Search Results:　 1-20 of 421

1

Chemokine-dependent T cell migration requires aquaporin-3-mediated hydrogen peroxide uptake.

Hara-Chikuma Mariko , Chikuma Shunsuke , Sugiyama Yoshinori , Kabashima Kenji , Verkman Alan S , Inoue Shintaro , Miyachi Yoshiki

… Coincidentally, AQP3-deficient mice are defective in the development of hapten-induced contact hypersensitivity, which is attributed to the impaired trafficking of antigen-primed T cells to the hapten-challenged skin. …

The Journal of experimental medicine 209(10), 1743-1752, 2012-09-24

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2

Red Ginseng Inhibits Scratching Behavior Associated With Atopic Dermatitis in Experimental Animal Models

SAMUKAWA Keiichi , IZUMI Yasukatsu , SHIOTA Masayuki , NAKAO Takafumi , OSADA OKA Mayuko , MIURA Katsuyuki , IWAO Hiroshi

Pruritus is a severe symptom that is difficult to treat in atopic dermatitis patients. Red ginseng (RG), a natural medicine, has various biological activities such as anti-inflammatory effects. In thi …

Journal of Pharmacological Sciences 118(3), 391-400, 2012-03-20

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3

Development of a Competitive ELISA for the Detection of a Furaltadone Marker Residue, 3-Amino-5-Morpholinomethyl-2-Oxazolidinone (AMOZ), in Cultured Fish Samples

SHEU Shi-Yuan , TAI Yung-Te , LI Wen-Ren , LEI Yi-Chih , HSIEH Kuan-Huei , LIN Chiu-Yueh , CHENG Chu-Chen , CHANG Tong-Hsuan , KUO Tzong-Fu

… Polyclonal rabbit antibodies were produced with a new immunogen hapten, 2-NP-HXA-AMOZ. …

Journal of Veterinary Medical Science 74(11), 1439-1446, 2012

J-STAGE CrossRef
4

The Rhizomes of Alisma orientale and Alisol Derivatives Inhibit Allergic Response and Experimental Atopic Dermatitis

Lee Je Hyeong , Kwon Oh Song , Jin Hong-Guang , Woo Eun-Rhan , Kim Yeong Shik , Kim Hyun Pyo

… In addition, AOE (200 mg/kg/d) was for the first time found to considerably alleviate hapten-induced dermatitis symptoms in NC/Nga mice, an animal model of atopic dermatitis. …

Biological and Pharmaceutical Bulletin 35(9), 1581-1587, 2012

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5

Acetaminophen enhances pruritus in a mouse model of contact dermatitis induced by suboptimal concentration of hapten

YAMAURA Katsunori , AKIYAMA Seri , ODA Manabu , SUWA Eriko , UENO Koichi

Acetaminophen (APAP) is one of the most commonly used drugs worldwide to reduce fever, particularly in children. It is generally considered to be a safe drug. However, a number of studies have shown t …

The Journal of Toxicological Sciences 36(5), 669-674, 2011-10-01

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6

Preparation of Monoclonal Antibody for Pesticide and Mycotoxin and Its Application to Food Analysis [in Japanese]

MIYAKE Shiro

食品を汚染する農薬やカビ毒などの低分子性物質の分析を目的に，モノクローナル抗体の調製，調製した抗体を用いた分析技術の開発，実試料による検証，製品化による技術の普及を行った．そのためには，分析現場で求められる目的仕様に対応した抗体調製と分析技術の開発が特に必要であった．抗体の調製では，免疫原性を得るための対象物質の修飾方法とともに，モノクローナル抗体のスクリーニング方法が重要で，これらの適切な選択に …

BUNSEKI KAGAKU 60(5), 389-398, 2011-05-05

J-STAGE Ichushi Web CrossRef References (25)
7

PEGylated antibody in organic media(BIOCHEMICAL ENGINEERING)

