Determination of Benzydamine Hydrochloride in Serum and Urine by Using a Benzydamine Ion-Selective Piezoelectric Sensor

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An ion-selective piezoelectric sensor (ISP) was developed for the rapid determination of benzydamine hydrochloride in serum and urine. The ISP device was fabricated by coating a PVC membrane containing benzydamine phosphotungstate on one electrode of a thickness-shear mode piezoelectric quartz crystal. The selective adsorption of benzydamine ion across the membrane caused a decrease in the oscillating frequency; also the logarithm of the frequency shift has a linear relation to the logarithm of the concentration of benzydamine over the ranges 2×10-7 - 8×10-3 M with a detection limit of 2.0×10-7 M at pH 7.0. Influencing factors were investigated and optimized. The results for real samples obtained by the proposed method were in agreement with those by the conventional non-aqueous titrimetric method.

収録刊行物

  • Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 14(5), 955-960, 1998-10-10

    社団法人 日本分析化学会

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各種コード

  • NII論文ID(NAID)
    10002417355
  • NII書誌ID(NCID)
    AA10500785
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    09106340
  • NDL 記事登録ID
    4576994
  • NDL 雑誌分類
    ZP4(科学技術--化学・化学工業--分析化学)
  • NDL 請求記号
    Z54-F482
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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