CiNii Search - clinical trial

1

Three-year clinical evaluation of a flowable and a hybrid resin composite in non-carious cervical lesions.

Kubo Shisei , Yokota Hiroaki , Yokota Haruka , Hayashi Yoshihiko

… OBJECTIVES: This randomized controlled clinical trial evaluated the 3-year clinical performance of a hybrid (Clearfil AP-X; … There were no significant differences in the clinical performances between AP and FX for each variable. … CONCLUSIONS: Under the protocol used in this study, both types of resin composite in conjunction with S(3) Bond demonstrated an acceptable clinical performance up to 3 years. …

Journal of dentistry 38(3), 191-200, 2010-03

CrossRef IR
2

Current opinion of therapeutic drugs for mitochondrial disease and investigator-mediated clinical trial of L-arginine on MELAS [in Japanese]

古賀靖敏

医学のあゆみ 232(6), (2787) 759〜764, 2010/2/6
3

Clinical Effectiveness of Acupuncture and Moxibustion Applied to Strongly Reactive Points : Randomized Controlled Trial Regarding Clinical Efficacy [in Japanese]

Watanabe Katsuyuki

The bulletin of Meiji University of Integrative Medicine (02), 11-23, 20100202

CiNii Link1
4

Effect of intervention for life style factors on chronic low back pain [in Japanese]

中村英一郎 , 中村利孝

Clinical orthopaedic surgery 45(1), 5〜8, 2010/1

Ichushi
5

Global Clinical Trialへの挑戦アジアンスタディの推進はドラッグラグ解消の一手 [in Japanese]

望月英梨 , ルベールエリック , ロッシーブルーノ

Medical information express 38(1), (501) 48〜50, 2010/1
6

Standard-Dose Statin Therapy Provides Incremental Clinical Benefits in Normocholesterolemic Diabetic Patients

Kojima Sunao , Sakamoto Tomohiro , Ogawa Hisao , Kitagawa Akira , Matsui Kunihiko , Shimomura Hideki , Kimura Kazuo , Ogata Yasuhiro , Sakaino Naritsugu , The Multicenter Study for Aggressive Lipid-lowering Strategy by HMG-CoA Reductase Inhibitors (MUSASHI) investigators

… Methods and Results: A prospective, randomized, open, blinded-endpoint trial was conducted from 2002 to 2004 at 55 hospitals in Japan to evaluate the effect of statins on subsequent cardiovascular events. … Clinical parameters were comparable between DM and non-DM groups. … Conclusions: Standard-dose statin therapy provides incremental clinical benefits in DM patients with normal cholesterol levels compared with non-DM patients. …

Circulation Journal advpub(0), 1002150613, 2010

CrossRef J-STAGE
7

A Randomized Controlled Open Comparative Trial of Varenicline vs Nicotine Patch in Adult Smokers: : Efficacy, Safety and Withdrawal Symptoms (The VN-SEESAW Study)

Tsukahara Hitomi , Noda Keita , Saku Keijiro

… The present study was a randomized controlled trial of varenicline vs nicotine patch in adult smokers for comparison of efficacy, safety and withdrawal symptoms. …

Circulation Journal advpub(0), 1002100610, 2010

CrossRef J-STAGE
8

Pharmacological Evaluation of Analgesic Effects of the Cholecystokinin2 Receptor Antagonist Z-360 in Mouse Models of Formalin- and Cancer-Induced Pain

Yoshinaga Koji , Horii Takayuki , Hamano Hiroki , Eta Runa , Ozaki Tomoko , Orikawa Yuki , Yoshii Kazuyoshi , Kawabata Yoshihiro , Hori Yuko , Seto Koichi , Takei Mineo , Kuraishi Yasushi

… Z-360, a novel cholecystokinin2 (CCK2) receptor antagonist, has been developed as a therapeutic drug for pancreatic cancer and showed pain relief action in phase Ib/IIa clinical trial. …

Biological & Pharmaceutical Bulletin 33(2), 244-248, 2010

CrossRef J-STAGE
9

Inflammation in Atherosclerosis: : Transition From Theory to Practice

Libby Peter , Okamoto Yoshihisa , Rocha Viviane Z. , Folco Eduardo

… Recent data link obesity, inflammation, and modifiers of atherosclerotic events, a nexus of growing clinical concern given the worldwide increase in the prevalence of obesity. … The recent JUPITER trial supports the clinical utility of an assessment of inflammatory status in guiding intervention to limit cardiovascular events. …

