CiNii Articles

1

Frequent silencing of tumor-suppressive miR-34b/c by aberrant methylation in malignant pleural mesothelioma [in Japanese]

久保孝文 , 豊岡伸一 , 三好新一郎

岡山医学会雑誌 124(3), 203-206, 2012-12-00

IR CrossRef
2

Case Report : A case of multiple myeloma which cells gained multiple gene and chromosome aberrations and changed their morphology to plasmablastoid and lymphoblastoid during less than two years course [in Japanese]

田近賢二 , 奥山奈美子 , 五味聖二

日本内科学会雑誌 101(11), 3236-3238, 2012-11-10
3

Regulation of Mitochondrial Function by Deacetylase in Early Embryos [in Japanese]

河村悠美子 , 栗原裕基

Journal of mammalian ova research 29(4), 161-169, 2012-10-00

Ichushi Web
4

E-cadherin/p53 double conditional knockout mouse model of diffuse-type gastric cancer [in Japanese]

島田周 , 秋山好光 , 湯浅保仁

日本臨床 70(10), 1660-1665, 2012-10-00

Ichushi Web
5

ラット甲状腺濾胞上皮のDNA損傷応答と放射線誘導オートファジーに対する年齢の影響 [in Japanese]

松山睦美 , 七條和子[他]

… る2).昨年の本研究会でわれわれは,8Gy X線照射後24時間までの未熟4週齢と成熟7週齢ラット甲状腺で,未熟甲状腺濾胞上皮ではKi67陽性細胞の発現減少や細胞質空胞変性を認め,両群ともアポト-シスは観察されず,Ser15リン酸化p53の発現は増加するが,p21, cleaved caspase-3の発現に変化のないこと,4週齢ラット甲状腺の電子顕微鏡像でオ-トファジ-像が照射後6時間に観察され,オ-トファジ-の分子指標であるLC3-IIの発現増加を報告した3). …

Nagasaki Igakkai zasshi = Nagasaki medical journal 87(特集), 269-272, 2012-09-25
6

Overexpression of p53 protein in human tumors

INOUE Keiji , KURABAYASHI Atsushi , SHUIN Taro , OHTSUKI Yuji , FURIHATA Mutsuo

Medical molecular morphology : official journal of the Japanese Society for Clinical Molecular Morphology 45(3), 115-123, 2012-09-01

References (114)
7

Recent research advances in 5q- syndrome [in Japanese]

松岡亮仁

血液内科 65(3), 316-322, 2012-09-00

Ichushi Web
8

A mechanism of insulin resistance associated with heart failure [in Japanese]

須田将吉 , 吉田陽子 , 清水逸平他

内分泌・糖尿病・代謝内科 35(3), 242-247, 2012-09-00

Ichushi Web
9

Crosstalk between microRNA processing and signaling pathways in cancer [in Japanese]

鈴木洋 , 宮園浩平

細胞 44(10), 448-451, 2012-09-00

Ichushi Web
10

A case of extraskeletal chondroma : Ki-67, p53 staining was useful for the differentiation form chondrosarcoma [in Japanese]

茶谷彩華 , 畑康樹 , 宇月美和他

臨床皮膚科 66(10), 772-776, 2012-09-00

Ichushi Web
11

トップランナーに聞く : 最新医療に挑む若手研究者へのインタビュー(21)がん抑制遺伝子p53によるマイクロRNAプロセシング制御の解明 [in Japanese]

鈴木洋

最新医学 67(9), 2050-2055, 2012-09-00
12

Impact of serum biomarkers on esophageal squamous cell carcinoma

Shimada Hideaki , Yajima Satoshi , Oshima Yoko 他

Esophagus : official journal of the Japan Esophageal Society 9(3), 131-140, 2012-09-00
13

Regulatory effect of vitamin B_6 on gene expression in breast cancer cell lines [in Japanese]

