Search Results:　 1-20 of 340

1

Ginsenoside Rh1 Ameliorates High Fat Diet-Induced Obesity in Mice by Inhibiting Adipocyte Differentiation

Gu Wan , Kim Kyung-Ah , Kim Dong-Hyun

Biological & pharmaceutical bulletin 36(1), 102-107, 2013-01-00
2

Cytochrome P450 CYP716A53v2 Catalyzes the Formation of Protopanaxatriol from Protopanaxadiol During Ginsenoside Biosynthesis in Panax Ginseng

HAN Jung-Yeon , HWANG Hwan-Su , CHOI Su-Wan , KIM Hyun-Jung , CHOI Yong-Eui

Plant and cell physiology 53(9), 1535-1545, 2012-09-01

References (42)
3

Cytochrome P450 CYP716A53v2 Catalyzes the Formation of Protopanaxatriol from Protopanaxadiol During Ginsenoside Biosynthesis in Panax Ginseng

Han Jung-Yeon , Hwang Hwan-Su , Choi Su-Wan 他

Plant and Cell Physiology 53(9), 1535-1545, 2012-09-00
4

Improving effects of Red Ginseng and its saponin constituents on blood fluidity

Murata Kazuya , Tsukioka Yasuyuki , Nakao Kikuyo 他

Journal of traditional medicines 29(4), 169-178, 2012-00-00
5

Four New Triterpenoid Saponins from the Leaves of Panax japonicus Grown in Southern Miyazaki Prefecture (4)

YOSHIZAKI Kouichi , DEVKOTA Hari Prasad , YAHARA Shoji

… (2), chikusetsusaponin LM5 (3), chikusetsusaponin LM6 (4), and twenty known triterpenoid saponins such as ginsenoside Rb3 (5), ginsenoside Rc (6), ginsenoside Rd (7), ginsenoside Re (8), ginsenoside Rg1 (9), ginsenoside F3 (10), ginsenoside F5 (11), ginsenoside F6 (12), chikusetsusaponin IVa (13), chikusetsusaponin V (14), chikusetsusaponin L5 (15), chikusetsusaponin …

Chemical and Pharmaceutical Bulletin, 2012

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6

Effect of Notoginseng Extracts and Its Components on Lipopolysaccharide and Galactosamine Mixture-induced Impaired Hepatic Function in Mice [in Japanese]

Komatsu Ken-ichi , Tanaka Hiroko , Nakagawa Daisuke , Kawashima Keiko

… Extracts of notoginseng or its components (ginsenoside Rb1 and ginsenoside Rg1) were orally administered 2 h before LPS/GalN injection. …

YAKUGAKU ZASSHI 132(7), 831-836, 2012

J-STAGE Ichushi Web CrossRef
7

Metabolism of Ginsenoside Rb1 by Human Intestinal Microflora and Cloning of Its Metabolizing β-D-Glucosidase from Bifidobacterium longum H-1

Jung Il-Hoon , Lee Jeong Hoon , Hyun Yang-Jin , Kim Dong-Hyun

… To understand the role of intestinal microflora in expressing the pharmacological effect of ginsenoside Rb1, the metabolic activity of ginsenoside Rb1 by 148 fecal specimens was measured and its metabolizing β-glucosidase was cloned. … The average activities for p-nitrophenyl-β-D-glucopyranoside and ginsenoside Rb1 were 0.097±0.059 μmol/min/mg and 0.311±0.118 pmol/min/mg, respectively. …

Biological and Pharmaceutical Bulletin 35(4), 573-581, 2012

J-STAGE Ichushi Web CrossRef
8

Anti-apoptotic Function and Mechanism of Ginseng Saponins in Rattus Pancreatic β-Cells

Chen Fang , Chen Yuewen , Kang Xincong , Zhou Zhiguang , Zhang Zhixu , Liu Dongbo

