Escherichia coli damage by ceramic powder slurries.

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  • Sawai Jun
    Department of Applied Chemistry, Kanagawa Institute of Technology
  • Kojima Hiromitsu
    Department of Applied Chemistry, Kanagawa Institute of Technology
  • Igarashi Hideo
    Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health
  • Hashimoto Atsushi
    Department of Bioinfromation, Mie University
  • Shoji Shinobu
    Department of Chemical Engineering, Division of Applied Chemistry, Tokyo University of Agriculture & Technology
  • Takehara Akemi
    Department of Chemical Engineering, Division of Applied Chemistry, Tokyo University of Agriculture & Technology
  • Sawaki Takashi
    Department of Chemical Engineering, Division of Applied Chemistry, Tokyo University of Agriculture & Technology
  • Kokugan Takao
    Department of Chemical Engineering, Division of Applied Chemistry, Tokyo University of Agriculture & Technology
  • Shimizu Masaru
    Department of Chemical Engineering, Division of Applied Chemistry, Tokyo University of Agriculture & Technology

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  • Escherichia Coli Damage by Ceramic Powd

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Abstract

To elucidate the antibacterial mechanisms of the ceramics magnesium oxide (MgO), calcium oxide (CaO) and zinc oxide (ZnO), damage to bacteria caused by these powder slurries are studied on the basis of change insensitivities to antibiotics, of which the primary inhibitory actions are understood well. Four kinds of antibiotics, penicillin G, chloramphenicol, nalidixic acid and rifampicin, were used as the selective reagents. The MgO and CaO powder slurries increased the sensitivities of Escherichia coli to rifampicin and chloramphenicol. Though the MgO and CaO powder slurries have high pH values, changes in the sensitivities by the MgO and CaO powder slurries were obviously different from those via alkaline treatment. The ZnO powder slurry enhanced the sensitivity of the E. coli to chloramphenicol. This result suggests that the antibacterial actions of MgO and CaO powder slurries were different from those of ZnO powder slurry.

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