Liu Mingzhe , Xu Muye , Loh Xian Jun , Abe Hiroshi , Tsumuraya Takeshi , Fujii Ikuo , Li Jun , Son Tae Il , Ito Yoshihiro

… One was a monoclonal antibody (abzyme) that was prepared against a hapten mimicking a transition state of hydrolysis. …

Journal of bioscience and bioengineering 111(5), 564-568, 2011-05-00

CiNii Fulltext PDF - Paid References (20)
8

Stabilization Mechanism of Transition-state Hapten of a Catalytic Antibody by Molecular Dynamics Simulation

HARUNA Mitsumasa , UEDA Junko , KUROMIYA Kohji

Peptide science : proceedings of the ... Japanese Peptide Symposium 2010, 125, 2011-03-01

References (3)
9

Development of an ELISA to detect clenbuterol in pork using novel approach for hapten design(Analytical methods and clean-up,Poster,3) Regulatory Science and Residues) [in Japanese]

Bui A. Q. U. , Lee A. N. A. , Kennedy I. R. O. , Allan R. D. A.

Journal of pesticide science 36(1), 189-190, 2011-02-20

CiNii Fulltext PDF - Open Access
10

Seminar: Experimental techniques: Application of immunoassay for residue analysis of pesticides (part 1) Points of ELISA development for pesticide determination and its roper method for using [in Japanese]

三宅司郎

Journal of pesticide science 35(2), 176-180, 2010-05-20

CiNii Fulltext PDF - Open Access References (12)
11

Purification and Characterization of α-N-Acetylgalactosaminidases I and II from the Starfish Asterina amurensis

HARUN-OR-RASHID Md. , MATSUZAWA Tomomi , SATOH Youichi , SHIRAISHI Takayuki , ANDO Masayuki , SADIK Golam , UDA Yutaka

… α-GalNAcase I and II both hydrolyzed terminal α-<I>N</I>-acetylgalactosaminyl linkages of the natural compounds investigated: Forssman hapten glycolipid, blood group A active oligosaccharide and GalNAc-α1-<I>O</I>-serine. …

Bioscience, Biotechnology, and Biochemistry 74(2), 256-261, 2010-02-23

J-STAGE CrossRef References (30)
12

Role of intestinal Bifidobacterium pseudolongum in dietary fructo-oligosaccharide inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice

Sasajima Naho , Ogasawara Toru , Takemura Naoki , Fujiwara Reiko , Watanabe Jun , Sonoyama Kei

… pseudolongum administration increased hapten-specific IgGI, while dietary FOS decreased IgG2a in sera. … pseudolongum decreased interferon-γ production and increased IL-10 production in cervical lymph node cells restimulated with hapten in vitro. …

Br J Nutr 103(4), 539-548, 2010-02-00

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13

Low zone tolerance requires ICAM-1 expression to limit contact hypersensitivity elicitation.

Komura Kazuhiro , Iwata Yohei , Ogawa Fumihide , Yoshizaki Ayumi , Yamaoka Toshifumi , Akiyama Yuichiro , Hara Toshihide , Hasegawa Minoru , Fujimoto Manabu , Sato Shinichi

… The blockade of IL-10, a possible mediator of LZT, produced by hapten-specific suppressor cells, abrogated LZT and restored ICAM-1 upregulation. …

The Journal of investigative dermatology 129(11), 2661-2667, 2009-11-00

IR
14

Low Zone Tolerance Requires ICAM-1 Expression to Limit Contact Hypersensitivity Elicitation

Komura Kazuhiro , Yanaba Koichi , Horikawa Mayuka , Ogawa Fumihide , Fujimoto Manabu , Tedder Thomas F. , Sato Shinichi

… The blockade of IL-10, a possible mediator of LZT, produced by hapten-specific suppressor cells, abrogated LZT and restored ICAM-1 upregulation. …

Journal of Investigative Dermatology 129(11), 2661-2667, 2009-11-00

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15

Effect of Administration of Adlay Leaves on 2,4,6-trinitro-1-chlorobenzene-induced Chronic Dermatitis in Mice

HAYASHI Hirotaka , TAKEGAWA Masanori , TSUZUKI Masao , MATSUZAWA Kazuyuki , YOSHIZAWA Minako , BARLA Florin , YUKINO Tsugiyo , MIEDA Takahiro , INUI Hiroshi , NAKANO Yoshihisa , ENOMOTO Toshiki

… The hapten 2,4,6-trinitro-1-chlorobenzene (TNCB) was applied to the right ear of mice daily for 28 days to generate a model of chronic dermatitis. …

Food Science and Technology Research 15(5), 525-530, 2009-09-01

J-STAGE CrossRef References (38)
16

Highly sensitive detection of 2,4,6-trinitrotoluene using surface plasmon resonance sensor with displacement immunoassay [in Japanese]

ONODERA Takeshi , Mizuta Yutaka , HORIKAWA Kazuhiko , MATSUMOTO Kiyoshi , MIURA Norio , TOKO Kiyoshi

現在,爆発物の探知には訓練された犬や金属探知機,X線装置などが使用されているが,これらの方法には使用場面によっては適用が難しい場合がある.そこで本研究では,ポータブルで高感度な爆発物探知装置の開発を目的として,表面プラズモン共鳴(SPR)免疫センサを用いて,爆薬であるトリニトロトルエン(TNT)の高感度検出手法の検討を行った.このとき置換法と呼ばれる検出方法を用い,センサ表面に固定化するハプテンの …

IEICE technical report. Electron devices 109(157), 23-28, 2009-07-23

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17

Preparation of Anti-dinitrotoluene Polyclonal Antibody and Effect of the Hapten Spacer Length in Coating Antigen on Immunoassay Sensitivity

Nagatomo Kazutaka , Matsumoto Kiyoshi , Ishitobi Sachiko , Koga Mao , Toko Kiyoshi , Miura Norio , 長友一剛 , 松本清 , 石飛幸子 , 古賀麻央 , 都甲潔 , 三浦則雄

A polyclonal antibody against 2,4-dinitrotoluene (2,4-DNT) has been raised in rabbit, and the antibody was used to detect 2,4-DNT using an enzyme-linked immunosorbent assay (ELISA) method. A 2,4-dinit …

Journal of the Faculty of Agriculture, Kyushu University 54(1), 165-171, 2009-02-27

IR
18

Prolonged Suppression of Chick Humoral Immune Response by Antigen Specific Maternal Antibody

ELAZAB Mohamed Fahmy Abou , FUKUSHIMA Yuji , HORIUCHI Hiroyuki , MATSUDA Haruo , FURUSAWA Shuichi

Although the inhibitory effect of maternal antibodies on active immunization of neonates has been extensively documented, much less attention has been devoted on the exact level of these antibodies wh …

Journal of Veterinary Medical Science 71(4), 417-424, 2009

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19

Development and characterization of enzyme-linked immunosorbent assay for aflatoxin B_1 measurement in urine sample using penicillinase as label

Paknejad Malihe , Rasaee Mohammad Javad , Mohammadnejad Javad , Pouramir Mehdi , Rajabibazl Masoume , Kakhki Mohammad

… The antibody prepared in this study showed minimal cross-reaction with structurally related molecules being affected by homology and heterology of the assay system that is the site of conjugation of carrier protein for antibody production using the hapten BSA conjugate and the site of enzyme conjugated on the hapten molecule used as tracer as well as direct and indirect coating of antibody on the surface of microtiter plat. …

Journal of toxicological sciences 33(5), 565-573, 2008-12-01

CiNii Fulltext PDF - Open Access J-STAGE Ichushi Web CrossRef References (31)
20

Mechanism of drug allergy [in Japanese]

橋爪秀夫

Clinical immunology & allergology 50(5), 551-559, 2008-11-00

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