CiNii Articles - nucleic acid

1

A case of post-transfusion hepatitis by an occult HBV carrier [in Japanese]

山下信行 , 谷本博徳 , 野村秀幸

肝臓 54(1), 60-66, 2013-01-00
2

Pretreatment of Hepatocyte Growth Factor Gene Transfer Mediated by Octaarginine Peptide-Modified Nanoparticles Ameliorates LPS/D-Galactosamine-Induced Hepatitis

Hayashi Yasuhiro , Mizuno Ryoichi , Ikramy Khalil A. , Akita Hidetaka , Harashima Hideyoshi

We previously reported that an octaarginine- and pH-sensitive fusogenic peptide-modified multifunctional envelope-type nano device (R8-GALA-MEND) produces a high level of gene expression in the liver. …

Nucleic Acid Therapeutics 22(5), 360-363, 2012-10-02

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3

Patentability of Use of Nucleic Acid for Pharmaceuticals and Diagnostics [in Japanese]

医薬・バイオテクノロジー委員会第1小委員会

知財管理 = Intellectual property management 62(10), 1401-1419, 2012-10-00
4

Development of Cell-Selective Nucleic Acid Transferring System Using Ultrasound-Responsive and Mannose-Modified Liposomes [in Japanese]

UN Keita

薬剤学 = The archives of practical pharmacy 72(4), 226-231, 2012-07-01

Ichushi Web References (5)
5

Detection of microbe from cosmetic products using Rapid and Simple nucleic-acid amplification test kit based on Loop-mediated Isothermal Amplification (LAMP) [in Japanese]

保坂憲光 , 吉野学 , 横田江利子他

Fragrance journal 40(7), 69-73, 2012-07-00
6

Development of Decoy Type Nucleic Acid Medicines [in Japanese]

森下竜一

Bio industry 29(7), 54-58, 2012-07-00
7

Nucleic Acid Delivery [in Japanese]

望月慎一 , 櫻井和朗

Bio industry 29(7), 24-29, 2012-07-00
8

2'-O,4'-C-ethylene bridged nucleic acid modification enhances pyrimidine motif triplex-forming ability under physiological condition

Torigoe Hidetaka , Sato Norihiro , Nagasawa Nobuyuki

Journal of Biochemistry 152(1), 17-26, 2012-07-00
9

The Peptide Nucleic Acid-Locked Nucleic Acid Polymerase Chain Reaction Clamp-Based Test for Epidermal Growth Factor Receptor Mutations in Bronchoscopic Cytological Specimens of Non-Small Cell Lung Cancer

Yamada Noriyuki , Oizumi Satoshi , Asahina Hajime , Shinagawa Naofumi , Kikuchi Eiki , Kikuchi Junko , Sakakibara-Konishi Jun , Tanaka Tomoaki , Kobayashi Kunihiko , Hagiwara Koichi , Nishimura Masaharu

… Methods: We retrospectively examined the efficacy of the peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp (PNA-LNA PCR clamp) method for detecting EGFR mutations in 122 bronchoscopic cytological specimens from NSCLC patients. …

Oncology 82(6), 341-346, 2012-07-00

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10

HELICAL STRUCTURES OF HETEROCHIRAL DNA DIMERS AND COMPARISON WITH RNA DIMERS [in Japanese]

Urata Hidehito , Hirata Yoshihiro , Toji Takako , Ochiai Ikumi , Akagi Masao

自己複製分子のホモキラリティーの確立とRNAワールド仮説との関連を考察する一環として,2'-deoxyadenylyl-(3'-5')-2'-deoxyadenosine[d(ApA)]の4種の光学異性体[D-d(ApA),d(ADpAL),d(ALpAD),L-d(ApA)]を合成し,それらの右巻きらせん形成能について検討を行った.円二色性(CD)スペクトルからD-d(ApA)とd(ALpAD) …

Viva origino 39(1-4), 49-54, 2012-06-20

CiNii Fulltext PDF - Open Access
11

Perspective on Nucleic Acid Medicines based on DDS [in Japanese]

