Search Results:　 1-20 of 20

JUNG Mankil , LEE Hyun Chul , AHN Chul Woo , PARK Whuijung , CHOI Sunhee , KIM Hanjo , CHO Donghak , LEE Geun Taek , LI Hai-Ri

… We developed an effective isolation method of magnesium lithospermate B from Salviae miltiorrhizae Radix and found for the first time that magnesium lithospermate B shows strong in vitro inhibition (IC_<50>=0.04 μM) of aldose reductase (AR), 2.5 times than that of clinically used epalrestat (IC_<50>=0.1 μM) and accumulation of fibronectin dose dependantly. …

Chemical & pharmaceutical bulletin 50(8), 1135-1136, 2002-08-01

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TEZUKA Yasuhiro , KASIMU Rena , LI Jian Xin , BASNET Purusotam , TANAKA Ken , NAMBA Tsuneo , KADOTA Shigetoshi

… miltiorhiza, which contains "tanshinones" as diterpenes and magnesium lithospermate B as the main caffeic acid derivative. …

Chemical & pharmaceutical bulletin 46(1), 107-112, 1998-01-15

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Baek B. S. , Paik K. J. , Shim K. H. , Chung H. Y. , Yokozawa T. , Oura H.

The general meeting of Medical and Pharmaceutical Society for Wakan-yaku abstracts 13, 124, 1996-08-01

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YOKOZAWA TAKAKO , CHUNG HAE YOUNG , OURA HIKOKICHI , NONAKA GEN-ICHIRO , NISHIOKA ITSUO

… The antihypertensive effect of magnesium lithospermate B isolated from Salviae Miltiorrhizae Radix was evaluated using spontaneously hypertensive rats (SHR). … Oral administration of magnesium lithospermate B lowered the systolic, mean and diastolic blood pressures in SHR, in comparison with the progressive hypertension observed in untreated control animals. …

Natural medicines 49(2), 164-167, 1995-06-20

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周 家俊 , 横澤 隆子 , 柏木 寛 , 服部 征雄 , 大浦 彦吉

The general meeting of Medical and Pharmaceutical Society for Wakan-yaku abstracts 11, 71, 1994-08-01

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横澤 隆子

The general meeting of Medical and Pharmaceutical Society for Wakan-yaku abstracts 11, 7, 1994-08-01

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YOKOZAWA Takako , CHUNG Hae Young , LEE Tae Woong , OURA Hikokichi , NONAKA Gen-ichiro , NISHIOKA Itsuo

… The renal responses of magnesium lithospermate B were investigated in the presence or absence of pretreatment with the converting enzyme (kininase II) inhibitor, captopril, in rats with adenine-induced renal failure. …

Chemical & pharmaceutical bulletin 39(3), 732-736, 1991-03-25

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YOKOZAWA Takako , CHUNG Hae Young , LEE Tae Woong , OURA Hikokichi , TANAKA Takashi , NONAKA Gen-ichiro , NISHIOKA Itsuo

… The effect of magnesium lithospermate B isolated from Salviae miltiorrhizae Radix on excretion of urinary arachidonate metabolites was examined in both normal rats and those given adenine. … Rats administered magnesium lithospermate B showed an increase of urinary PGE_2 excretion at the 6th and 12th days. …

Chemical & pharmaceutical bulletin 37(10), 2766-2769, 1989-10-25

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TANAKA Takashi , MORIMOTO Satoshi , NONAKA Gen-ichiro , NISHIOKA Itsuo , YOKOZAWA Takako , CHUNG Hae Young , OURA Hikokichi

… The active components which exhibit the improving effect on uremic symptoms have been isolated from Salviae miltriorrhizae Radix and characterized as magnesium lithospermate (1) and ammonium-potassium lithospermate (2). …

Chemical & pharmaceutical bulletin 37(2), 340-344, 1989-02-25

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