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Search Results:　 1-20 of 4585

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1

Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer.

Kurosaki Tomoaki , Higuchi Norihide , Kawakami Shigeru , Higuchi Yuriko , Nakamura Tadahiro , Kitahara Takashi , Hashida Mitsuru , Sasaki Hitoshi

We have developed a novel vector constructed with pDNA, polyethylenimine (PEI), and mucin 1 (MUC1) aptamer for tumor-targeted gene delivery. The MUC1 aptamer and non-specific aptamer were employed to …

Gene 491(2), 205-209, 2012-01-10

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2

Catch performance of coastal squid jigging boats using LED panels in combination with metal halide lamps

Yamashita Yukiko , Matsushita Yoshiki , Azuno Toru

… kW) and different numbers of MHs were carried out in August and September 2009 targeting two squid species: (1) Japanese common squid Todarodes pacificus in northern waters of the Sea of Japan (off Hokkaido) by 4 coastal squid jigging boats (19 gross tonnage) and (2) swordtip squid Photololigo edulis in western waters (off Iki) by 5 boats of the same class. …

Fisheries Research 113(1), 182-189, 2012-01

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3

Organizing Agreeing and Conflicting Opinions Based on Semantic Relation Recognition [in Japanese]

Junta Mizuno , Yotaro Watanabe , Eric Nichols , Koji Murakami , Kentaro Inui , Yuji Matsumoto

情報検索技術の発展により,あるトピックに関連する多様な情報を容易に入手できるようになった.しかしながら,これらの文書に記述されている情報には,不正確な記述,偏りのある意見などが多数混在している.そのため,個々の情報や意見の信憑性を判断するためには,多様な情報源からの意見との整合性を調べる必要がある.しかし,限られた時間で数多くの情報源を調べることは難しいため,ユーザが持っている先入観が正常な判断を …

Transactions of Information Processing Society of Japan 52(12), 3408-3422, 2011-12-15

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4

Targeting the Extracellular Signal-Regulated Kinase Pathway in Cancer Therapy

Kohno Michiaki , Tanimura Susumu , Ozaki Kei-ichi

The extracellular signal-regulated kinase (ERK) pathway is a major determinant in the control of diverse cellular processes such as proliferation, survival, and motility. This pathway is often upregul …

Biological and Pharmaceutical Bulletin 34(12), 1781-1784, 2011-12

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5

Targeting Angiogenesis in Cancer Therapy

Ichihara Eiki , Kiura Katsuyuki , Tanimoto Mitsune

Angiogenesis is an essential process in tumor growth. The concept of angiogenesis, when proposed by Folksman in 1971, had a great impact on cancer research and therapy, as the survival and proliferati …

Acta Medica Okayama 65(6), 353-362, 2011-12

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6

Optimal timing of insecticide fogging to minimize dengue cases: modeling dengue transmission among various seasonalities and transmission intensities.

Oki Mika , Sunahara Toshihiko , Hashizume Masahiro , Yamamoto Taro

… While insecticide fogging targeting the vector mosquito Aedes aegypti is a major control measure against dengue epidemics, the impact of this method remains controversial. …

PLoS Neglected Tropical Diseases 5(10), e1367, 2011-10

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7

The Effects of Internet Use on Internet Dependency, Psychological Health, and Interpersonal Relationships

KUMAZAKI(YAMAOKA) Ayuchi , MATSUO Yumi , SAKAMOTO Akira , AKIYAMA Kumiko , ADACHI Nireka , NAITO Mayumi , KURIE Ide , SAKAMOTO Katsura , TAKAHIRA Mieko , YONEZAWA Nobuyoshi

… A two-wave panel study between 1999 and 2000, targeting 314 students of engineering university (278 men, 36 women), showed that Internet use for all applications increased Internet dependency, In addition, a number of results showed that Internet dependency increased use, indicating that a bidirectional effect existed between Internet use and Internet dependency, and that they intensified each other. …

Journal of socio-informatics 4(1), 17-27, 2011-09-30

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8

Engagement of Overexpressed Her2 with GEP100 Induces Autonomous Invasive Activities and Provides a Biomarker for Metastases of Lung Adenocarcinoma

Menju Toshi , Hashimoto Shigeru , Hashimoto Ari , Otsuka Yutaro , Handa Haruka , Ogawa Eiji , Toda Yoshinobu , Wada Hiromi , Date Hiroshi , Sabe Hisataka

… Since the GEP100 PH domain interacts with both Her2 and EGFR, targeting this domain may provide novel cancer therapeutics. …

PLoS One 6(9), e25301, 2011-09-22

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9

Development of Effective Cancer Vaccine Using Targeting System of Antigen Protein to APCs.

