転写因子におけるDNA-蛋白質相互作用 DNA-protein Interactions by Transpcription Factors
The diversity of transcription factor-DNA complexes reviewed in this paper marks the extent of discovery since the first transcription factor-DNA co-crystal structures appeared less than ten years ago. The DNA-binding domains of transcription factors were classified into families, many of which have been identified by comparative amino acid sequence analysis. The three-dimensional views of their respective families revealed new designs as well as unanticipated similarities to older ones. Several hoped-for simplicities in their DNA-recognition mechanism have proved illusory, but other unexpected regularities have emerged.
日本結晶学会誌 39(3), 227-238, 1997-06-28
The Crystallographic Society of Japan