Polyunsaturated Fatty Acids Production by Microbial Cultivation.

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  • 微生物の作る高度不飽和脂肪酸
  • ビセイブツ ノ ツクル コウド フホウワ シボウサン

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Abstract

Recent studies on the polyunsaturated fatty acid (PUFA) production by microorganisms and unicellular algae are reviewed. Lately, microbial lipid production, especially production of PUFA, difficult to obtain from plant or animal oils, has attracted general interest. However, not many researches on lipid production by microorganisms have been carried out. Industrial production of γ-linolenic acid from the Mortierella was already begun in Japan, as the first industrial application of “Single Cell Oil”. Production of arachidonic acid and the other C20- PUFAs were reported using Mortierella alpina and its mutants. Microbial production of docosahexaenoic acid (DHA) has been found in, Labyrinthulea, unicellular algae, and bacteria of marine origin, their growth rate or productivity were generally low. We isolated a new strain of marine fungi, Schizochytrium sp. that contained high levels of DHA and n-6 docosapentaenoic acid. High DHA productivity was due to high growth rate, and high lipid content of the strain. This strain is a promising resource for microbial DHA production as well as study on PUFA syntheses.

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