… Ginseng has been used as an anti-diabetic herb for several thousand years in Asia with ginsenoside Rg1 and ginsenoside Rb1 as important active ingredients. … In this study, we demonstrated ginsenoside Rg1 and Rb1 protect β-cells from high glucose/cytokine-induced pancreatic β-cell apoptosis via inhibiting nitric oxide (NO) production and regulating apoptosis-related genes. …

Biological and Pharmaceutical Bulletin 35(9), 1568-1573, 2012

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9

Ginsenoside Rg3 Attenuates Microglia Activation Following Systemic Lipopolysaccharide Treatment in Mice

Park Sun-Min , Choi Moon-Suk , Sohn Nak-Won , Shin Jung-Won

… The present study investigated the immune modulatory effects of ginsenoside Rg3, a principle active ingredient in Panax ginseng, on pro-inflammatory cytokines and microglia activation in brain tissue induced by systemic lipopolysaccharide (LPS) treatment in C57BL/6 mice. … Based on this information, ginsenoside Rg3 was treated orally with 10, 20, and 30 mg/kg 1 h prior to the LPS (3 mg/kg, intraperitoneally (i.p.)) injection. …

Biological and Pharmaceutical Bulletin 35(9), 1546-1552, 2012

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10

New Triterpenoid Saponins from Fruit Specimens of Panax japonicus Collected in Toyama Prefecture and Hokkaido (2)

Yoshizaki Kouichi , Murakami Morikazu , Fujino Hiroharu , Yoshida Naotoshi , Yahara Shoji

… MEYER, collected in Toyama prefecture, Japan, and five new dammarane-type triterpenoid saponins, chikusetsusaponin FT1 (1), chikusetsusaponin FT3 (3), chikusetsusaponin FT4 (4), chikusetsusaponin FH1 (5), chikusetsusaponin FH2 (6), and eight known triterpenoid saponins, ginsenoside Re (7), chikusetsusaponin FK5 (9), chikusetsusaponin FK2 (10), chikusetsusaponin FK3 (11), chikusetsusaponin LN4 (12), 28-desglucosylchikusetsusaponin IVa (13), chikusetsusaponin IVa (14), and chikusetsusaponin V (15), were isolated from the fruits of P. …

Chemical and Pharmaceutical Bulletin 60(6), 728-735, 2012

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11

New Triterpenoid Saponins from Fruits Specimens of Panax japonicus Collected in Kumamoto and Miyazaki Prefectures (1)

Yoshizaki Kouichi , Yahara Shoji

… FK3 (3), chikusetsusaponin FK4 (4), chikusetsusaponin FK5 (5), chikusetsusaponin FK6 (6), and chikusetsusaponin FK7 (7), and eleven known triterpenoid saponins, ginsenoside Rb3 (9), ginsenoside Rc (10), chikusetsusaponin VI (11), ginsenoside Re (12), ginsenoside Rg1 (13), pseudo-ginsenoside RS1 (14), notoginsenoside R1 (15), chikusetsusaponin L5 (17), chikusetsusaponin L10 (18), chikusetsusaponin IVa (19), and chikusetsusaponin V (20), were isolated …

Chemical and Pharmaceutical Bulletin 60(3), 354-362, 2012

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12

Eastern Blotting Analysis and Isolation of Two New Dammarane-Type Saponins from American Ginseng

Tung Nguyen Huu , Shoyama Yukihiro

… Ginsenosides, the major active component of American ginseng, were analyzed using eastern blotting with anti-ginsenoside Rb1 and Rg1 monoclonal antibodies (MAbs). …

Chemical and Pharmaceutical Bulletin 60(10), 1329-1333, 2012

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13

The Cyt P450 Enzyme CYP716A47 Catalyzes the Formation of Protopanaxadiol from Dammarenediol-II During Ginsenoside Biosynthesis in Panax ginseng

