“Structure and Functions of Archaebacterial Lipid Membranes”

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  • 古細菌脂質膜モデルと機能
  • コ サイキン シシツ マク モデル ト キノウ

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Abstract

Archaebacterial lipids are featured by C20-, C25-and C40-polyisoprenoid chains connected to a glycerol moiety by an ether linkage. The polyisoprenoid lipids including model compounds gave rise to double layer, unilayer and Q phase-like membranes. The morphology depended strongly on the structure of the lipids. The liposomal membranes made of the polyisoprenoid lipids were very stable at high temperature without undergoing morphological perturbation. The membranes were highly resistant to permeation of protons and various organic compounds as well as inorganic salts. It was also found that the surface energy of the molecular assemblies were extraordinally low, some approaching to the value of fluorocabon materials. These properties and functions were explained by fluidity of each polyisoprenoid chain and rigidity of an polyisoprenoid chain-array in the membranes.

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