Search Results:　 1-20 of 297

  • 1

    A Case Report of Epithelioid Malignant Pleural Mesothelioma Showing a Complete Response Treated with Non-pemetrexed Chemotherapy  [in Japanese]

    Tamura Kunihiro , Ohtsuki Tai-ichiro , Shibata Eisuke , Kanemura Shingo , Yasumitsu Akihiro , Tsukamoto Yoshitane , Komuta Kiyoshi , Tabata Chiharu , Fukuoka Kazuya , Nakano Takashi

    背景.悪性胸膜中皮腫は治療に抵抗する予後不良の腫瘍である.非切除例の生存期間は10〜12か月であり,化学療法で完全奏効(CR)が得られることは稀である.症例. 74歳女性,主訴は右胸部痛,アスベスト曝露歴がある.胸部圧迫感を自覚し近医を受診,右胸水貯留の指摘を受け来院した.胸水細胞診では癌胎児性抗原(CEA)染色陰性,カルレチニン染色陽性の悪性細胞が認められ,悪性胸膜中皮腫が強く疑われた.局所麻酔 …

    The journal of the Japan Society for Bronchology 34(3), 228-233, 2012-05-25

    CiNii Fulltext PDF - Open Access  Ichushi Web References (14)

  • 2

    RENAL EPITHELIOID ANGIOMYOLIPOMA WITH MALIGNANT BEHAVIOR  [in Japanese]

    石川 哲生 , 伊藤 文夫 , 金光 泉 他

    … Computed tomography showed bilateral renal masses with minimal fat tissue that were unlike classical angiomyolipoma (AML), as well as enlargement of the paraaortic lymph nodes, pleural effusion, and ascites, similar to other advanced malignant neoplasms such as renal cell carcinoma and renal sarcoma. …

    泌尿器科紀要 58(1), 21-24, 2012-01-00

    IR Ichushi Web

  • 3

    A case of advanced lung cancer treated by surgery followed by adjuvant combination therapy of gefitinib and interleukin-2 lymphokine-activated killer cell immunotherapy

    Ayabe Takanori , Shimizu Tetsuya , Tomita Masaki , Kushima Yoshiaki , Onitsuka Toshio

    … However, the CT scanning revealed that several small nodules on pleural surface might suspect a pleural dissemination, that is, IV-staged advanced lung cancer. … After thoracotomy, the small pleural nodules were intraoperatively diagnosed with pleural dissemination by pathological examination. …

    Annals of Cancer Research and Therapy 20(1), 11-16, 2012

    J-STAGE CrossRef

  • 4

    Response to Low-dose Bortezomib in Plasma Cell Leukemia Patients with Malignant Pleural Effusion and Ascites: A Case Report and a Review of the Literature

    Sekiguchi Yasunobu , Shirane Syuichi , Imai Hidenori , Sugimoto Keiji , Wakabayashi Mutsumi , Sawada Tomonori , Chigira Noriko , Ichikawa Kunimoto , Komatsu Norio , Noguchi Masaaki

    … Pleural effusion or ascites complicating plasmacytoma is rare and has a poor prognosis. … After MP he was diagnosed to have pleural effusion and ascites as a complication of the plasmacytoma. … Low-dose bortezomib caused disappearance of the malignant effusion. … The malignant effusions recurred after the end of the second course of bortezomib. …

    Internal Medicine 51(11), 1393-1398, 2012

    J-STAGE CrossRef

  • 5

    Intrathoracic Administration of OK-432 Elevates the Serum Procalcitonin Levels

    Ogasawara Takashi , Umezawa Hiroki , Kato Shinpei , Yano Toshiaki , Kasamatsu Norio , Hashizume Ikko

    … Objective The intrathoracic administration of OK-432, a lyophilized preparation of the heat- and penicillin-treated Su-strain of type 3, group A Streptococcus pyogenes, is performed in Japan for pleurodesis of malignant pleural effusion or pneumothorax. … Methods We performed a prospective study of 12 patients with refractory pleural effusion or pneumothorax who required pleurodesis using OK-432 between August 2011 and February 2012. …

    Internal Medicine 51(19), 2727-2731, 2012

    J-STAGE CrossRef

  • 6

    Morphological Characteristics of 9p21 Homozygous Deletion-Positive Malignant Pleural Mesothelioma Cells Detected by FISH  [in Japanese]

