Search Results:　 1-20 of 20

KAMIGAUCHI Miyoko , KAWANISHI Kazuko , OHISHI Hirofumi , ISHIDA Toshimasa

… The enhancing effects of α-, β-, and γ-cyclodextrins (CyDs) on the aqueous extraction of ephedrine and berberine from the natural medicines were investigated in HPLC analysis, and the greatest effect was observed for β- and γ-CyDs. … To clarify the structural basis of such an increased extraction effect with β-CyD, possible interaction modes of (1R,2S)-ephedrine with α-, β-, and γ-CyDs were investigated using molecular dynamic simulations in an aqueous solution system. …

Chemical & pharmaceutical bulletin 55(5), 729-733, 2007-05-01

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KAKIUCHI Nobuko , NAKAJIMA Ikumi , KURITA Yukimasa , LONG Changfeng , CAI Shaoqing , MIKAGE Masayuki

… Specimens taken from those Ephedra fields were genetically and morphologically analyzed, and their ephedrine alkaloid content was examined. … On the other hand, the profile of the ephedrine alkaloid content was clearly correlated with the result of direct sequencing of the trn L/F region; … sinica-type sequence contained more ephedrine than pseudoephedrine, and the specimens of the E. …

Biological & pharmaceutical bulletin 29(4), 746-749, 2006-04-01

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KIM Hye Kyong , CHOI Young Hae , CHANG Wen-Te , VERPOORTE Robert

… Four ephedrine analogues such as ephedrine, pseudoephedrine, methylephedrine, and methylpseudo-ephedrine were determined by ^1H-NMR from Ephedra species. … The amount of each alkaloid was calculated by the relative ratio of the intensity of H-1 signal to the known amount of internal standard, 200 μg of anthracene. … This method allows rapid determination of the quantity of four ephedrine alkaloids from Ephedra species. …

Chemical & pharmaceutical bulletin 51(12), 1382-1385, 2003-12-01

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TANAKA TOSHIHIRO , OHBA KOJI , KAWAHARA KAZUHITO , SAKAI EIJI

… Ephedra herbs, imported from China, Hong Kong, Pakistan and Russia (including old U.S.S.R.) in the past 19 years were assayed for their ephedrine-type alkaloid contents by HPLC. … No regional differences were observed in the total alkaloid contents among the crude drugs from different places. … Most of the crude drug samples contained ephedrine and pseudoephedrine as the main alkaloids, but some contained considerable amounts of norephedrine and methylephedrine. …

Natural medicines 49(4), 418-424, 1995-12-20

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NOGUCHI MAMORU , HOSODA KATSUKO , SUZUKI HIDEYO

… A new method for simultaneous determination of ephedrine, pseudoephedrine and methylephedrine in the decoction of Ephedrae Herba by normal phase high-performance liquid chromatography is reported. … By using silica gel column and the mixture of n-hexane, ethanol and ammonia (125 : 75 : 1) as a mobile phase, each alkaloid was well separated within 10 min. Optimal wavelength for detection was found to be 220 nm by three dimensional observation. …

Journal of the Pharmaceutical Society of Japan 107(5), 372-376, 1987-05-25

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KASAHARA YOSHIMASA , HIKINO HIROSHI , YANG LING-LING , YEN KUN-YING

… The contents of ephedrine alkaloids in various kind of Ephedra internodes and nodes were determined by isotachophoresis. … The alkaloid contents in Ephedra nodes (average: 0.287%) were less than those in Ephedra internodes (average: 0.687%), confirming that the differences in pharmacological actions of Ephedra nodes and internodes were attributed to the differences of their alkaloid contents. …

The Japanese journal of pharmacognosy 39(2), 142-145, 1985-06-20

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NOGUCHI MAMORU , KUBO MICHINORI , NAKA YORIKO

… The recovery of ephedrine or alkaloids from the decoction of ephedra herb added with glycyrrhiza radix, cinnamon cortex, armeniac seeds, or their mixture (Maoo-to without ephedra herb) ranged between 55 and 83%. … The pH of these decoctions were below 7.0,where ephedrine and methylephedrine did not distill out with steam during decoction. … It was assumed that the decrease in alkaloid recovery in Maoo-to originated in adsorption of these alkaloids on crude drug materials in the decoction solution. …

Journal of the Pharmaceutical Society of Japan 98(7), 923-928, 1978-07-25

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Shibata Shoji , Imaseki Izumi , Yamazaki Mikio

… It was proved that formate labeled with ^<14>C is incorporated into γ-methyl and Nmethyl groups in l-ephedrine molecule in Ephedra distachya. … The mechanism of biosynthesis of ephedrine coupling with the C_1-fragment incorporation is discussed. …

Pharmaceutical bulletin 5(6), 594-597, 1957-12-20

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SHIBATA Shoji , IMASEKI Izumi

… By the hydroponic cultivation of Ephedra plant using ^<15>N-labeled amino acids as the nitrogen source, it has been shown that phenylalanine takes part as a precursor in the biosynthesis of l-ephedrine. …

Pharmaceutical bulletin 4(4), 277-280, 1956-08-25

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