光回復酵素の結晶構造と補欠分子認識機構 [in Japanese] Crystal Structure of Photolyase Photoreactivating Enzyme [in Japanese]
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The crystal structure of 8-HDF type photolyase from <I>Anacystis nidulans</I> showed the similarity of the backbone structure with MTHF type <I>E. coli</I> photolyase but completely different binding site of the light-harvesting cofactor. This is a first example that homologous primary and tertiary structures in closely related proteins recognize two different types of cofactors at different binding-sites. The structure and function of photolyase and its cofactor recoginition are reviewed and discussed.
X-RAYS 40(5), 322-328, 1998-10-28
The Crystallographic Society of Japan