Circulation Journal advpub(0), 1001060571, 2010

CrossRef J-STAGE
10

Effectiveness of Aquatic Exercise and Balneotherapy: A Summary of Systematic Reviews Based on Randomized Controlled Trials of Water Immersion Therapies

Kamioka Hiroharu , Tsutani Kiichiro , Okuizumi Hiroyasu , Mutoh Yoshiteru , Ohta Miho , Handa Shuichi , Okada Shinpei , Kitayuguchi Jun , Kamada Masamitsu , Shiozawa Nobuyoshi , Honda Takuya

… Background: The objective of this review was to summarize findings on aquatic exercise and balneotherapy and to assess the quality of systematic reviews based on randomized controlled trials.Methods: Studies were eligible if they were systematic reviews based on randomized clinical trials (with or without a meta-analysis) that included at least 1 treatment group that received aquatic exercise or balneotherapy. …

Journal of Epidemiology advpub(0), 0910270113, 2010

CrossRef J-STAGE
11

Comparison of Antiarrhythmics Used in Patients With Paroxysmal Atrial Fibrillation: : Subanalysis of J-RHYTHM Study

Aizawa Yoshiyasu , Kohsaka Shun , Suzuki Shinya , Atarashi Hirotsugu , Kamakura Shiro , Sakurai Masayuki , Nakaya Haruaki , Fukatani Masahiko , Mitamura Hideo , Yamazaki Tsutomu , Yamashita Takeshi , Ogawa Satoshi , J-RHYTHM Investigators

… Background: The J-RHYTHM (Japanese Rhythm Management Trial for Atrial Fibrillation) study demonstrated the benefit of rhythm-control compared with rate-control in Japanese patients with paroxysmal atrial fibrillation (AF), according to AF-specific quality of life scores. … The clinical outcome according to choice of initial antiarrhythmic agent (AA) was assessed by Kaplan-Meier survival curve, and further adjusted by Cox-regression hazard model. …

Circulation Journal advpub(0), 0911300527, 2010

CrossRef J-STAGE
12

Practical considerations in sample size determination of Japanese subgroup for a multi-regional oncology clinical trial

Ogawa Sachio , Sekiguchi Risa , Uesaka Hiroyuki

Japanese journal of biometrics 30(2), 81〜91, 2009/12
13

Randomized controlled study investigating viral suppression and serological response following pre-S1/pre-S2/S vaccine therapy combined with lamivudine treatment in HBeAg-positive patients with chronic hepatitis B.

Hoa Pham Thi Le , Huy Nguyen Tien , Thu Le The , Nga Cao Ngoc , Nakao Kazuhiko , Eguchi Katsumi , Chi Nguyen Huu , Hoang Bui Huu , Hirayama Kenji

… We established a randomized, controlled clinical trial to compare the responses of three different treatment groups: those receiving vaccine monotherapy, lamivudine monotherapy, or combination treatment. …

Antimicrobial agents and chemotherapy 53(12), 5134-5140, 2009-12

CrossRef IR
14

LONGITUDINAL AND INCOMPLETE CLINICAL STUDIES

Molenberghs Geert , Verbeke Geert

… Generally, commonly used methods to analyze incomplete longitudinal clinical trial data include complete-case (CC) analysis and an analysis using the last observation carried forward (LOCF). …

Journal of the Japanese Society of Computational Statistics 22(1), 1-32, 20091200

CiNii PDF
15

Trial of clinical evaluation of registration method based on intraoperative measurement in the body [in Japanese]

金守恒志 , 黒田嘉宏 , 滝内秀和 [他]

IEICE technical report 109(270), 7〜12, 2009/11/11
16

THERAPEUTIC STRATEGIES FOR RESECTABLE MALIGNANT PLEURAL MESOTHELIOMA [in Japanese]

Hasegawa Seiki

Journal of Japan Surgical Society 110(6), 338-342, 20091101

CiNii PDF Ichushi
17

Quality control and quality assurance in clinical trials [in Japanese]

冨井裕子 , 福田治彦

Clinical oncology 4(5), (23) 473〜479, 2009/11

Ichushi
18

ToGA trial [in Japanese]

大津敦 , 土井俊彦

Clinical oncology 4(5), (23) 459〜466, 2009/11

Ichushi
19

Correlation between progression-free survival and overall survival in advanced gastric cancer and advanced colorectal cancer [in Japanese]

布施望

Clinical oncology 4(5), (23) 424〜429, 2009/11

Ichushi
20

Revised RECIST guideline (version 1.1) [in Japanese]

渡辺裕一

Clinical oncology 4(5), (23) 397〜402, 2009/11

Ichushi

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