Simultaneous Determination of Four Components in Composite Vitamin B Tablets Using a Square-Root Kalman Filter
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A square-root Kalman filter combined with spectrometry has been applied to determining the concentrations of vitamin B1, vitamin B2, vitamin B6 and nicotinamide in synthetic mixtures and in a commercial composite vitamin B tablet. A simultaneous assay of the components in synthetic mixtures containing the above mentioned four B-complex vitamins was successfully achieved with satisfactory recoveries of 97.0 - 103.3%. The components in a commercial composite vitamin B tablet were determined simultaneously, and the obtained results are in good agreement with the labeled contents of the tablet.
- Analytical Sciences
Analytical Sciences 14(5), 965-969, 1998-10-10
The Japan Society for Analytical Chemistry