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Comprehensive miRNA expression analysis in peripheral blood can diagnose liver disease
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Yoshiki Murakami
,
Hidenori Toyoda
,
Toshihito Tanahashi
,
Junko Tanaka
,
Takashi Kumada
,
Yusuke Yoshioka
,
Nobuyoshi Kosaka
,
Takahiro Ochiya
,
Y-H. Taguchi
… Background: miRNAs circulating in the blood in a cell-free form have been acknowledged for their potential as readily accessible disease markers. … Presently, histological examination is the golden standard for diagnosing and grading liver disease, therefore non-invasive options are desirable. … Here, we investigated if miRNA expression profile in exosome rich fractionated serum could be useful for determining the disease parameters in patients with chronic hepatitis C (CHC). …
IPSJ SIG technical reports 2012-BIO-32(12), 1-6, 2012-11-29
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