A Symbolic Representation for RNA Secondary Structures

  • Nakaya Akihiro
    Department of Genome Knowledge Discovery System, Institute of Medical Science, University of Tokyo
  • Yamamoto Kenji
    Laboratory of Clinical Microbiology and Immunology, Bun'in Hospital, Medical School, University of Tokyo

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Abstract

A nucleotide consists of phosphate, ribose, and one of the four bases adenine (A), guanine (G), cytosine (C), and uracil (U). The ribonucleic acid (RNA) molecule is a bio-polymer of those nucleotides. In this molecule, hydrogen bonds are formed between the bases (G ... C, A ... U, and G ... U) to make stable structures. If two adjacent nucleotides form hydrogen bonds with two other adjacent nucleotides, a stacking energy is generated to stabilize this structure. The structure determined by the stacking regions is called a secondary structure, and is known to contain many pieces of biological information. For a given RNA molecule, the position of the stacking regions can be determined by experiments or predicted by computer analyses. Several methods have been developed to visualize a secondary structure on a plane so that it can be understood easily. we·have developed a new method for the representation of RNA secondary structures by a sequential code, which can be transmitted by a network among computer systems easily.

Journal

  • bioimages

    bioimages 6 (2), 83-89, 1998

    Bioimaging Society

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Details

  • CRID
    1390845702295841408
  • NII Article ID
    10002038601
  • NII Book ID
    AA11084187
  • DOI
    10.11169/bioimages.6.83
  • ISSN
    09192719
  • Text Lang
    en
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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