検索結果:　 5件中 1-5 を表示

  • 1

    Effect of Ethanol on Sleep-Awake State in Sleep-Disturbed Rats

    Obara Yoshihito , Tsutsui Ryuki , Ishida Takayuki , Kamei Chiaki

    … The present study was undertaken to investigate the effect of ethanol on the sleep-wake cycle in normal rats and sleep-disturbed rats. … In normal rats, no significant difference was observed by ethanol in sleep latency, total awake time and total non-rapid eye movement (NREM) sleep time, except for total REM sleep time. …

    Biological & Pharmaceutical Bulletin 33(5), 849-853, 2010

    J-STAGE 医中誌 CrossRef

  • 2

    Effect of Tandospirone on Sleep Latency in Rats Placed on a Grid Suspended Over Water

    UTSU Yoshiaki , SHINOMIYA Kazuaki , TOKUNAGA Shin , OHMORI Asae , KAMEI Chiaki

    … The present study was performed to examine the effect of tandospirone on sleep latency in a new insomnia animal model by placing rats on a grid suspended over water. … For investigating the mechanism of tandospirone, the effect of tandospirone on sleep latency was also studied using rats that were depleted with neuronal serotonin (5-HT) after p-chlorophenylalanine administration. …

    Journal of pharmacological sciences 105(1), 112-116, 2007-09-20

    J-STAGE 医中誌 CrossRef 参考文献18件 被引用文献3件

  • 3

    Effect of Valerian Extract Preparation (BIM) on the Sleep-Wake Cycle in Rats(Pharmacology)

    TOKUNAGA Shin , TAKEDA Yasuhiro , NIIMOTO Tsuyoshi , NISHIDA Norihisa , KUBO Toshihiro , OHNO Tohru , MATSUURA Youichi , KAWAHARA Yuzo , SHINOMIYA Kazuaki , KAMEI Chiaki

    … In the present study, we studied the effect of valerian extract preparation (BIM) containing valerian extract, golden root (Rhodiola rosea L.) extract and L-theanine (γ-glutamylethylamide) on the sleep-wake cycle using sleep-disturbed model rats in comparison with that of valerian extract. … A significant shortening in sleep latency was observed with valerian extract and the BIM at a dose of 1000mg/kg. …

    Biological & pharmaceutical bulletin 30(2), 363-366, 2007-02-01

    CiNii PDF - オープンアクセス  J-STAGE 医中誌 CrossRef 参考文献28件

  • 4

    Effects of valerian extract on the sleep-wake cycle in sleep-disturbed rats.

    Shinomiya Kazuaki , Fujimura Katsuyuki , Kim Yonsu , Kamei Chiaki

    … <p>The present study was performed to investigate the effects of valerian extract on the sleep-wake cycle using sleep-disturbed model rats. … A significant shortening in sleep latency was observed with valerian extract at doses of 1000 and 3000 mg/kg. …

    Acta Medica Okayama 59(3), 2005-06

    機関リポジトリ

  • 5

    Hypnotic Activities of Chamomile and Passiflora Extracts in Sleep-Disturbed Rats(Pharmacology)

    SHINOMIYA Kazuaki , INOUE Toshio , UTSU Yoshiaki , TOKUNAGA Shin , MASUOKA Takayoshi , OHMORI Asae , KAMEI Chiaki

    … In the present study, we investigated hypnotic activities of chamomile and passiflora extracts using sleep-disturbed model rats. … A significant decrease in sleep latency was observed with chamomile extract at a dose of 300mg/kg, while passiflora extract showed no effects on sleep latency even at a dose of 3000mg/kg. …

    Biological & pharmaceutical bulletin 28(5), 808-810, 2005-05-01

    CiNii PDF - オープンアクセス  J-STAGE 医中誌 CrossRef 参考文献19件