Transduction of Analytical Signals by Supramolecular Assemblies of Amphiphiles Containing Heterogeneously Distributed Fluorophores

この論文にアクセスする

この論文をさがす

著者

抄録

We report on the development and characterization of supramolecular assemblies of amphiphiles which are able to transduce changes of pH into optical signals. A series of assemblies have been investigated, including vesicular bilayer lipid membranes, monolayer films of fatty acids or phospholipids at the air-water interface, and covalently immobilized alkylsilane monolayers. In all cases, these membrane assemblies were formed from mixtures of species having zwitterionic and ionizable headgroups. In addition, a small amount of the fluorescently labeled phospholipid nitrobenzoxadiazole phosphatidylethanolamine (1 - 3%) was incorporated into the membranes. This resulted in systems which were able to transduce alterations of pH into changes in fluorescence intensity. Investigations into the physical mechanism responsible for alterations of fluorescence intensity from such membranes suggested that the nitro-benzoxadiazole phosphatidylethanolamine (NBD-PE) signal was based on changes of self-quenching of the probe which occurred when the physical and electrostatic characteristics of the membranes were altered. Useful signals were obtained only when microscopic phase separation existed within the membranes, indicating that careful design of the membrane was required to optimize the signal generated.

収録刊行物

  • Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 14(1), 141-150, 1998-02-10

    社団法人 日本分析化学会

参考文献:  31件中 1-31件 を表示

  • <no title>

    KRULL U. J.

    Analyst[London] 114, 33, 1989

    被引用文献2件

  • <no title>

    KRULL U. J.

    Int. J. Optoelectron. 4, 133, 1989

    被引用文献1件

  • <no title>

    KRULL U. J.

    Talanta 37, 561, 1990

    被引用文献1件

  • <no title>

    BRENNAN J. D.

    Chemically Modified Surfaces(Proceedings of the 4th Symposium on Chemically Modified Surfaces), 275-305, 1983

    被引用文献1件

  • <no title>

    SINGER S. J.

    Science[Washington, D. C. ] 175, 720, 1972

    被引用文献1件

  • <no title>

    WANG H.

    Appl. Biochem. Biotechnol. 53, 163, 1995

    被引用文献1件

  • <no title>

    KRULL U. J.

    Analyst[London] 115, 147, 1990

    被引用文献1件

  • <no title>

    LAKOWICZ J. R.

    Principles of Fluorescence Spectroscopy, 1983

    被引用文献15件

  • <no title>

    GAINES G.

    "Insoluble Monolayers at Liquid-Gas Interfaces" Interscience, 1966

    被引用文献1件

  • <no title>

    HECKL W. M.

    Bunsenyes. Phys. Chem. 90, 1159, 1986

    被引用文献1件

  • <no title>

    HECKL W. M.

    Biochim. Biophys. Acta 903, 166, 1987

    被引用文献1件

  • <no title>

    HECKL W. M.

    Langmuir 4, 1353, 1988

    被引用文献1件

  • <no title>

    HECKL W. M.

    Langmuir 5, 390, 1989

    被引用文献1件

  • <no title>

    ROBERTS G. G.

    Langmuir-Blodgett Films, 1990

    被引用文献7件

  • <no title>

    NETZER L.

    J. Am. Chem. Soc. 105, 674, 1983

    被引用文献6件

  • <no title>

    GUN J.

    J. Colloid Interface Sci. 112, 457, 1986

    被引用文献2件

  • <no title>

    BRENNAN J. D.

    Sensors Actuators B : Chemical 11, 109, 1993

    被引用文献1件

  • <no title>

    SHRIVE J. D. A.

    Appl. Spectrosc. 49, 304, 1995

    被引用文献1件

  • <no title>

    SHRIVE J. D. A.

    Langmuir 12, 4921, 1996

    被引用文献1件

  • <no title>

    BROWN R. S.

    Microchem. J. 50, 337, 1994

    被引用文献1件

  • <no title>

    BRENNAN J. D.

    Anal. Chim. Acta 255, 73, 1991

    被引用文献1件

  • <no title>

    MARSH D.

    CRC Handbook of Liqid Bilayers, 1990

    被引用文献1件

  • <no title>

    EIBL H.

    Biochim. Biophys. Acta 553, 476, 1979

    被引用文献1件

  • <no title>

    DUCHARME D.

    J. Phys. Chem. 94, 1925, 1990

    被引用文献1件

  • <no title>

    CEVC G.

    Phospholipid Bilayers : Physical Principles and Models, 1987

    被引用文献2件

  • <no title>

    BOGGS J. M.

    Acta. Rev. Biomemb. 906, 353, 1987

    被引用文献1件

  • <no title>

    JANATA J.

    Anal. Chem. 66, 207R, 1994

    被引用文献12件

  • <no title>

    BRENNAN J. D.

    Anal. Chim. Acta 237, 253, 1990

    DOI 被引用文献1件

  • <no title>

    von TSCHARNER V.

    Biophys. J. 36, 409, 1981

    被引用文献5件

  • <no title>

    BRENNAN J. D.

    Thin Solid Films 203, 73, 1991

    DOI 被引用文献1件

  • <no title>

    BROWN R. S.

    J. Chem. Phys. 100, 6019, 1994

    DOI 被引用文献2件

各種コード

  • NII論文ID(NAID)
    10002414436
  • NII書誌ID(NCID)
    AA10500785
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    09106340
  • NDL 記事登録ID
    4406436
  • NDL 雑誌分類
    ZP4(科学技術--化学・化学工業--分析化学)
  • NDL 請求記号
    Z54-F482
  • データ提供元
    CJP書誌  NDL  J-STAGE 
ページトップへ