CiNii Articles - proteasome

1

Kinetic asymmetry of subunit exchange of homooligomeric protein as revealed by deuteration-assisted small-angle neutron scattering.

Sugiyama Masaaki , Kurimoto Eiji , Yagi Hirokazu , Mori Kazuhiro , Fukunaga Toshiharu , Hirai Mitsuhiro , Zaccai Giuseppe , Kato Koichi

… We developed a novel, to our knowledge, technique for real-time monitoring of subunit exchange in homooligomeric proteins, using deuteration-assisted small-angle neutron scattering (SANS), and applied it to the tetradecamer of the proteasome α7 subunit. …

Biophysical journal 101(8), 2037-2042, 2011-10-19

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2

Effect of Endoplasmic Reticulum Stress on Laccase Production and the 26S Proteasome Activity in the White Rot Fungus Trametes versicolor

Staszczak Magdalena , Sajewicz Joannna , Ohga Shoji , 大賀祥治

… The ubiquitin?proteasome pathway is a major system for degrading intracellular proteins in eukaryotes. … In addition, the ubiquitin?proteasome system is responsible for endoplasmic reticulum?associated degradation. … proteasome?mediated pathway in Trametes versicolor is involved in the regulation of laccase, a main ligninolytic enzyme of this fungus, upon nutrient starvation as well as in response to cadmium exposure. …

Journal of the Faculty of Agriculture, Kyushu University 56(2), 205-211, 2011-09

IR
3

Ubiquitin Ligase Activity of Cul3-KLHL7 Protein Is Attenuated by Autosomal Dominant Retinitis Pigmentosa Causative Mutation

Kigoshi Yu , Tsuruta Fuminori , Chiba Tomoki , 木越悠 , 千葉智樹

… Substrate-specific protein degradation mediated by the ubiquitin proteasome system (UPS) is crucial for the proper function of the cell. … Proteins are specifically recognized and ubiquitinated by the ubiquitin ligases (E3s) and are then degraded by the proteasome. … Lys-48-linked but not Lys-63-linked polyubiquitin chain co-localized with KLHL7, which increased upon proteasome inhibition suggesting that KLHL7 mediates protein degradation via UPS. …

The journal of biological chemistry 286(38), 33613-33621, 2011-09

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4

22pJD-6 Protein Unfolding and Degradation by the Proteasome : the initiation step [in Japanese]

Inobe Tomonao

Meeting abstracts of the Physical Society of Japan 66(2-2), 318, 2011-08-24

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5

Ubiquitin chains in the Dsk2 UBL domain mediate Dsk2 stability and protein degradation in yeast

Sekiguchi Takeshi , Sasaki Toru , Funakoshi Minoru , Ishii Takashi , Saitoh Yoh-hei , Kaneko Shu-ichi , Kobayashi Hideki

… Ubiquitin-like (UBL)-ubiquitin-associated (UBA) proteins, including Dsk2 and Rad23, act as delivery factors that target polyubiquitinated substrates to the proteasome. … These results indicate that ubiquitination in the UBL domain of Dsk2 has in vivo functions in the ubiquitin-proteasome pathway in yeast. …

Biochemical and Biophysical Research Communications 411(3), 555-561, 2011-08-05

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6

PS-071-6 Proteasome inhibitor(Bortezomib)による抗体関連拒絶反応制御機構の証明(PS-071 ポスターセッション(71)移植,第111回日本外科学会定期学術集会) [in Japanese]

田澤宏文 , 伊禮俊充 , 五十嵐友香 , 田中友加 , 尾上隆司 , 井手健太郎 , 番匠谷将孝 , 田代裕尊 , 大段秀樹

Journal of Japan Surgical Society 112(臨時増刊号_1・2), 628, 2011-05-25

CiNii Fulltext PDF - Open Access Ichushi Web
7

A Tolerance Gene for Prenylated Flavonoid Encodes a 26S Proteasome Regulatory Subunit in Sophora flavescens

SHITAN Nobukazu , KAMIMOTO Yoshihisa , MINAMI Shota , KUBO Mizuki , ITO Kozue , MORIYASU Masataka , YAZAKI Kazufumi

… One cDNA, which conferred SFG tolerance, encoded a regulatory particle triple-A ATPase 2 (SfRPT2), a member of the 26S proteasome subunit. …

Bioscience, Biotechnology, and Biochemistry 75(5), 982-984, 2011-05-23

J-STAGE CrossRef References (12)
8

The C-terminus of MIP-T3 protein is required for ubiquitin-proteasome-mediated degradation in human cells.

