Visualization of Functional Sites on Protein Structures by Virtual Reality Modeling Language

• Nakama Takao

  Advanced Technology Institute Inc.

• An Jianghong

  Tsukuba Life Science Center, The Institute of Physical & Chemical Research (RIKEN),

• C.H. Scott Adrian

  Aereal Inc.

• Kubota Yasushi

  Advanced Technology Institute Inc.

• Sarai Akinori

  Tsukuba Life Science Center, The Institute of Physical & Chemical Research (RIKEN),

抄録

We have integrated structural and functional information from proteins into a relational database, and built an interface to display the functional sites automatically mapped on the structure using Virtual Reality Modeling Language. The database contains link information between all the motifs in the PROSITE database and the peptide chains of protein structures in the Protein Data Bank. The functional sites are highlighted by different colors and hyperlinked to the corresponding document information containing descriptions of the motif and associated bibliographical data. Thus, the document information corresponding to the functional sites can be viewed by clicking the objects in the VRML display. This tool, which is accessible through the Internet (http://www.rtc.riken.go.jp/3DinSight.html), will help researchers gain insight into the relationship between structure and function in proteins.

収録刊行物

• bioimages

  bioimages 5 (2), 59-64, 1997

  日本バイオイメージング学会

キーワード

• protein structure
• functional sites
• motifs
• virtual reality

詳細情報

• CRID: 1390849376467539328
• NII論文ID: 10002038153
• NII書誌ID: AA11084187
• DOI: 10.11169/bioimages.5.59
• ISSN: 09192719
• 本文言語コード: en
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可