    Nabeshima Kazuki , Matsumoto Shinji , Hamasaki Makoto , Ohgami Akiko , Kamei Toshiaki , Iwasaki Akinori

    背景と目的．悪性胸膜中皮腫（MPM）患者の多くは胸水にて発症するので，胸水細胞診による診断は重要である．しかし，MPMに対する免疫細胞化学的マーカーの欠如と細胞診上の確固たる診断基準が未確立であるため，MPMと反応性中皮細胞（RMC）の鑑別を困難にしている．さらに胸水中にMPM細胞もRMCもともに存在することがその鑑別を一層困難にしている．染色体の9p21領域に存在するCDKN2A/p16遺伝子の …

    Haigan 52(2), 201-208, 2012

    J-STAGE Ichushi Web CrossRef

  • 7

    Clues to the Early Diagnosis of Malignant Pleural Mesothelioma -Evaluation of Cytological Features at the Molecular Level-  [in Japanese]

    Tsujimura Tohru , Sato Ayuko , Torii Ikuko , Kamei Toshiaki , Hasegawa Seiki , Nakano Takashi

    目的．悪性胸膜中皮腫（MPM）の胸水細胞診では，細胞質に重厚感がみられ，細胞封入像や多核細胞が高頻度に出現する．細胞質の重厚感には中間径フィラメントが関与し，細胞封入や多核細胞の形成には細胞融合を促す細胞接着分子が重要な役割を果たしている可能性がある．そこで，我々は，MPMと反応性中皮（RM）における中間径フィラメント及び細胞接着分子の発現を比較した．方法．MPMとRMの遺伝子発現プロファイルをA …

    Haigan 52(2), 196-200, 2012

    J-STAGE Ichushi Web CrossRef

  • 8

    Comparisons of the New TNM Staging System for Lung Cancer (UICC-7) and Revisions of the General Rules for the Clinical and Pathological Classification of Lung Cancer of the Japan Lung Cancer Society  [in Japanese]

    Mitsudomi Tetsuya , Fukui Takayuki

    目的．日本肺癌学会肺癌取扱い規約委員会は，UICCのTNM分類第7版改訂に対応して取扱い規約の見直しを行い，2010年3月に確定版を完成したが，その経緯の説明と内容を解説すること．方法．UICC TNM分類第6版，第7版，肺癌取扱い規約第7版の異同を主に検討した．結果．主な変更点は，1）T因子の腫瘍径による細分化，2）悪性胸水をT4からM1a，同側他葉腫瘤をM1からT4へ変更，3）胸膜浸潤分類をP …

    Haigan 52(1), 80-84, 2012

    J-STAGE Ichushi Web CrossRef

  • 9

    Identification of Pleural Effusion with Low Levels of Adenosine Deaminase but Without Signs of Acute Inflammation or Pleural Thickening to Diagnose Early Malignant Pleural Mesothelioma  [in Japanese]

    Moriyama Satoru , Tanahashi Masayuki , Suzuki Eriko , Haneda Hiroshi , Yoshii Naoko , Yamada Takeshi , Sasaki Hidefumi , Yano Motoki , Fujii Yoshitaka , Niwa Hiroshi

    … 目的．悪性胸膜中皮腫（malignant pleural mesothelioma：MPM）が疑われる，急性炎症所見がないアデノシンデアミナーゼ（adenosine deaminase：ADA）低値原因不明胸水および胸膜肥厚症例の臨床所見および診断方法についてretrospectiveに検討した．対象と方法．滲出性，リンパ球優位，抗酸菌および一般細菌検査陰性，ADA低値の原因不明胸水および胸水を伴う，伴わないにかかわらず，胸膜肥厚を認めた40例を対象 …

    Haigan 52(1), 10-16, 2012

    J-STAGE Ichushi Web CrossRef

  • 10

    A case of endometrial intraepithelial carcinoma (EIC) detected by cervical cancer screening  [in Japanese]

    AKASHI Kyoko , UEDA Masatsugu , AKISE Hikari , SATO Naomi , IZUMA Shinji , TANAKA Ichiro , OKAMOTO Yoshiaki , NODA Sadamu , SAKAI Masahiro , MAEDA Takayoshi

