Synthesis and Evaluation of a Bis(crown ether) Ionophore with a Conformationally Constrained Bridge in Ion-Selective Electrodes.

• XIA Zhiren

  Department of Chemistry, University of Kentucky

• BADR Ibrahim H. A.

  Department of Chemistry, University of Kentucky

• PLUMMER Shawn L.

  Department of Chemistry, University of Kentucky

• CULLEN Lawrence

  Department of Chemistry, University of Kentucky

• BACHAS Leonidas G.

  Department of Chemistry, University of Kentucky

Bibliographic Information

Other Title

• Synthesis and Evaluation of a Bis crown

Abstract

A new bis(crown ether) ionophore containing two benzo-15-crown-5 moieties connected with each other via a conformationally constrained bridge attached to a C₁₈-lipophilic side chain was designed and synthesized. The bridge consisted of an isophthalic acid derivative, which was selected in order to enhance potassium over sodium binding. Liquid-polymeric membrane ion-selective electrodes (ISEs) based on this ionophore were prepared using different plasticizers and mole ratios of lipophilic ionic additives. Membrane electrodes with optimum composition (using o-nitrophenyloctyl ether or bis(1-butylpentyl)adipate as plasticizer and 60 mol% lipophilic borate additive) show Nernstian responses toward potassium (57 and 58 mV/decade, respectively) over a wide concentration range with a micromolar detection limit. These ISEs exhibit enhanced potassium over sodium selectivity (K^pot_K+,Na+=6×10^-4). In addition, the electrodes show selectivities for potassium over Cs⁺ and NH₄⁺ that are better than those of valinomycin-based ISEs.

Journal

• Analytical Sciences

  Analytical Sciences 14 (1), 169-173, 1998

  The Japan Society for Analytical Chemistry

Keywords

• Analytical Chemistry

Details

• CRID: 1390001204253464832
• NII Article ID: 10002414548
• NII Book ID: AA10500785
• DOI: 10.2116/analsci.14.169
• COI: 1:CAS:528:DyaK1cXhtV2qtbk%3D
• ISSN: 13482246
• ISSN: 09106340
• NDL BIB ID: 4406440
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4406440
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.14.169.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.14.169/fulltext.html
• Web Site: http://www.jstage.jst.go.jp/article/analsci/14/1/14_1_169/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed