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1

Substitution of Glu122 by Glutamine Revealed the Function of the Second Water Molecule as a Proton Donor in the Binuclear Metal Enzyme Creatininase.

Yamashita Kinuyo , Nakajima Yoshitaka , Matsushita Hayato , Nishiya Yoshiaki , Yamazawa Ryuji , Wu Yu-Fan , Matsubara Futoshi , Oyama Hiroshi , Ito Kiyoshi , Yoshimoto Tadashi

… X-ray crystallographic study and the atomic absorption spectrometry analysis of the E122Q mutant-substrate complex revealed that the drastic decrease of the activity of the E122Q was caused by not only the loss of one Zn ion at the Metal1 site but also a critical function of Glu122, which most likely exists for a proton transfer step through Wat2. …

Journal of molecular biology 396(4), 1081-1096, 2010-03-05

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2

Improvement in the remaining activity of freeze-dried xanthine oxidase with the addition of a disaccharide-polymer mixture

Srirangsan Paveena , Kawai Kiyoshi , Hamada-Sato Naoko , Watanabe Manabu , Suzuki Toru , カワイキヨシ , ハマダ-サトウナオコ , ワタナベマナブ , スズキトル , シリランサアンパウィナー , 川井清司 , 濱田(佐藤) 奈保子 , 渡辺学 , 鈴木徹

… In order to improve the remaining activity of a practically important freeze-dried enzyme, xanthine oxidase (XOD), the effects of disaccharide (sucrose and trehalose), polymer (bovine serum albumin: BSA and dextran) and a mixture of them on the loss of XOD activity during freeze-drying and subsequent storage were investigated. … Although dextran showed no stabilizing effect on the freeze-dried XOD, the others protected XOD from the activity loss during freeze-drying to a certain extent. …

Food Chemistry 119(1), 209-213, 20100301

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3

Time-variable ice loss in Asian high mountains from satellite gravimetry

Matsuo Koji , Heki Kosuke

… Gravimetry by GRACE satellite during 2003-2009 suggests the average ice loss rate in this region of 47 ± 12 Gigaton (Gt) yr^[-1], equivalent to ~0.13 ± 0.04 mm yr^[-1] sea level rise. … This is twice as fast as the average rate over ~40 years before the studied period, and agrees with the global tendency of accelerating glacial loss. … Such ice loss rate varies both in time and space; …

Earth and Planetary Science Letters 290(1-2), 30-36, 2010-02-15

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4

Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome

Tanaka Mari , Asada Misako , Higashi Atsuko Y. , Nakamura Jin , Oguchi Akiko , Tomita Mayumi , Yamada Sachiko , Asada Nariaki , Takase Masayuki , Okuda Tomohiko , Kawachi Hiroshi , Economides Aris N. , Robertson Elizabeth , Takahashi Satoru , Sakurai Takeshi , Goldschmeding Roel , Muso Eri , Fukatsu Atsushi , Kita Toru , Yanagita Motoko , 柳田素子

腎不全治療の新しい可能性の発見－腎不全をきたす遺伝病、アルポート症候群はBMP阻害分子USAG-1欠損によって軽快し、腎不全に陥らない－. 京都大学プレスリリース. 2010-02-09. http://www.kyoto-u.ac.jp/ja/news_data/h/h1/news6/2009/100209_1.htmThe glomerular basement m …

Journal of Clinical Investigation, 2010-02-08

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5

VAV2 and VAV3 as Candidate Disease Genes for Spontaneous Glaucoma in Mice and Humans

Fujikawa Keiko , Iwata Takeshi , Inoue Kaoru , Akahori Masakazu , Kadotani Hanako , Fukaya Masahiro , Watanabe Masahiko , Chang Qing , Barnett Edward M. , Swat Wojciech

… Vav2/Vav3-deficient mice, and to a lesser degree Vav2-deficient mice, show early onset of iridocorneal angle changes and elevated intraocular pressure, with subsequent selective loss of retinal ganglion cells and optic nerve head cupping, which are the hallmarks of glaucoma. …

