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Hypnotic Activities of Chamomile and Passiflora Extracts in Sleep-Disturbed Rats(Pharmacology)
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SHINOMIYA Kazuaki
,
INOUE Toshio
,
UTSU Yoshiaki
,
TOKUNAGA Shin
,
MASUOKA Takayoshi
,
OHMORI Asae
,
KAMEI Chiaki
… In the present study, we investigated hypnotic activities of chamomile and passiflora extracts using sleep-disturbed model rats. … A significant decrease in sleep latency was observed with chamomile extract at a dose of 300mg/kg, while passiflora extract showed no effects on sleep latency even at a dose of 3000mg/kg. … No significant effects were observed with chamomile and passiflora extracts on delta activity during non-REM sleep. …
Biological & pharmaceutical bulletin 28(5), 808-810, 20050501
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