梶本和昭 , 兵藤守 , 小暮健太朗他

ファインケミカル : 調査・資料・報道・抄録 41(4), 31-36, 2012-04-00
12

Regulation of erythropoiesis by microbial nucleic acid [in Japanese]

GUO Yong-Mei , 澤田賢一

臨床血液 53(3), 295-302, 2012-03-30

Ichushi Web References (80)
13

6 Stability of nucleic acid bases against soft X-rays and heavy ion particles(General Contnbutions,The 37^<th> Annual Meeting of the SSOEL-Japan) [in Japanese]

Okabe T. , Kawamoto Y. , Eto M. , Kaneko T. , Obayashi Y. , Takahashi J. , Kanda K. , Yoshida S. , Kobayashi K.

Viva origino 40(Supplement), 13, 2012-03-01

CiNii Fulltext PDF - Open Access
14

Synthesis of Novel Oligocationic Peptides Which Bind to A-Type Nucleic Acid Duplexes

MAEDA Yusuke , IWATA Rintaro , WADA Takeshi

Peptide science : proceedings of the ... Japanese Peptide Symposium 2011, 231-232, 2012-03-01

References (1)
15

Theoretical Conformation Analysis of Amino-Acid Residue Designed as Analogue of Peptide Nucleic Acids

OKA Masahito , INAI Koji

Peptide science : proceedings of the ... Japanese Peptide Symposium 2011, 197-200, 2012-03-01

References (4)
16

Application of electrospray ionization ion trap/time-of-flight mass spectrometry for chemically-synthesized small RNAs(METHODS)

Izumi Yoshihiro , Takimura Shin , Yamaguchi Shinichi , Iida Junko , Bamba Takeshi , Fukusaki Eiichiro

… Further, the detailed structural analysis of 3'-terminal modified nucleic acid in intact methylated miRNA was carried out using the MS^3 capability of the hybrid IT/TOFMS. …

Journal of bioscience and bioengineering 113(3), 412-419, 2012-03-00

CiNii Fulltext PDF - Paid Ichushi Web References (48)
17

Aspiration Biopsy-Nucleic Acid Diagnosis for Widely Used Preparative Testing [in Japanese]

TAKANO Toru

臨床病理 60(2), 132-138, 2012-02-25

Ichushi Web References (11)
18

Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq

Someya Tatsuhiko , Baba Seiki , Fujimoto Mai , Kawai Gota , Kumasaka Takashi , Nakamura Kouji , 中村幸治

… Mutational and structural studies revealed that the RNA fragment binds to the distal site, one of the two binding sites on Hfq, and identified amino acid residues that are critical for sequence-specific interactions between BsHfq and (AG)3A. …

Nucleic acids research 40(4), 1856-1867, 2012-02-00

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19

Study on improvement effect of RNA virus detection using the metal-coated hollow fiber membrane with reverse transcription loop-mediated isothermal amplification from a human plasma sample [in Japanese]

ENDOU Taichi , SUGAWARA Toshitsugu , ARISAWA Junji , KIMURA Kazuyuki , IGARASHI Osamu

我々は,微量なウイルスに対しても検出を可能とした遺伝子増幅法を提案した.それは,日本赤十字社が輸血用血液の安全性を確保するため血漿試料を対象に行っている核酸増幅検(NAT)への応用を目的としている.具体的には,NAT過程の前段階にウイルスの捕捉・濃縮・分離が一体化で実施できる導電性中空糸膜を付加した手法を開発し,RT-LAMP法と併用した迅速で高感度な検査法をこれまで報告してきた.本法では臨床応用 …

IEICE technical report. ME and bio cybernetics 111(423), 65-70, 2012-01-20

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20

Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer.

Kurosaki Tomoaki , Higuchi Norihide , Kawakami Shigeru , Higuchi Yuriko , Nakamura Tadahiro , Kitahara Takashi , Hashida Mitsuru , Sasaki Hitoshi

We have developed a novel vector constructed with pDNA, polyethylenimine (PEI), and mucin 1 (MUC1) aptamer for tumor-targeted gene delivery. The MUC1 aptamer and non-specific aptamer were employed to …

Gene 491(2), 205-209, 2012-01-10

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