Effect of Axial Dispersion on the Evaluation of Enantiomeric Ratio by a Fixed-Bed Reactor
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An earlier investigation has presented a novel procedure in the chromatographic reactor, capable of efficiently determining the enantioselectivity of the enzyme for a biocatalyzed process. In this work, a mathematical model including the effect of axial dispersion is formulated to describe the transient behavior of the fixed-bed used to evaluate the enantiomeric ratio. A valuable relationship among the enantioselectivity, Pèclet number, and transient responses at the exit of reactor is also established through the theoretical analysis. In addition, a relation is proposed to evaluate the significance of axial dispersion in the fixed-bed, allowing us to apply this criterion to assess the necessity of further studying the Pèclet number.
- JOURNAL OF CHEMICAL ENGINEERING OF JAPAN
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN 31(6), pp.999-1002, 1998-12-01
The Society of Chemical Engineers, Japan