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Time-lapse analysis of laser phase shift for noninvasive discrimination of human normal cells and malignant tumor cells(CELL AND TISSUE ENGINEERING)
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Takagi Mutsumi
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Shibaki Yuhei
… Time-lapse analysis of phase shift using phase-shifting laser microscopy (PLM) revealed that the laser phase shifts of primary normal human prostate epithelial cells (PRECs) and human prostatic carcinoma epithelial cell line (PC-3) cells during the mitotic phase were markedly higher than those in the interphase. … In conclusion, it was proposed that adherent PC-3 cancer cells could be noninvasively discriminated from normal adherent PRECs by the periodical measurement of phase shift using PLM during culture. …
Journal of bioscience and bioengineering 114(5), 556-559, 2012-11-00
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