A Symbolic Representation for RNA Secondary Structures
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- Nakaya Akihiro
- Department of Genome Knowledge Discovery System, Institute of Medical Science, University of Tokyo
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- Yamamoto Kenji
- Laboratory of Clinical Microbiology and Immunology, Bun'in Hospital, Medical School, University of Tokyo
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Abstract
A nucleotide consists of phosphate, ribose, and one of the four bases adenine (A), guanine (G), cytosine (C), and uracil (U). The ribonucleic acid (RNA) molecule is a bio-polymer of those nucleotides. In this molecule, hydrogen bonds are formed between the bases (G ... C, A ... U, and G ... U) to make stable structures. If two adjacent nucleotides form hydrogen bonds with two other adjacent nucleotides, a stacking energy is generated to stabilize this structure. The structure determined by the stacking regions is called a secondary structure, and is known to contain many pieces of biological information. For a given RNA molecule, the position of the stacking regions can be determined by experiments or predicted by computer analyses. Several methods have been developed to visualize a secondary structure on a plane so that it can be understood easily. we·have developed a new method for the representation of RNA secondary structures by a sequential code, which can be transmitted by a network among computer systems easily.
Journal
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- bioimages
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bioimages 6 (2), 83-89, 1998
Bioimaging Society
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Details
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- CRID
- 1390845702295841408
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- NII Article ID
- 10002038601
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- NII Book ID
- AA11084187
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- ISSN
- 09192719
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- Text Lang
- en
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed