検索結果:　1622件中 1-20 を表示

1

Effects of Hydroxy Pentacyclic Triterpene Acids from Forsythia viridissima on Asthmatic Responses to Ovalbumin Challenge in Conscious Guinea Pigs

Lee Ji Yun , Moon Hee , Kim Chang Jong

… Histamine and phospholipase A2 activity in BALF were significantly decreased by HTAs at 12.5 mg/kg, whereas eosinophil peroxide (EPO) activity in BALF and recruitment of eosinophils were significantly decreased by HTAs at 25 mg/kg, as well as improvement of pathological changes. … These results indicate HTAs had anti-asthmatic activity by decreasing of sRaw, and eosinophil recruitment and release of inflammatory mediators into the lungs. …

Biological & Pharmaceutical Bulletin 33(2), 230-237, 2010

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2

血液検査 (特集アレルギー疾患病態--コントロールから予防と治癒を目指して) -- (診断)

加藤政彦

日本臨床 67(11), (965) 2100〜2104, 2009/11

医中誌
3

Effects of Bidens pilosa L. var. radiata SCHERFF treated with enzyme on histamine-induced contraction of guinea pig ileum and on histamine release from mast cells

MATSUMOTO Takayuki , HORIUCHI Masako , KAMATA Katsuo , SEYAMA Yoshiyuki

… The medical mechanism against type I allergies is to block the release or production of chemical mediators from mast cells or to block the H_1-receptor signaling. … radiata SCHERFF treated with the enzyme cellulosine (eMMBP) was dependent on the inhibition of histamine release from mast cells. …

日本平滑筋学会機関誌 45(2&3), 75-86, 20090600

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4

Shishihakuhito, a traditional Chinese medicine for atopic dermatitis, inhibits IgE-mediated histamine release from rat RBL-2H3 basophilic leukocyte cells

WAKABAYASHI Mie , SAKURAI Eiko , YANAI Kazuhiko , UMEMURA Kazuhiro , YOSHIDA Masaaki , OHIZUMI Yasushi , 山國徹

梔子柏皮湯は,山梔子,黄柏,甘草の3つの構成生薬より熱水抽出した水製乾燥エキスであり,アトピー性皮膚炎の有効な漢方治療薬である。本研究では,梔子柏皮湯の作用メカニズムを解明するため,ラット好塩基球性白血病細胞(RBL-2H3)において,アレルギー反応のケミカルメデイエーターであるヒスタミン遊離への梔子柏皮湯の影響を検討した。さらに,COX-2などの炎症性遺伝子の転写誘導において中心的な役割を演じる …

和漢医薬学雑誌 26(1), 44-49, 20090228

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5

Shishihakuhito, a traditional Chinese medicine for atopic dermatitis, inhibits IgE-mediated histamine release from rat RBL-2H3 basophilic leukocyte cells

WAKABAYASHI Mie , SAKURAI Eiko , YANAI Kazuhiko , UMEMURA Kazuhiro , YOSHIDA Masaaki , OHIZUMI Yasushi , YAMAKUNI Tohru

Journal of traditional medicines 26(1), 44-49, 20090228

参考文献17件
6

スギ花粉入りカプセル服用後にアナフィラキシーショックを呈した症例

榎本雅夫 , 森田裕司 , 齋藤明美 , 安枝浩

スギ花粉症の有病率は,日本の「国民病」といえる程に高い.一般的な治療には,マスクやメガネなどを使用したスギ花粉の回避によるセルフケアと第2世代抗ヒスタミン薬や鼻噴霧用ステロイド薬を用いたメディカルケアがある.しかし,医療機関を受診せず,いわゆる健康食品を利用した「セルフメディケーション」を行っている患者も多い.その1つに,スギ花粉をカプセルに詰めたものがある.2007年2月に,そのカプセル服用後に …