Guo Chao-Wan , Liu Ge , Xiong Sheng , Ge Feng , Fuse Takayuki , Wang Yi-Fei , Kitazato Kaio

… Protein degradation is mediated by the ubiquitin-proteasome system, and the C-terminus is required for ubiquitination and proteasome-mediated degradation of MIP-T3 protein. …

FEBS Letters 585(9), 1350-1356, 2011-05-06

IR
9

Inhibition of proteasome activity leads to delay of the onset of ZGA gene expression in early mouse embryos [in Japanese]

SHIN Seung-Wook , TOKORO Mikiko , NISHIKAWA Satoshi , HATANAKA Yuki , LEE Hyang-Heun , SHIMIZU Natsumi , NISHIHARA Takuji , KATO Rie , AMANO Tomoko , MATSUMOTO Kazuya

Journal of mammalian ova research = 日本哺乳動物卵子学会誌 28(2), 80, 2011-04-01

References (4)
10

Platimun Compounds Involving New Anti-cancer Mechanism [in Japanese]

ODANI Akira

Biomedical research on trace elements 22(1), 22-26, 2011-04-01

Ichushi Web References (12)
11

Cadmium toxicity is caused by accumulation of p53 through the down-regulation of Ube2d family genes in vitro and in vivo

TOKUMOTO Maki , FUJIWARA Yasuyuki , SHIMADA Akinori , HASEGAWA Tatsuya , SEKO Yoshiyuki , NAGASE Hisamitsu , SATOH Masahiko

… To investigate the mechanisms of Cd-induced renal toxicity, we examined the effects of Cd on the ubiquitin-proteasome system, particularly the expression and function of Ube2d family members in the NRK-52E cells and mice. … Cd also dramatically increased p53 protein levels in the cells, without stimulation of p53 gene expression or inhibition of proteasome activity. …

The Journal of Toxicological Sciences 36(2), 191-200, 2011-04-01

J-STAGE CrossRef References (27)
12

Arabidopsis thaliana 26S Proteasome Subunits RPT2a and RPT5a Are Crucial for Zinc Deficiency-Tolerance

SAKAMOTO Takuya , KAMIYA Takehiro , SAKO Kaori , YAMAGUCHI Junji , YAMAGAMI Mutsumi , FUJIWARA Toru

… RPTs (regulatory particle triple-A-ATPase) are components of 26S proteasome. …

Bioscience, Biotechnology, and Biochemistry 75(3), 561-567, 2011-03-23

J-STAGE CrossRef References (27)
13

Synthetic studies of salinosporamide A through the intramolecular hydroamidation of alkynes

Kamisaki Haruhi , Kobayashi Yusuke , Kimachi Tetsutaro , Yasui Yoshizumi , Takemoto Yoshiji

… Rhodium-catalyzed intramolecular hydroamidation of alkynes was carried out to construct the synthetic intermediates of a proteasome inhibitor, salinosporamide A. …

Journal of Organometallic Chemistry 696(1), 42-45, 2011-01

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14

Recent advances and new perspectives in multiple myeloma treatments with novel agents [in Japanese]

花村一朗 , 飯田真介

血液内科 62(3), 338-350, 2011-03
15

Treatment for relapse/refractory multiple myeloma [in Japanese]

張高明

血液内科 62(3), 307-313, 2011-03
16

Drug development targeting the ubiquitin-proteasome system [in Japanese]

塚本佐知子 , 横沢英良

化学と生物 49(11), 745-754, 2011-11

Ichushi Web
17

β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency [in Japanese]

Costes Safia , Huang Chang-jiang , Gurlo Tatyana [他]

Diabetes 4(4), 39-41, 2011-09
18

RPT2a, a 26S proteasome AAA-ATPase, is directly involved in Arabidopsis CC-NBS-LRR protein uni-1D-induced signaling pathways

Chung KwiMi , Tasaka Masao

Plant and Cell Physiology 52(9), 1657-1664, 2011-09
19

Arabidopsis RPT2a encoding the 26S proteasome subunit is required for various aspects of root meristem maintenance, and regulates gametogenesis redundantly with its homolog, RPT2b

Ueda Minako , Matsui Keisuke , Ishiguro Sumie [他]

Plant and Cell Physiology 52(9), 1628-1640, 2011-09
20

Basic and clinical research on HIV-1 [in Japanese]

高折晃史

The Japanese journal of clinical hematology 52(10), 1705-1712, 2011-10

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