Evaluation of Toxicity of Lauryliminodicarboxylate by Cytokine Assay.

• SHIMADA Masahiko

  Oleochemicals Research Lab. NOF Corporation

• TAKEUCHI Kyu

  Oleochemicals Research Lab. NOF Corporation

Bibliographic Information

Other Title

• サイトカインアッセイによるラウリルイミノジカルボン酸塩の毒性に関する評価
• サイトカインアッセイ ニヨル ラウリルイミノジカルボンサンエン ノ ドクセイ

Abstract

Cytokine (interleukin ; IL) release related dermal acute inflammation was measured for normal human epidermal keratinocyte treated with lauryliminodiacetate (LIDA) and analogous surfactants. The relation of IL with surfactants was examined.<BR>Cytotoxicity introduced by LIDA appears involved in the release of IL-1α and IL-8, while no remarkable release of IL-1 α and IL-6 could be detected for lauryliminodipropionate (LIDP) at essentially the same concentration. For laurylaminoacetate (LAA) and laurylaminopropionate (LAP), greater IL-1 a and IL-6 release than LIDP was noted, indicating higher cytotoxicity. With sodium lauryl sulfate (SLS), IL-1α, IL-6 and IL-8 release was largest.

Journal

• Journal of Japan Oil Chemists' Society

  Journal of Japan Oil Chemists' Society 46 (11), 1403-1406, 1997

  Japan Oil Chemists' Society

Keywords

• cytokine
• interleukin
• normal human epidermal keratinocyte
• lauryl-imino-diacetate
• cytotoxicity

Details

• CRID: 1390282679068581248
• NII Article ID: 10002274620
• NII Book ID: AN10512582
• DOI: 10.5650/jos1996.46.1403
• ISSN: 18841996
• ISSN: 13418327
• NDL BIB ID: 4344232
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4344232
• Web Site: https://www.jstage.jst.go.jp/article/jos1996/46/11/46_11_1403/_pdf
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed