Levels in Healthy Volunteers

Suzuki Yosuke , Itoh Hiroki , Abe Tomohide , Nishimura Fumihiro , Sato Yuhki , Takeyama Masaharu

… In recent years, the actions of drugs used to treat gastrointestinal diseases have been elucidated pharmacologically from the viewpoints of gastrointestinal peptide levels. … We examined the effects of pantethine and fursultiamine on plasma levels of calcitonin gene-related peptide (CGRP)-, vasoactive intestinal polypeptide (VIP)-, motilin- and substance P (SP)-like immunoreactive substances (IS) in healthy subjects. …

Biological & Pharmaceutical Bulletin 34(10), 1640-1643, 2011

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5

The Effects of Risedronate and Exercise on Osteoporotic Lumbar Rat Vertebrae and Their Sensory Innervation

ORITA Sumihisa , OHTORI Seiji , KOSHI Takana , YAMASHITA Masaomi , YAMAUCHI Kazuyo , INOUE Gen , SUZUKI Munetaka , EGUCHI Yawara , KAMODA Hiroto , ISHIKAWA Tetsuhiro , MIYAGI Masayuki , OCHIAI Nobuyasu , KISHIDA Shunji , TAKASO Masashi , AOKI Yasuchika , TOYONE Tomoaki , TAKAHASHI Kazuhisa

Spine 35(22), 1974-1982, 2010-10-15

参考文献33件
6

【消化器疾患と漢方】消化管血流と漢方

河野　透

… 腸管血流増加作用を実験的に検証した結果、大建中湯の主要生薬である山椒の主成分hydroxy-α-sanshool、乾姜の主成分6-shogaolが腸管粘膜に作用し神経終末から神経ペプチドcalcitonin gene-related peptide、腸管上皮細胞からアドレノメデュリンという2つの強力な微小血管拡張作用を有するカルシトニンファミリーペプチドを介して作用を発現し、さらに受容体関連因子を …

G.I.Research 18(4), 268-275, 2010-8

機関リポジトリ医中誌
7

Direct Evidence for Sensory Innervation of the Dorsal Portion of the Co5/6 Coccygeal Intervertebral Disc in Rats

ORITA Sumihisa , OHTORI Seiji , TANIGUCHI Aya , YAMASHITA Masaomi , YAMAUCHI Kazuyo , INOUE Gen , SUZUKI Munetaka , EGUCHI Yawara , OCHIAI Nobuyasu , KISHIDA Shunji , TAKASO Masashi , AOKI Yasuchika , TAKAHASHI Kazuhisa , KAWAKAMI Mamoru

Spine 35(14), 1346-1352, 2010-06-15

参考文献21件
8

Effects of Topical Application of α-D-Glucosylglycerol on Dermal Levels of Insulin-Like Growth Factor-I in Mice and on Facial Skin Elasticity in Humans

HARADA Naoaki , ZHAO Juan , KURIHARA Hiroki , NAKAGATA Naomi , OKAJIMA Kenji

… Sensory neurons release calcitonin-gene related peptide (CGRP) on stimulation. … GG increased CGRP release and cAMP levels in dorsal root ganglion (DRG) neurons isolated from wild-type mice. … Pretreatment with capsazepine, an inhibitor of vanilloid receptor-1 activation, and with KT5720, an inhibitor of protein kinase A, reversed GG-induced increases in CGRP release from DRG neurons. …

Bioscience, biotechnology, and biochemistry 74(4), 759-765, 2010-04-23

J-STAGE 医中誌 CrossRef 参考文献37件
9

カルシトニン遺伝子関連ペプチド(CGRP) (広範囲血液・尿化学検査免疫学的検査(第7版・4)その数値をどう読むか) -- (内分泌学的検査甲状腺・副甲状腺関係)

池田佳史 , 高見博

日本臨床 68(-) (982), 328-330, 2010-07

医中誌
10

血管周囲神経リモデリングにおけるアンジオテンシン受容体の役割

芳原成美 , 合田光寛 , 橋川直也 , 金鑫 , 座間味義人 , 高取真吾 , 川﨑博己

… The aim of this study was to investigate age-related changes in the density of calcitonin gene-related peptide (CGRP)-containing nerve fibers in spontaneously hypertensive rats (SHR) and the effects of long-term inhibition of the renin-angiotensin system on these changes. …

YAKUGAKU ZASSHI 130(11), 1421-1425, 2010

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11

血管周囲神経の再分布とアンジオテンシン受容体の役割

芳原成美 , 合田光寛 , 吉田菜三夏 , 橋川直也 , 川﨑博己

… Phenol treatment markedly reduced densities of both calcitonin gene-related peptide (CGRP)-like immunoreactivity (LI)- and neuropeptide Y (NPY)-LI-containing fibers. … Coadministration of Ang II and losartan (AT1R antagonist) significantly increased the density of CGRP-LI-fibers but not NPY-LI-fibers compared with saline control. …

