Analysis of Charged Cyclodextrin Derivatives by On-Line Capillary Electrophoresis-Ionspray-Mass Spectrometry.

• TANAKA Yoshihide

  Department of Analytical Chemistry, Nippon Boehringer Ingelheim Co. Ltd.

• KISHIMOTO Yasuhiro

  Department of Analytical Chemistry, Nippon Boehringer Ingelheim Co. Ltd.

• TERABE Shigeru

  Faculty of Science, Himeji Institute of Technology

書誌事項

タイトル別名

• Analysis of Charged Cyclodextrin Deriva

抄録

On-line capillary electrophoresis-ionspray-mass spectrometry (CE-ISP-MS) was applied to a composition analysis of charged cyclodextrin (CD) derivatives. Quaternary ammonium β-CD (QA-β-CD) and carboxymethylated γ-CD (CM-γ-CD), which were used as chiral selectors for enantiomer separations by CE, were analyzed. As for QA-β-CD, eight components having different degrees of the quaternary ammonium substitution could be identified based on their mass spectra. The components were detected as either molecular ions or fragment ions. On the other hand, six components of CM-γ-CD were detected as bivalent molecular ions. Such composition analyses were difficult using CE with only the UV detector. CE-MS was found to be a promising technique for a composition analysis of mixed compounds.

収録刊行物

• Analytical Sciences

  Analytical Sciences 14 (2), 383-388, 1998

  社団法人 日本分析化学会

キーワード

• Analytical Chemistry

詳細情報

• CRID: 1390001204254616320
• NII論文ID: 130004439820
• NII論文ID: 10002415334
• NII書誌ID: AA10500785
• DOI: 10.2116/analsci.14.383
• COI: 1:CAS:528:DyaK1cXislKltLo%3D
• ISSN: 13482246
• ISSN: 09106340
• NDL書誌ID: 4450426
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4450426
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.14.383.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.14.383/fulltext.html
• Web Site: http://www.jstage.jst.go.jp/article/analsci/14/2/14_2_383/_pdf
• 本文言語コード: en
• データソース種別:
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