Kurosaki Tomoaki , Kitahara Takashi , Nakamura Tadahiro , Nishida Koyo , Fumoto Shintaro , Kodama Yukinobu , Nakagawa Hiroo , Higuchi Norihide , Sasaki Hitoshi

… PURPOSE: To develop a novel cancer vaccine using the targeting system of antigen protein to antigen-presenting cells (APCs) for efficient and safe cancer therapy. …

Pharmaceutical Research -(-), -, 2011-09-02

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10

A-3-4 Minimization of Error Programs for Random Testing of C Compilers Targeting Arithmetic Expressions [in Japanese]

Nagai Eriko , Ishiura Nagisa

Proceedings of the Society Conference of IEICE 2011年_基礎・境界, 78, 2011-08-30

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11

Oxidative Stress and Mitochondrial Dysfunction in Neurovascular Injury after Stroke(<SPECIAL ISSUE>Neuroscience for the Development of Neurosurgery in the Near Futre)

Yoshioka Hideyuki , Sakata Hiroyuki , Okami Nobuya , Kinouchi Hiroyuki , Chan Pak H.

… Our neurovascular protective strategies targeting these two enzymes may expand the therapeutic window of the currently approved therapies. …

Japanese journal of neurosurgery 20(8), 559-565, 2011-08-20

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12

MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1

Dong Peixin , Kaneuchi Masanori , Watari Hidemichi , Hamada Junichi , Sudo Satoko , Ju Jingfang , Sakuragi Noriaki

Background: Epithelial-mesenchymal transition (EMT) is the key process driving cancer metastasis. Oncogene/self renewal factor BMI-1 has been shown to induce EMT in cancer cells. Recent studies have i …

Molecular Cancer 10, 99, 2011-08-18

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13

Nuclear translocation of glutathione S-transferase π is mediated by a non-classical localization signal.

Kawakatsu Miho , Goto Shinji , Yoshida Takako , Urata Yoshishige , Li Tao-Sheng

… Although the mitochondrial targeting signal of GSTπ was previously identified in the amino-terminal region, the mechanism of nuclear translocation remains completely unknown. …

Biochemical and Biophysical Research Communications 411(4), 745-750, 2011-08-12

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14

State of the Art for Measurement of Hydraulic Conductivity of Barrier Materials(<Theme>Continuity and Change in Geoenvironmental Engineering) [in Japanese]

Sato Kenichi , Inui Toru , Ozawa Kazuki , Fujimura Kenji , Ishimori Hiroyuki , Mukunoki Toshifumi

… In this report, the results of questionnaire targeting workers and researchers who perform the permeability test intended for the low-permeable materials are introduced, and the current state and issue are summarized. …

地盤工学会誌 59(8), 24-27, 2011-08-01

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15

Therapeutic Approaches to Vascular Protection in Ischemic Stroke

Yamashita Toru , Abe Koji

… Therapeutic targeting of free radicals and MMP-9/t-PA related signaling pathways might be promising approaches to minimizing catastrophic HT in acute stroke patients. …

Acta Medica Okayama 65(4), 219-223, 2011-08

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16

医療的ケアが必要な特別支援学校通学児の学校生活の適応に向けた母親への看護援助モデル作成 : 母親と教員の体験の聞き取りから [in Japanese]

小室佳文 , コムロカフミ , Komuro Kafumi

… The results suggested that nursing care targeting mothers promotes children's adjustment. …

千葉看護学会会誌 17(1), 9-16, 2011-08

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17

Roles of Pim-3, a novel survival kinase, in tumorigenesis

Mukaida Naofumi , Wang Ying-Ying , Li Ying-Yi

… Thus, Pim-3 kinase may be a candidate molecule for the development of molecular targeting drugs against cancer. …

Cancer Science 102(8), 1437-1442, 2011-08

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18

Roles of Pim-3, a novel survival kinase, in tumorigenesis

Mukaida Naofumi , Wang Ying-Ying , Li Ying-Yi

… Thus, Pim-3 kinase may be a candidate molecule for the development of molecular targeting drugs against cancer. …

Cancer Science 102(8), 1437-1442, 2011-08

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19

Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal

Sakurai Takeshi , Mieda Michihiro

… Recent findings have brought about the possibility of novel therapies targeting the orexin system for sleep disorders, including insomnia and narcolepsy-cataplexy, as well as other pathological conditions such as obesity and drug addiction . …

Trends in Pharmacological Sciences 32(8), 451-462, 2011-08

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20

The Brazilian Diaspora and the Media : With a Focus on the Transnational Strategies of Television and its Audiences(Multicultural Society and Media Communication) [in Japanese]

ISHI Angelo

… First, the strategies of Globo International, the biggest TV network in Brazil, which launched an international broadcasting service targeting Brazilian audiences abroad, are analyzed not only in terms of its programs, but also in terms of an event named "Brazilian Day," which Globo co-hosts in many countries. …

Journal of mass communication studies (79), 63-84, 2011-07-31

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Related Authors

Related Journals

Acta Medica Okayama
Cancer Science
Biochemical and Biophysical Research Communications
Biological and Pharmaceutical Bulletin
Fisheries Research
Gene
Japanese journal of neurosurgery
Journal of mass communication studies
Journal of socio-informatics
Molecular Cancer
PLoS Neglected Tropical Diseases
PLoS One
Pharmaceutical Research
Proceedings of the Society Conference of IEICE
Transactions of Information Processing Society of Japan
Trends in Pharmacological Sciences
千葉看護学会会誌
地盤工学会誌

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