YAKUGAKU ZASSHI 130(9), 1189-1195, 2010

J-STAGE 医中誌 CrossRef
12

Propolis 長期投与による Otsuka Long-Evans Tokushima Fatty (OLETF) ラットのインスリン抵抗性改善作用

座間味義人 , 藤原弘喜 , 細田美穂 , 日野隼人 , 平井和浩 , 岡本和明 , 金鑫 , 高取真吾 , 高木(土井) 志真 , 川﨑博己

… In isolated and perfused mesenteric vascular beds of OLETF rats, propolis treatment resulted in significant reduction of sympathetic nerve-mediated vasoconstrictor response to periarterial nerve stimulation (PNS) and tended to increase calcitonin gene-related peptide (CGRP) nerve-mediated vasodilator response to PNS compared with in vehicle-treated OLETF rats. …

YAKUGAKU ZASSHI 130(6), 833-840, 2010

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13

Effects of bakumondoto on neuropeptide levels in human saliva and plasma

佐藤雄己 , ITOH Hiroki , TAKEYAMA Masaharu

… 唾液腺にはsubstance P,calcitonin gene-related peptide(CGRP),and vasoactive intestinal polypeptide(VIP)などの神経ペプチドが局在している。 …

和漢医薬学雑誌 26(3), 122-130, 2009-08-31

CiNii PDF - オープンアクセス医中誌参考文献30件
14

Decreased Expression of Transient Receptor Potential Vanilloid 1 Impairs the Postischemic Recovery of Diabetic Mouse Hearts

WEI Zhonghai , WANG Lihong , HAN Jie , SONG Junxian , YAO Lei , SHAO Lei , SUN Zhihui , ZHENG Liangrong

… The expression of both TRPV1 and calcitonin gene-related peptide (CGRP) in diabetes mellitus (DM) hearts was significantly lower, as determined by Western blot and radioimmunoassay, respectively. … Pretreatment with CGRP in both non-DM and DM hearts protected hearts against ischemic injury. …

Circulation journal : official journal of the Japanese Circulation Society 73(6), 1127-1132, 2009-05-20

J-STAGE 医中誌 CrossRef 参考文献33件被引用文献2件
15

The effect and mechanism of action of capsaicin on gastric acid output

IMATAKE Kazuhiro , MATSUI Teruaki , MORIYAMA Mitsuhiko

Journal of gastroenterology 44(5), 396-404, 2009-05-01

参考文献42件
16

Calcitonin Receptor-Stimulating Peptide and Calcitonin/Calcitonin Gene-Related Peptide : Their Evolutionary and Functional Relation in Mammals

MINAMINO Naoto , OSAKI Tsukasa , YASUE Hiroshi , KATAFUCHI Takeshi

Peptide science : proceedings of the ... Japanese Peptide Symposium 2008, 99-102, 2009-03-01

参考文献3件
17

血管作動性物質--生合成,分泌,生理作用 PTH/PTH関連ペプチド,カルシトニン遺伝子関連ペプチド (高血圧(第4版)--日本における最新の研究動向(上)) -- (循環生理活性物質の最新知見)

田原英樹 , 西沢良記

日本臨床 67(-) (964), 278-282, 2009-10

医中誌
18

DORSAL ROOT REGENERATION INTO TRANSPLANTS OF DORSAL OR VENTRAL HALF OF EMBRYONIC SPINAL CORD

OHTA Tohru , ITOH Yasunobu , TESSLER Alan , MIZOI Kazuo

… We used calcitonin gene-related peptide (CGRP) immunohistochemistry to label to the subpopulations of regenerated adult dorsal root axons, quantitative analysis to compare the extent of dorsal root regeneration, and also compare neuronal composition within both transplants. … Three months later sagittal sections were prepared for CGRP immunohistochemistry and Nissl-Myelin stain. …

秋田医学 36(2), 61-70, 2009

機関リポジトリ医中誌
19

Neurotrophic Effect of Hepatic Growth Factor (HGF) on Reinnervation of Perivascular Calcitonin Gene-Related Peptide (CGRP)-Containing Nerves Following Phenol-Induced Nerve Injury in the Rat Mesenteric Artery

HOBARA Narumi , YOSHIDA Namika , GODA Mitsuhiro , YOKOMIZO Ayako , KITAMURA Yoshihisa , SENDOU Toshiaki , KAWASAKI Hiromu

Journal of pharmacological sciences 108(4), 495-504, 2008-12-20

医中誌参考文献24件
20

Possible Role of Spleen Derived Factors, Vanilloid Receptors and Calcitonin Gene-related Peptide in Diabetes Induced Hyperalgesia in Mice

KHAN Nadeem , SINGH Nirmal , JAGGI Amteshwar Singh

… The present study was designed to investigate a possible role of vanilloid receptors, CGRP and spleen in the induction of diabetes induced hyperalgesia in mice. … Administration of ruthenium red (1mg/kg^<-1>, i.p.), vanilloid receptor antagonist, and sumatriptan (50mg/kg^<-1>, i.p.), a CGRP release inhibitor, attenuated diabetes and SHS induced decrease in nociceptive threshold and increase in serum nitrite oxide levels. …

藥學雜誌 128(11), 1699-1705, 2008-11-01

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