Kanouchi Hiroaki , Oka Tatsuzo

… The induction of IGFBP by B_6 could be inhibited by a specific p53 inhibitor, pifithrin-α. … B_6 induced the accumulation of p53 protein itself, but not p53 mRNA. … We observed nuclear translocation of p53 protein in B_6-treated cells. … The growth inhibition of MCF-7 cells by 0.5 mM PL was rescued in the presence of p53 siRNA under the p53 knockdown conditions. …

Vitamins 86(8), 425-431, 2012-08-25

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14

Ki-67 Expression for Predicting Progression of Postoperative Residual Pituitary Adenomas : Correlations With Clinical Variables

MATSUYAMA Junko

… The World Health Organization classification of tumors of endocrine organs defines atypical pituitary adenomas as tumor with Ki-67 labeling index higher than 3%, excessive p53 immunoreactivity, and increased pleomorphism. …

Neurologia medico-chirurgica 52(8), 563-569, 2012-08-15

J-STAGE CrossRef References (34)
15

Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells

Song Ning , Boku Shuken , Nakagawa Shin , Kato Akiko , Toda Hiroyuki , Takamura Naoki , Omiya Yuki , Kitaichi Yuji , Inoue Takeshi , Koyama Tsukasa

… In addition, it has been shown that Li decreases the expression of p53, which plays a prominent role in apoptosis and regulates the expression of Bcl-2. … Therefore, p53 and Bcl-2 can be considered to mediate the common anti-apoptotic effects of Li, VPA, CBZ and LTG. …

Progress in Neuro-Psychopharmacology and Biological Psychiatry 38(2), 183-189, 2012-08-07

IR CrossRef
16

RXR antagonism induces G0/G1 cell cycle arrest and ameliorates obesity by up-regulating p53-p21[Cip] pathway in adipocytes [in Japanese]

中司敦子 , 和田淳 , 槇野博史

岡山医学会雑誌 124(2), 97-100, 2012-08-00

IR Ichushi Web CrossRef
17

Effects of epidermal growth factor on the proliferation and cell cycle regulation of cultured human amnion epithelial cells(CELL AND TISSUE ENGINEERING)

Fatimah Simat Siti , Tan Geok Chin , Chua Kien Hui , Tan Ay Eeng , Hayati Abdul Rahman

… EGF significantly decreased the mRNA expression of p21, pRb, p53 and GADD45 in cultured HAECs. …

Journal of bioscience and bioengineering 114(2), 220-227, 2012-08-00

CiNii Fulltext PDF - Paid
18

Approach to understanding the modes of action underlying ochratoxin A-induced renal carcinogenesis [in Japanese]

UMEMURA Takashi

… に係る遺伝子群の同定を試みた．皮質部では変化は認められず髄質外帯部においてのみ発現変動が認められた遺伝子として，DNA二重鎖切断修復，細胞周期促進，DNA損傷応答を介したG2/M arrest誘発，癌抑制遺伝子p53に関わる遺伝子群が抽出された．OTAの発がん標的部位においてDNA二重鎖切断修復関連遺伝子の変動が認められたことから，OTAが同部位に誘発する欠失変異はDNA二重鎖切断後の修復過程に生じている可能性が示 …

Mycotoxins 62(2), 143-148, 2012-07-31

J-STAGE CrossRef References (12)
19

A half-site of the p53-binding site on the keratin 14 promoter is specifically activated by p63

Cai Bi-He , Chao Chung-Faya , Lu Mei-Hua 他

Journal of Biochemistry 152(1), 99-110, 2012-07-00
20

Comparative micro-RNA expression profiling of brain tumor model dependent on p53/Tailless genes using adult brain-derived neural stem cells [in Japanese]

Shimozaki Kouji

… 野生型及び癌抑制遺伝子p53の欠損する成体脳由来神経幹細胞に核内受容体Tailless (TLX)を導入し、TLX遺伝子発現制御下におけるp53依存的癌幹細胞のモデル細胞を樹立後、miRNA発現比較解析を行った結果、p53欠損及びTLX遺伝子構成的発現依存的に、癌細胞の浸潤・転移と血管新生を促すmiRNAの関与が示唆された。 …

Nagasaki Igakkai zasshi = Nagasaki medical journal 87(2), 61-64, 2012-06-25

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