HAN Jung-Yeon , KIM Hyun-Jung , KWON Yong-Soo , CHOI Yong-Eui

Plant and Cell Physiology 52(12), 2062-2073, 2011-12-01

References (40) Cited by (1)
14

Ginsenoside Rg3 inhibits CXCR_4 expression and related migrations in a breast cancer cell line

CHEN Xiao-ping , QIAN Lin-lin , JIANG Hong , CHEN Jiang-hua

International journal of clinical oncology 16(5), 519-523, 2011-10-01

References (39)
15

Simultaneous Enrichment of Deglycosylated Ginsenosides and Monacolin K in Red Ginseng by Fermentation with Monascus pilosus

HONG Sung-Yun , OH Jee-Hwan , LEE Inhyung

To improve its bioavailability and pharmacological effects in humans, red ginseng was fermented with a newly isolated fungus, <I>Monascus pilosus</I> KMU103. Most of the ginsenosides were …

Bioscience, Biotechnology, and Biochemistry 75(8), 1490-1495, 2011-08-23

J-STAGE CrossRef References (41)
16

Single-chain variable fragment antibody against ginsenoside Re as an effective tool for the determination of ginsenosides in various ginsengs

PONGKITWITOON Benyakan , SAKAMOTO Seiichi , MORINAGA Osamu , JUENGWATANATRAKUL Thaweesak , SHOYAMA Yukihiro , TANAKA Hiroyuki , MORIMOTO Satoshi

Journal of natural medicines 65(1), 24-30, 2011-01-20

References (17)
17

Intranasal Ginsenoside Rb1 Targets the Brain and Ameliorates Cerebral Ischemia/Reperfusion Injury in Rats

Lu Tingting , Jiang Yongjun , Zhou Zhiming , Yue Xuanye , Wei Ning , Chen Zhaoyao , Ma Minmin , Xu Gelin , Liu Xinfeng

… Ginsenoside Rb1 (GRb1) has been shown to benefit many central nervous system (CNS) disorders, including stroke. …

Biological and Pharmaceutical Bulletin 34(8), 1319-1324, 2011

J-STAGE Ichushi Web CrossRef
18

Rb1 Protects Endothelial Cells from Hydrogen Peroxide-Induced Cell Senescence by Modulating Redox Status

Liu Ding-Hui , Chen Yan-Ming , Liu Yong , Hao Bao-Shun , Zhou Bin , Wu Lin , Wang Min , Chen Lin , Wu Wei-Kang , Qian Xiao-Xian

… In the present study we aimed to investigate whether ginsenoside Rb1, a major constituent of ginseng, protects endothelial cells from H2O2-induced endothelial senescence. …

Biological and Pharmaceutical Bulletin 34(7), 1072-1077, 2011

J-STAGE Ichushi Web CrossRef
19

Anti-complementary Ginsenosides Isolated from Processed Ginseng

Lee Jin Gyun , Baek Seung Hoon , Lee Yong Yook , Park Seo Young , Park Jeong Hill

… Activity-guided fractionation was used to isolate four ginsenosides, namely ginsenoside Rg6, F4, Rk3, and Rh4. … Ginsenoside Rk3 and Rh4 had a 3 fold higher inhibition activity than rosmarinic acid which was used as a positive control while ginsenoside Rg6 and F4 showed only mild effects similar to that of the positive control. …

Biological and Pharmaceutical Bulletin 34(6), 898-900, 2011

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20

Efficient silkworm expression of single-chain variable fragment antibody against ginsenoside Re using Bombyx mori nucleopolyhedrovirus bacmid DNA system and its application in enzyme-linked immunosorbent assay for quality control of total ginsenosides

SAKAMOTO Seiichi , PONGKITWITOON Benyakan , NAKAMURA Seiko , MAENAKA Katsumi , TANAKA Hiroyuki , MORIMOTO Satoshi

Journal of Biochemistry 148(3), 335-340, 2010-09-01

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