Search Results:　 1-20 of 1206

Abdel Rahman Doaa Ezzat

Chemical and pharmaceutical bulletin 61(2), 151-159, 2013-02-00

Mizuhara Tsukasa , Oishi Shinya , Ohno Hiroaki , Shimura Kazuya , Matsuoka Masao , Fujii Nobutaka

… 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine (PD 404182) is an antiretroviral agent with submicromolar inhibitory activity against human immunodeficiency virus-1 (HIV-1) and HIV-2 infection. … In the current study, the structure-activity relationships of accessory groups at the 3- and 9-positions of pyrimido[1,2-c][1,3]benzothiazin-6-imine were investigated for the development of more potent anti-HIV agents. …

Bioorganic & medicinal chemistry 20(21), 6434-6441, 2012-11-01

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TASHIRO Takuya

… In this review, structure-activity relationship studies of novel glycolipids which stimulate NKT cells efficiently are summarized. …

Bioscience, Biotechnology, and Biochemistry 76(6), 1055-1067, 2012-06-23

J-STAGE CrossRef References (161)

KAWASE Masaya , SAITO Tadashi , YASUNAGA Teruo , TAKAGI Tatsuya , FUKUDA Itsuko , ASHIDA Hitoshi

… This descriptor was applied to the Quantitative Structure-Activity Relationship (QSAR) study on the suppression activities of anthraquinones via transformation of the aryl hydrogen receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin. …

Food Science and Technology Research 18(2), 173-176, 2012-03-01

J-STAGE CrossRef References (9)

鈴木 孝弘 , 西田 健次 , 田辺 和俊

東洋大学紀要. 自然科学篇 (56), 65-73, 2012-03-00

ROSLIE Haslan , CHAN Kok Meng , RAJAB Nor Fadilah , VELU Saraswathi S. , KADIR Syed Abd. Illah Alyahya Syed Abd. , BUNYAMIN Irmaizatussyehdany , WEBER Jean-Frederic Faizal , THOMAS Noel F. , MAJEED Abu Bakar Abdul , MYATT Glenn , INAYAT-HUSSAIN Salmaan Hussain

… Additionally, a structure-activity relationship (SAR) study proposed a possible mechanism of action for compound 28. …

The Journal of Toxicological Sciences 37(1), 13-21, 2012-02-01

J-STAGE Ichushi Web CrossRef References (45)

Elkhateeb Ahmed , Tosa Yusuke , Matsuura Hideyuki 他

Journal of natural medicines 66(1), 233-240, 2012-00-00

Ichushi Web

Schott Jason Taylor , Mordaunt Charles Edward , Vargas Anthony Joseph , Leon Martin Antonio , Chen Kevin Hsinwen , Singh Mandeep , Satoh Mikiko , Cardenas Emilio Leal , Maitra Santanu , Patel Nilay Vinod , de Lijser Hubrecht Johan Peter

… We predict that further structure-activity-relationship (SAR) studies on chalcones with naphthalene or electron-rich groups near the carbonyl moiety will lead to the development of more potent PPARγ agonists. …

Chemical and Pharmaceutical Bulletin, 2012

J-STAGE CrossRef

YAMAZAKI Yoshimitsu , KAWANO Yasuhiro , NAGASHIMA Umpei

… The simple α,β-enone, 1-penten-3-one (6), showed the activities stronger than or comparable to those of the phenyl-conjugated α,β-enones including natural chalcones, suggesting that the α,β-enone structure in 6 is enough to induce the above inhibition. … Thus, the α,β-enone core singly suppresses the TNF-α and NO production in LPS-stimulated macrophages, but the conjugated hydroxyphenyl rings in chalcones are also important for their pharmacological activity. …

Journal of Computer Chemistry, Japan 11(3), 159-163, 2012

J-STAGE CrossRef

Bekki Kanae , Toriba Akira , Tang Ning , Kameda Takayuki , Takigami Hidetaka , Suzuki Go , Hayakawa Kazuichi

… In the biological activities caused by the above PAH derivatives, the structure-activity relationship was observed. …

YAKUGAKU ZASSHI 132(3), 325-329, 2012

J-STAGE Ichushi Web CrossRef