PLoS ONE 5(2), 9050, 2010-02-04

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6

食肉の品質特性の解析と応用 [in Japanese]

泉本勝利

… Deterioration of food becomes economic loss then results in environment load, so quality control is important. …

岡山大学農学部学術報告 99(1), 85-95, 2010-02-01

IR
7

Analysis on loss anisotropy of piezoelectrics with ∞ mm crystal symmetry

Zhuang Yuan , Ural Seyit O. , Tuncdemir Safakcan [他]

Japanese journal of applied physics 49(2), 021503-1〜6, 2010/2
8

A three-phase solar power conditioner using a single-phase PWM control method [in Japanese]

藤田英明 , 鈴木亮

IEEJ transactions on industry applications 130(2), 173〜180, 2010/2
9

Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates [in Japanese]

河合俊英

内科 105(2), 335〜337, 2010/2
10

A study on the deterioration of mortar due to sulfuric acid attack in sewerage [in Japanese]

高野修壮 , 米倉亜州夫 , 伊藤秀敏 [他]

Bulletin of Hiroshima Institute of Technology. Research volume 44, 85〜90, 2010/2
11

Relative loss of vitamin K after hip fracture surgery [in Japanese]

山口徹 , 小倉洋二 , 辻秀一郎 [他]

Clinical orthopaedic surgery 45(2), 151〜156, 2010/2
12

Endocrine associated disease (body weight loss, diabetes mellitus, and osteoporosis) [in Japanese]

小川惠美子

Respiration and circulation 58(2), 151〜157, 2010/2

Ichushi
13

Surface excitations in surface electron spectroscopies studied by reflection electron energy-loss spectroscopy and elastic peak electron spectroscopy (A special issue on advances in surface chemical analysis: from fundamentals to standardization)

Nagatomi Takaharu , Tanuma Shigeo

Analytical Sciences 26(2), (213) 165〜176, 2010/2
14

Clinical features and management of five patients with supratentorial subependymoma

Fujisawa Hironori , Hasegawa Mitsuhiro , Ueno Megumi , 藤沢弘範

… Of the three symptomatic patients, one presented with sudden loss of consciousness despite having only a small tumor, while in contrast, another patient showed only gradual memory disturbance despite having a very large tumor (90 mm diameter). …

Journal of Clinical Neuroscience 17(2), 201-204, 2010-02

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15

根治的前立腺全摘除術後の吻合部狭窄と縫合糸の関連性の検討 [in Japanese]

佐野剛視 , 井口亮 , 添田朝樹 , 金丸聰淳 , 伊藤哲之 , Sano Takeshi , Iguchi Ryo , Asaki Soeda , Kanamaru Sojun , Ito Noriyuki

… In group B, operation time was longer, blood loss was less and tumor stage was lower. …

泌尿器科紀要 56(2), 95-98, 2010-02

IR
16

The Log-effect for 2 by 2 hyperbolic systems

Kinoshita Tamotu , Reissig Michael , 木下保

… The precise loss of regularity is of interest. …

Journal of differential equations 248(3), 470-500, 2010-02

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17

英米法における電子情報取引と経済的損失の賠償について(一)

川和功子 , カワワノリコ , Kawawa Noriko

… Compensation for economic loss in electronic information transactions …

同志社法學 61(6), 39-63, 2010-01-31

IR
18

Vibration Damping Characterisitics of Thin Plate Structures by Damping Paint [in Japanese]

Yasunori WAKASAWA , Yuichi MORIKAWA , Masatoshi HASHIMOTO

Journal of Toyota College of Technology 42, 13-18, 20100120
19

Automotive: Design of superconducting motor [in Japanese]

馬場猛 , 尾山仁 , 有吉剛 [他]

SEI technical review (176), 45〜50, 2010/1
20

History of power capacitors: the progress in size and loss reduction [in Japanese]

村岡隆

SEI technical review (176), 31〜39, 2010/1

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