アレルギー 58(1), 39-44, 20090130

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7

アシタバの成分と系統育成

馬場きみ江 , 谷口雅彦 , 芝野真喜雄 , 南晴文

アシタバAngelica keiskei KOIDZUMIは八丈島を原産地とする日本固有のセリ科の大型多年草である．現地では古くから，野菜又は民間薬として利用されている．本植物は根，茎，葉に多量の黄色物質を含んでいるのが特徴である．著者等は植物学的形態と高速液体クロマトグラフィーによるクマリン成分のプロファイルに基づき，産地による比較分類を行った．またこの黄色成分の単離，構造解析を行い，10種の新 …

分析化学 58(12), 999-1009, 2009

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8

Methamphetamine- and 3,4-Methylenedioxymethamphetamine–Induced Behavioral Changes in Histamine H3–Receptor Knockout Mice

Okuda Tomohiro , Zhang Dongying , Shao He [他] , Okamura Nobuyuki , Takino Naoko , Iwamura Tatsunori , Sakurai Eiko , Yoshikawa Takeo , Yanai Kazuhiko

… Histamine H3 receptors inhibit the release of not only histamine itself, but also other neurotransmitters including dopamine. …

Journal of Pharmacological Sciences advpub(0), 0909250281, 2009

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9

Ellagic Acid Attenuates Immunoglobulin E-Mediated Allergic Response in Mast Cells

Choi Yun Ho , Yan Guang Hai

… Ellagic acid dose-dependently reduced histamine release and the expression and secretion of pro-inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6 in rat peritoneal mast cells (RPMC) activated by anti-DNP IgE. …

Biological & Pharmaceutical Bulletin 32(6), 1118-1121, 2009

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10

Anti-inflammatory Effect of Columbianetin on Activated Human Mast Cells

Jeong Hyun-Ja , Na Ho-Jeong , Kim Su-Jin [他] , Rim Hong-Kun , Myung Noh-Yil , Moon Phil-Dong , Han Na-Ra , Seo Jae-Uk , Kang Tae-Hee , Kim Jae-Joong , Choi Youngjin , Kang In-Cheol , Hong Seung-Heon , Kim You-Ah , Seo Young-Wan , Kim Hyung-Min , Um Jae-Young

… In the present study, we investigate the effect of Columbianetin on the production of histamine, interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor (TNF)-α and expression of cyclooxygenase-2 (COX-2) by using the human mast cell line (HMC-1). … In addition, the effect of Columbianetin was investigated on the histamine release from HMC-1 stimulated by substance P, which promotes histamine release. …

Biological & Pharmaceutical Bulletin 32(6), 1027-1031, 2009

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11

Silibinin Attenuates Mast Cell-Mediated Anaphylaxis-Like Reactions

Choi Yun Ho , Yan Guang Hai

… Silibinin dose-dependently reduced histamine release from RPMC activated by compound 48/80 or anti-DNP IgE. …

Biological & Pharmaceutical Bulletin 32(5), 868-875, 2009

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12

Effects of Benzylidenecyclopentanone Analogues of Curcumin on Histamine Release from Mast Cells

Nugroho Agung Endro , Ikawati Zullies , Sardjiman [他]

… Curcumin reportedly has anti-allergic effects and can inhibit the release of histamine from mast cells. … In the present study, fourteen benzylidenecyclopentanone analogues of curcumin were studied for their effects on histamine release from rat basophilic leukemia (RBL-2H3) cells. …

Biological & Pharmaceutical Bulletin 32(5), 842-849, 2009

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13

Histamine Release Inhibitory Activity of Piper nigrum Leaf(Pharmacognosy)

HIRATA Noriko , NARUTO Shunsuke , INABA Kazunori , ITOH Kimihisa , TOKUNAGA Masashi , IINUMA Munekazu , MATSUDA Hideaki

… PN-ext exhibited in vitro inhibitory effect on compound 48/80-induced histamine release from rat peritoneal mast cells. … Two lignans of PN-ext, (-) -cubebin (1) and (-)-3, 4-dimethoxy-3, 4-desmethylenedioxycubebin (2), were identified as major active principles having histamine release inhibitory activity. …

Biological & pharmaceutical bulletin 31(10), 1973-1976, 20081001

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14

ラット好塩基様RBL-2H3細胞におけるγ-アミノ酪酸(GABA)のヒスタミン遊離抑制作用

堀あゆみ , 原崇 , 本間香織 [他]