    子宮頸部細胞診を機に発見し，早期に加療しえたendometrial intraepithelial carcinoma（以下，EIC）の症例を報告する．症例は子宮頸部細胞診にてクラスIV，ベセスダシステムにてAGC-favor neoplasticと診断された60歳女性である．経腟超音波上，5cm大の子宮筋腫の他は婦人科的に特記すべき所見を認めず，子宮内膜も萎縮様であった．再検した子宮頸部および子 …

    ADVANCES IN OBSTETRICS AND GYNECOLOGY 64(3), 319-325, 2012

    J-STAGE Ichushi Web

  • 11

    A Case of Postoperative Recurrence of Gastric Cancer with Diffuse Metastasis Around the Entire Subpleural Layer  [in Japanese]

    Amano Yosuke , Kage Hidenori , Nakajima Jun , Nagase Takahide

    背景.悪性胸水はしばしば悪性腫瘍発見の契機になるが,悪性胸水の診断は時に胸水細胞診や経皮的胸膜生検で得られず難渋することがある.症例.76歳男性.3年前に胃癌stage IBに対する幽門側胃切除の既往があった.微熱を主訴に近医受診し,右胸水を指摘され,当科入院となった.胸腔穿刺を施行し,ADA正常,CEA高値を示す滲出性胸水が得られたが,細胞診はclass 1であった.胸部CTでは右肺の臓側胸膜お …

    The journal of the Japan Society for Bronchology 33(6), 464-468, 2011-11-25

    CiNii Fulltext PDF - Open Access  Ichushi Web References (10)

  • 12

    A Case of Small Cell Mesothelioma with Rapid Growth  [in Japanese]

    Ishikawa Yumiko , Kobayashi Kazuyuki , Funada Yasuhiro , Yamamoto Masatsugu , Hori Suya , Shinke Haruko , Hatakeyama Yukihisa , Sakashita Akihiro , Kotani Yoshikazu , Nishimura Yoshihiro , Obayashi Chiho

    背景.小細胞型中皮腫は悪性胸膜中皮腫の中でも稀な組織型でありその報告は極めて少ない.症例.74歳男性.肝細胞癌治療中の3年前から原因不明の右胸水貯留を指摘されていた.2006年3月胸部CT,局所麻酔下胸腔鏡胸膜生検で精査するも確定診断に至らなかった.同年7月より背部痛と呼吸困難が出現し,再検した胸部CTにて以前は認めなかった胸腔を占拠する巨大腫瘤を認めた.その後,急速に呼吸不全となり同年8月に永眠 …

    The journal of the Japan Society for Bronchology 33(6), 435-442, 2011-11-25

    CiNii Fulltext PDF - Open Access  Ichushi Web References (14)

  • 13

    Is Adenosine Deaminase in Pleural Fluid a Useful Marker for Differentiating Tuberculosis from Lung Cancer or Mesothelioma in Japan, a Country with Intermediate Incidence of Tuberculosis?

    Ogata Yoshiko , Aoe Keisuke , Hiraki Akio , Murakami Kazuo , Kishino Daizo , Chikamori Kenichi , Maeda Tadashi , Ueoka Hiroshi , Kiura Katsuyuki , Tanimoto Mitsune

    … The objective of this study was to evaluate the utility of the determination of adenosine deaminase (ADA) level in pleural fluid for the differential diagnosis between tuberculous pleural effusion (TPE) and malignant pleural effusion (MPE) in Japan, a country with intermediate incidence of tuberculosis (TB). …

    Acta Medica Okayama 65(4), 259-263, 2011-08-00

    IR

  • 14

    Suitable device for thoracoscopic talc poudrage in malignant pleural effusion

    BILLE Andrea , BORASIO Piero , GISABELLA Mara , ERRICO Luca , GATHERER Robert , ARDISSONE Francesco

    General thoracic and cardiovascular surgery 59(7), 522-524, 2011-07-10

    Ichushi Web References (8)

  • 15

    CPC case: Malignant tumor cells of unknown origin found in the pleural effusion from a male patient in his 60's during medical treatment for chronic pyothorax  [in Japanese]

    田村 元 , 安孫子 正美 , 湯田 淳一朗 他

    山形県立病院医学雑誌 45(2), 191-205, 2011-07-00

    Ichushi Web

  • 16

    Exploratory Study on the Detection of Markers for Diagnosing Early-Stage Malignant Mesothelioma  [in Japanese]

