四本の長いアルキル鎖を有するビス第四アンモニウム塩類の合成と性質

• 竹澤 恒雄

  工学院大学工学部応用化学科

• 川辺 貴石

  工学院大学工学部応用化学科

• 梶山 哲人

  工学院大学工学部応用化学科

• 大勝 靖一

  工学院大学工学部応用化学科

書誌事項

タイトル別名

• Syntheses and Properties of Bis-Quaternary Ammonium Salts with Four Long-Alkyl Chains
• Syntheses and Properties of Bis-Quatern

抄録

Amphiphiles possessing two equivalent quaternary ammonium groups with one methyl, two dodecyls and a connecting alkanediyl chain of 2 to 20 carbons (m), alkanediyl-α, ω-bis (didodecyl-methylammonium bromide) [C_m-Bis (N-2 C₁₂)], were synthesized. <BR>Determination was made of the phase transition temperature (Tc) of C_m-Bis (N-2 C₁₂) and rate of probe leakage from the vesicles. In C_m-Bis (N-2 C₁₂) /water, Tc decreased with increase in m from 2 to 12 and then increased. The probe leakage (%), however, changed in reverse inclination with respect to m [24<6<8, 10<12, 14>16>20]. The membrane fluidity of vesicles is thus shown closely related to vesicle stability. <BR>The hydrolysis of an amino acid ester was carried out using vesicles of C_m-Bis (N-2 C₁₂) as a hydrolase model. Some tetra-alkylammonium salts showed hydrolyzing activity toward amino acid esters and the activity of C₁₂-Bis (N-2 C₁₂) was greater than that of glycolipid, which was proposed as hydrolase model by the authors.

収録刊行物

• 日本油化学会誌

  日本油化学会誌 47 (2), 149-157,208, 1998

  公益社団法人 日本油化学会

キーワード

• bis-quaternary ammonium salt
• synthesis
• vesicle
• phase transition temperature
• hydrolase model

詳細情報

• CRID: 1390001204091502848
• NII論文ID: 130001015555
• NII論文ID: 10002275140
• NII書誌ID: AN10512582
• DOI: 10.5650/jos1996.47.149
• ISSN: 18841996
• ISSN: 13418327
• NDL書誌ID: 4403026
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4403026
• Web Site: https://www.jstage.jst.go.jp/article/jos1996/47/2/47_2_149/_pdf
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