新潟大学農学部研究報告 61(1), 47〜51, 2008/9
15

Mosla dianthera Decreases Immediate-Type Allergic Reaction and Tumor Necrosis Factor-α Production

Kim Sang-Hyun , Jeon Hoon , Lee Soyoung , Son Hee-Young , Park Seung-Bin , Kim Mi-Sun , Choi Eun-Ju , Lim Jong-Pil , Eun Jae-Soon , Park Jeong-Suk , Shin Tae-Yong

… Stimulation of mast cells releases inflammatory mediators, such as histamine, and proinflammatory cytokines with immune regulatory properties. … AEMD dose dependently inhibited compound 48/80-induced systemic allergic reaction and serum histamine release in mice. … AEMD attenuated immunoglobulin E (IgE)-mediated skin allergic reaction and histamine release from mast cells. …

Journal of health science 54(4), 416-422, 20080801

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16

気道アレルギーでのアレルゲン検索法(プリックテストを含む)(アレルギー実践講座)

本島新司

気道アレルギー疾患の代表はアレルギー性鼻炎と気管支喘息である.症状,鼻汁や喀痰の細胞診(好酸球の検索),気道過敏性の検査などからこれらの疾患の診断はつけられる.治療の一環としてもアレルゲン検索が必要であるが,どのようにしてアレルゲンの推定,決定を行うか解説したい.

アレルギー 57(6), 693-698, 20080620

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17

Improvement of the Antiinflammatory and Antiallergic Activity of Bidens pilosa L. var. radiata SCHERFF Treated with Enzyme (Cellulosine)

Horiuchi Masako , Seyama Yoshiyuki

… Oral administration of eMMBP suspension inhibited dye exudation in rat skin induced by passive cutaneous anaphylaxis (PCA) and chemical mediators (histamine and substance P). … The effects of eMMBP on the inhibition of histamine release from mast cells induced by compound 48/80 or antigen-antibody reaction was stronger than that of the hot-water extract (HWex). …

Journal of health science 54(3), 294-301, 20080601

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18

Total Phenolic Content, Antioxidative, Anti-amylase, Anti-glucosidase, and Antihistamine Release Activities of Bangladeshi Fruits

HOSSAIN Sheikh Julfikar , TSUJIYAMA Iyo , TAKASUGI Mikako , ISLAM Md. Ashabul , BISWAS Rajat Shuvra , AOSHIMA Hitoshi

… indica and Phyllanthus acidus (star-gooseberry), all other extracts inhibited the release of histamine from the peritoneal exudate cells, with S. …

Food science and technology research 14(3), 261-268, 20080501

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19

Progress in Allergy Signal Research on Mast Cells : The Role of Histamine in Immunological and Cardiovascular Disease and the Transporting System of Histamine in the Cell

OHTSU Hiroshi

… Since its discovery in 1910, histamine has been regarded as one of the most important biogenic amines in the medical and biological fields. … This article summarizes the information about the role of histamine in allergic situations, atherosclerosis, and autoimmune encephalomyelitis, especially focusing on our study with histidine decarboxylase gene knockout mouse. … In the allergic bronchial asthma model, histamine positively controls eosinophilia but not bronchial hypersensitivity. …

Journal of pharmacological sciences 106(3), 347-353, 20080320

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20

The Influence of Mast Cell Mediators on Migration of SW756 Cervical Carcinoma Cells

RUDOLPH M. Isolde , BOZA Yadira , YEFI Roger , LUZA Sandra , ANDREWS Edilia , PENISSI Alicia , GARRIDO Pablo , ROJAS I. Gina

… Therefore, the specific effects of histamine and cannabinoids on SW756 migration and LAD2 activation were analyzed. … Histamine added to the in vitro assay of scratch wound healing either increased or inhibited SW756 migration rate by acting either on H1R or H4R, respectively. … The results suggest that mast cells could be contributing to cervical cancer cell invasion and spreading by the release of histamine and cannabinoids. …

Journal of pharmacological sciences 106(2), 208-218, 20080220

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