    FUKUOKA Kazuya , TANAKA Fumihiro , TSUJIMURA Tohru , HASHIMOTO-TAMAOKI Tomoko , HASEGAWA Seiki , NAKANO Takashi

    … Malignant mesothelioma (MM) is a highly aggressive, incurable neoplasm associated with asbestos exposure. … SMRP levels in pleural effusion were elevated not only in advanced-stage malignant pleural mesothelioma (MPM), but also in early-stage disease. … SMRP in pleural effusion can be an MPM-specific biomarker with greater sensitivity than in serum, especially for the early stage of the disease. …

    Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 66(3), 553-557, 2011-05-15

    J-STAGE Ichushi Web CrossRef References (11) Cited by (1)

  • 17

    Intracardiac Metastasis of Esophageal Squamous Cell Carcinoma : Report of a Case

    TAYAMA Keiichiro , ENOMOTO Naofumi , KOHNO Michitaka , TOBINAGA Satoru , OTSUKA Hiroyuki , KOSUGA Ken-ichi

    … After admittance to Munakata Suikokai General Hospital, Fukuoka, Japan, echocardiography showed extensive pleural and pericardial effusion and a mass, 4 by 2 cm, with a solid echo pattern in the right ventricular cavity. … The working diagnosis was primary malignant cardiac tumor of unknown origin with multiple metastases. …

    Annals of Thoracic and Cardiovascular Surgery 17(2), 166-169, 2011-04-01

    J-STAGE Ichushi Web CrossRef References (7)

  • 18

    A case of Wilms tumor with pleural effusion before treatment  [in Japanese]

    Daifu Tomoo , Watanabe Kenichiro , Kato Itaru , Uryu Kumiko , Tokumasu Mayu , Umeda Katsutsugu , Matubara Hiroshi , Adachi Souichi , Okamoto Shinya , Uemoto Shinji , Nakahata Tatsutoshi

    治療前に胸水を伴った右腎臓原発Wilms腫瘍の3歳女児,胸水細胞診が陰性であったため肺照射は行わず,JWiTS-2(Japan Wilms Tumor Study-2)のプロトコールに従って治療を行ったところ,現在治療終了後3年,無再発生存を得ている.治療前に胸水を伴うWilms腫瘍の治療方針について考察した.

    Pediatric oncology 48(1), 28-31, 2011-02-25

    CiNii Fulltext PDF - Open Access  Ichushi Web References (8)

  • 19

    Pleuroperitoneal Shunt for Chylothorax and Chylopericardium in Lung Cancer : A Case Report

    SHIMMYO Takuo , MORITA Katsuhiko , MINESHITA Masamichi , TAGAYA Rie , ANDO Koji , MOCHIZUKI Atsushi , KURIMOTO Noriaki , MIYAZAWA Teruomi , OSADA Hiroaki , NAKAMURA Haruhiko

    … A pleuroperitoneal shunt was inserted into the right pleural cavity from the fifth intercostal space, and a peritoneal catheter was placed in the abdominal cavity. … This case indicates that a pleuroperitoneal shunt can be used for lung cancer-related chylothorax, as well as for malignant pleural effusion. …

    Annals of Thoracic and Cardiovascular Surgery 17(1), 63-66, 2011-02-01

    J-STAGE Ichushi Web CrossRef References (9)

  • 20

    A Case of Primary Lung Cancer with Malignant Pleural Effusion but Without Visceral Pleural Invasion or Dissemination  [in Japanese]

    Arai Hiromasa , Inui Kenji , Nishii Teppei , Chiba Sawako , Oshiro Hisashi , Masuda Munetaka

    背景．稀ではあるが，臓側胸膜浸潤のない肺癌症例でも，術中に存在する胸水中に癌細胞が証明されることがある．臨床病理学的にも病期診断に極めて重要な所見であり，癌進展の自然史としても興味深い病態であるが，その機序は明らかでない．症例．血痰を契機に発見された左上葉原発，肺腺癌の68歳・男性．臨床病期はstage IAであった．術中所見では，少量の漿液性胸水を認めた他は，臓側胸膜面の変化や播種巣などはなく， …

    Haigan 51(7), 793-797, 2011

    J-STAGE Ichushi Web CrossRef

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